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The map label for this gene is pccB [H]

Identifier: 78065885

GI number: 78065885

Start: 1372844

End: 1373848

Strand: Direct

Name: pccB [H]

Synonym: Bcep18194_A4414

Alternate gene names: 78065885

Gene position: 1372844-1373848 (Clockwise)

Preceding gene: 78065884

Following gene: 78065886

Centisome position: 37.16

GC content: 70.75

Gene sequence:

>1005_bases
ATGAACACCCCCCACGCTCACATCCATTCGCTGCCCCCCGAGGGGGCCGGTGCCTCCCCAGGGGCGGAGGCGCCGAACGA
CGTGATCCACGACGCACCGGCGTTCGTCGCGAACGCCGCGAGCTGGTACGAAGCGTCGGCGCGGCAGCGCATCGACGGGC
TGCTCGACGCCGGCAGTTTCAGTGAATTCCTCGGTCCGGCCGAGCGCGTGACGAGCCCGCACTTGCCGCTGTTCGACCTG
CCGCAGCAGTTCGACGACGGGATGGTGGTCGGCCACGGCCGGCTCGACGGCCAGCCGGTGTTCGTCGCCGCGCAGGAAGG
CCGCTTCATGGGCGGCGCGTTCGGCGAAGTGCACGGCGCGAAGCTCACCGGGCTGCTGCGTGCCGCGCGCGAAACCGGCA
AGCCGGTGCTGATCCTGTTCGATACGGGTGGCGTGCGGCTGCAGGAAGCGAACGCGGGCGAACTCGCGATCGCCGAGATC
ATGCGCGCGCTCGTCGAAGCGCGCACGGCCGGCGTGCCGGTGATCGGGCTGATCGGCGGGCGCGCGGGCTGCTATGGCGG
CGGCGGGTTGCTCGCCGCGTGCTGCTCGGCGCTCGCAGTATCGGAGCAGGGCCGCATCAGCGTGTCGGGCCCCGAAGTGA
TCGAGACCAATCGCGGCGTCGAGGAATTCGATGCGAAGGACCGCGCGCTGATCTGGCGCACGATGGGCGGCAAGCACCGG
CGGCTGATCGGCGGCGCGGATCGCTACGTGGCCGACACGCCCGATGCGTTCCGTGCGGTGGCGCTCGAGCTGATCGGCCG
CGCGCCGAAATTCGATGCGGCAATGCTGCGCGCGGAACAGGCGCGCCTCGAAGCGCGTGTCGAGCGATTCGGTGCATGCA
ACGATGCACTCGACGTGTGGCGTGCGCTGGGCGCATCGGCGCCGGAAGCGATTCCGGGGATGCCGGACGATGCCTTCGCC
GCGCTCGCGGACCAACTGCAGGAGAGCCCGCATGACGCTCGATGA

Upstream 100 bases:

>100_bases
CGGGCGGTTTGAAGCTGTCGATCAATGACGGCGGCGCGCGGCCCGACATGGTGTCGCTGCGGCTCGCACAGGCGGTGCGA
GCGATCGAGGGAGACGCGCA

Downstream 100 bases:

>100_bases
ATTACTGAATTCACTGTTCCCGCAAGGCCATTGGATCGCCCGTGACGGCGGCCTGCTGACCGGCCACGCGGAGCTGGCCG
GCACGCGCGTCGACGTGATC

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNTPHAHIHSLPPEGAGASPGAEAPNDVIHDAPAFVANAASWYEASARQRIDGLLDAGSFSEFLGPAERVTSPHLPLFDL
PQQFDDGMVVGHGRLDGQPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARETGKPVLILFDTGGVRLQEANAGELAIAEI
MRALVEARTAGVPVIGLIGGRAGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHR
RLIGGADRYVADTPDAFRAVALELIGRAPKFDAAMLRAEQARLEARVERFGACNDALDVWRALGASAPEAIPGMPDDAFA
ALADQLQESPHDAR

Sequences:

>Translated_334_residues
MNTPHAHIHSLPPEGAGASPGAEAPNDVIHDAPAFVANAASWYEASARQRIDGLLDAGSFSEFLGPAERVTSPHLPLFDL
PQQFDDGMVVGHGRLDGQPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARETGKPVLILFDTGGVRLQEANAGELAIAEI
MRALVEARTAGVPVIGLIGGRAGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHR
RLIGGADRYVADTPDAFRAVALELIGRAPKFDAAMLRAEQARLEARVERFGACNDALDVWRALGASAPEAIPGMPDDAFA
ALADQLQESPHDAR
>Mature_334_residues
MNTPHAHIHSLPPEGAGASPGAEAPNDVIHDAPAFVANAASWYEASARQRIDGLLDAGSFSEFLGPAERVTSPHLPLFDL
PQQFDDGMVVGHGRLDGQPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARETGKPVLILFDTGGVRLQEANAGELAIAEI
MRALVEARTAGVPVIGLIGGRAGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHR
RLIGGADRYVADTPDAFRAVALELIGRAPKFDAAMLRAEQARLEARVERFGACNDALDVWRALGASAPEAIPGMPDDAFA
ALADQLQESPHDAR

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=180, Percent_Identity=31.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788655, Length=185, Percent_Identity=32.4324324324324, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147362, Length=184, Percent_Identity=32.0652173913043, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147359, Length=184, Percent_Identity=32.0652173913043, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 35054; Mature: 35054

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPHAHIHSLPPEGAGASPGAEAPNDVIHDAPAFVANAASWYEASARQRIDGLLDAGSF
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SEFLGPAERVTSPHLPLFDLPQQFDDGMVVGHGRLDGQPVFVAAQEGRFMGGAFGEVHGA
HHHCCCHHHHCCCCCCHHCCCHHCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHCHH
KLTGLLRAARETGKPVLILFDTGGVRLQEANAGELAIAEIMRALVEARTAGVPVIGLIGG
HHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
RAGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHR
CCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCHHHHCCCCCEEEEECCCCCCE
RLIGGADRYVADTPDAFRAVALELIGRAPKFDAAMLRAEQARLEARVERFGACNDALDVW
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RALGASAPEAIPGMPDDAFAALADQLQESPHDAR
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNTPHAHIHSLPPEGAGASPGAEAPNDVIHDAPAFVANAASWYEASARQRIDGLLDAGSF
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SEFLGPAERVTSPHLPLFDLPQQFDDGMVVGHGRLDGQPVFVAAQEGRFMGGAFGEVHGA
HHHCCCHHHHCCCCCCHHCCCHHCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHCHH
KLTGLLRAARETGKPVLILFDTGGVRLQEANAGELAIAEIMRALVEARTAGVPVIGLIGG
HHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
RAGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHR
CCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCHHHHCCCCCEEEEECCCCCCE
RLIGGADRYVADTPDAFRAVALELIGRAPKFDAAMLRAEQARLEARVERFGACNDALDVW
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RALGASAPEAIPGMPDDAFAALADQLQESPHDAR
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]