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The map label for this gene is dinF [H]

Identifier: 78065928

GI number: 78065928

Start: 1416229

End: 1417593

Strand: Reverse

Name: dinF [H]

Synonym: Bcep18194_A4457

Alternate gene names: 78065928

Gene position: 1417593-1416229 (Counterclockwise)

Preceding gene: 78065929

Following gene: 78065926

Centisome position: 38.37

GC content: 70.26

Gene sequence:

>1365_bases
ATGTCCGAATCCGCGTTACCGCACGGGGCCGGCTCGGCCGCCGTCACGCATCGGCGTGTCCTCGCGCTCGCGTTCCCGAT
CGTCCTCGCAAACCTGACCCAGCCGATCCTCGGTGCCGTCGACACGGCCGTCGCCGGTCACCTCGACGGCGCGCAGTACC
TCGGTGGCGTCGCGCTCGGCGGGCTGTTCTTCAATTTCGTGTTCTGGGGGTTCGGTTTCCTGCGGATGGGGACGACCGGC
CTCGTCGCGCAAGCGCACGGTGCCGGCGACGCTGCCGGAATCCGCCTGAACCTGCTGCGCGCGTTGATCGTCGCGTTCGC
ACTCGGCGCCGTGGTGCTGGCGCTGCAGGTGCCGCTGCTGTCCTTTGCGCTGTCCGCGCTCGGCGGCAGCGATGCCGTCC
GCACCACGGCGCTTGCCTACAGTCACGCGCGGATCTGGAGCGCACCGTTCGCGCTCGCGAACTACGTCGTGCTCGGCTAC
CTGCTCGGCATGCAGCGCGTGCGGCTCGCACTCGTCGCGCAGGTGTTCATCAATGCGGTGAACATCGGCGCCGTGCTGCT
CTACGTGTATGGCTTCGGCTGGGGCATTGCCGGCATCGGCGCCGCGACGGCCACCGCCGACGCATGCGGTTTCGCGCTCG
GCGCGTGGATGCTGTGGCGACTGCGGCCGCGCGGCCTTGCGCCGATCGCGGTACGCGCGCTCGCCGATCGCGTCGCGCTC
AAGCGGCTGATCGTACTCAATCGCGACATCTTCCTGCGCACGCTGTGCCTGCTCGGCGCATTCGGCTGGTTCGCGCACCT
TGGTGCGAAACAGGGCGATGCGACGCTCGCCGCAAACGCGCTGCTGCTGAATTTCCAGACGTTCATGGCGTACGGTCTCG
ACGGCTTCGCGCATGCGGCCGAGGCGCTCGTCGGCGCGGCGGCCGGCGCGCGCGACCGCCGCGCGTTCCGGCAGGCCGTG
CGCGTCACGCTGTTCTGGTCGGCGCTCGGCGCGCTGCTGTTCGCGCTCGTGTACTGGGCCGCCGGCGGCTGGATCATCGC
GCGCCTGACCGACCAGGCCGAGATCCGCGAAGTGGCGCTGCGTTACCTGCCGTGGGCCGCGATCTCGCCGATCGTGTCGG
TCTGGGGCTTCCTGCTCGACGGCGTCTTCATCGGCGCCACGCAGACGCAATCGCTGATGCGTGCGATGGTCGCATCGTTC
TCGATCTTCGTCGTGGCCACGCTCGCCGCCGTCGGCACATTCGGCAATCACGGCCTCTGGTTCGCGCTGCTGCTGTTCAT
GGCCGCACGCGGCGCGACGCTGGCGCGCTACCTGCCGGCGCTGTTGCGGCACATCGGCACCGACACGCCCGCGGCCCGCG
CCTGA

Upstream 100 bases:

>100_bases
GCCGAAACCGCCGCCGATTACGCGGCGCGCAACCCGGAGCTGTGGGCGGTCGTCGTATCGCCGTGGGTTTGCGTGCAAGA
ACGCGCCTGACGCGTCCGCC

Downstream 100 bases:

>100_bases
CGGCGGGCCGAACCGGCCGTTATTGCGTGGGTTTCGGCGGCGGCGCGTCGAGCATCGACGGCGGCGTCATGTCGGTCGGC
ACGCCGTGATAGTCGGCCGG

Product: multi anti extrusion protein MatE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSESALPHGAGSAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGAQYLGGVALGGLFFNFVFWGFGFLRMGTTG
LVAQAHGAGDAAGIRLNLLRALIVAFALGAVVLALQVPLLSFALSALGGSDAVRTTALAYSHARIWSAPFALANYVVLGY
LLGMQRVRLALVAQVFINAVNIGAVLLYVYGFGWGIAGIGAATATADACGFALGAWMLWRLRPRGLAPIAVRALADRVAL
KRLIVLNRDIFLRTLCLLGAFGWFAHLGAKQGDATLAANALLLNFQTFMAYGLDGFAHAAEALVGAAAGARDRRAFRQAV
RVTLFWSALGALLFALVYWAAGGWIIARLTDQAEIREVALRYLPWAAISPIVSVWGFLLDGVFIGATQTQSLMRAMVASF
SIFVVATLAAVGTFGNHGLWFALLLFMAARGATLARYLPALLRHIGTDTPAARA

Sequences:

>Translated_454_residues
MSESALPHGAGSAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGAQYLGGVALGGLFFNFVFWGFGFLRMGTTG
LVAQAHGAGDAAGIRLNLLRALIVAFALGAVVLALQVPLLSFALSALGGSDAVRTTALAYSHARIWSAPFALANYVVLGY
LLGMQRVRLALVAQVFINAVNIGAVLLYVYGFGWGIAGIGAATATADACGFALGAWMLWRLRPRGLAPIAVRALADRVAL
KRLIVLNRDIFLRTLCLLGAFGWFAHLGAKQGDATLAANALLLNFQTFMAYGLDGFAHAAEALVGAAAGARDRRAFRQAV
RVTLFWSALGALLFALVYWAAGGWIIARLTDQAEIREVALRYLPWAAISPIVSVWGFLLDGVFIGATQTQSLMRAMVASF
SIFVVATLAAVGTFGNHGLWFALLLFMAARGATLARYLPALLRHIGTDTPAARA
>Mature_453_residues
SESALPHGAGSAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGAQYLGGVALGGLFFNFVFWGFGFLRMGTTGL
VAQAHGAGDAAGIRLNLLRALIVAFALGAVVLALQVPLLSFALSALGGSDAVRTTALAYSHARIWSAPFALANYVVLGYL
LGMQRVRLALVAQVFINAVNIGAVLLYVYGFGWGIAGIGAATATADACGFALGAWMLWRLRPRGLAPIAVRALADRVALK
RLIVLNRDIFLRTLCLLGAFGWFAHLGAKQGDATLAANALLLNFQTFMAYGLDGFAHAAEALVGAAAGARDRRAFRQAVR
VTLFWSALGALLFALVYWAAGGWIIARLTDQAEIREVALRYLPWAAISPIVSVWGFLLDGVFIGATQTQSLMRAMVASFS
IFVVATLAAVGTFGNHGLWFALLLFMAARGATLARYLPALLRHIGTDTPAARA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=414, Percent_Identity=42.7536231884058, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47817; Mature: 47686

Theoretical pI: Translated: 11.18; Mature: 11.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SESALPHGAGSAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGAQYLGGVALG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH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HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]