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The map label for this gene is ykuU [H]

Identifier: 78065772

GI number: 78065772

Start: 1241589

End: 1242140

Strand: Direct

Name: ykuU [H]

Synonym: Bcep18194_A4300

Alternate gene names: 78065772

Gene position: 1241589-1242140 (Clockwise)

Preceding gene: 78065769

Following gene: 78065774

Centisome position: 33.61

GC content: 64.86

Gene sequence:

>552_bases
ATGAAGCGAAAACTGTTGCTGGGCGCCGCCGTGGCGGCGCTGGTGGCCGGCCATGCGCTGATGGCGCAGGCGGAATTGAA
GCCGGGTGCCGCGGCGCCCGATTTCACGACGCAGGCGTCGCTGGGCGGCAAGACTTACACGTACTCGCTCGCGGACGCGC
TGAAGCAGGGGCCGGTCGTGCTGTATTTCTACCCGGCCGCGTTCACGAAGGGCTGCACGATCGAGGCGCACGCGTTCGCG
GACGCGGTCGACCGTTACAAGGCTTACGGCGCGACGGTGATCGGCGTATCGGCTGACAAGATCGACACGCTGACGAAGTT
CTCGGTGAGCGAGTGCCGGAGCAAGTTCCCGGTCGCGGCCGATCCGGACGCGAAGATCATCCGGGAATACGACGCGAAGC
TGCCGGCGATCGACAAGGCGAACCGCGTGTCCTACGTGATTTCGCCGGAAGGGAAGATTCTCTACGAATACACGAGCATG
TCGCCCGACAAGCACGTCGAGAACACGCTCGCCGCCGTGAAGGCGTGGGCGGACGCGCATCCGAAGCAGTAA

Upstream 100 bases:

>100_bases
ATGGCATGGCCGCTGGACCGGATCGGTCACGCAGGTGTTCGACAGGCGAACGCCGGCGGGGCCTACATCGAGGCTGACTT
TATAAGAAATGAGGACGCAG

Downstream 100 bases:

>100_bases
GCGGATGCCCGTACGTCAAGGCGGCCCGTCGTGCGGGCCGCCGGTACGAAGCAGCGCGCCGCCCGCGCGGCGGCGCGCGT
GAGCCTGCTAGGCGCGCAAT

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: Acceptor; H2O; oxidized thioredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKRKLLLGAAVAALVAGHALMAQAELKPGAAAPDFTTQASLGGKTYTYSLADALKQGPVVLYFYPAAFTKGCTIEAHAFA
DAVDRYKAYGATVIGVSADKIDTLTKFSVSECRSKFPVAADPDAKIIREYDAKLPAIDKANRVSYVISPEGKILYEYTSM
SPDKHVENTLAAVKAWADAHPKQ

Sequences:

>Translated_183_residues
MKRKLLLGAAVAALVAGHALMAQAELKPGAAAPDFTTQASLGGKTYTYSLADALKQGPVVLYFYPAAFTKGCTIEAHAFA
DAVDRYKAYGATVIGVSADKIDTLTKFSVSECRSKFPVAADPDAKIIREYDAKLPAIDKANRVSYVISPEGKILYEYTSM
SPDKHVENTLAAVKAWADAHPKQ
>Mature_183_residues
MKRKLLLGAAVAALVAGHALMAQAELKPGAAAPDFTTQASLGGKTYTYSLADALKQGPVVLYFYPAAFTKGCTIEAHAFA
DAVDRYKAYGATVIGVSADKIDTLTKFSVSECRSKFPVAADPDAKIIREYDAKLPAIDKANRVSYVISPEGKILYEYTSM
SPDKHVENTLAAVKAWADAHPKQ

Specific function: Unknown

COG id: COG1225

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788825, Length=158, Percent_Identity=29.746835443038, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19573; Mature: 19573

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKLLLGAAVAALVAGHALMAQAELKPGAAAPDFTTQASLGGKTYTYSLADALKQGPVV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCEEEEHHHHHHHHCCEE
LYFYPAAFTKGCTIEAHAFADAVDRYKAYGATVIGVSADKIDTLTKFSVSECRSKFPVAA
EEEECCCCCCCCEEEHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
DPDAKIIREYDAKLPAIDKANRVSYVISPEGKILYEYTSMSPDKHVENTLAAVKAWADAH
CCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCC
PKQ
CCC
>Mature Secondary Structure
MKRKLLLGAAVAALVAGHALMAQAELKPGAAAPDFTTQASLGGKTYTYSLADALKQGPVV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCEEEEHHHHHHHHCCEE
LYFYPAAFTKGCTIEAHAFADAVDRYKAYGATVIGVSADKIDTLTKFSVSECRSKFPVAA
EEEECCCCCCCCEEEHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
DPDAKIIREYDAKLPAIDKANRVSYVISPEGKILYEYTSMSPDKHVENTLAAVKAWADAH
CCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCC
PKQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced acceptor; H2O2; reduced thioredoxin [C]

Specific reaction: reduced acceptor + H2O2 = Acceptor + H2O reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: Oxidoreductases; Acting on a peroxide as acceptor; Peroxidase [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]