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The map label for this gene is astE

Identifier: 78065768

GI number: 78065768

Start: 1235726

End: 1236781

Strand: Direct

Name: astE

Synonym: Bcep18194_A4296

Alternate gene names: 78065768

Gene position: 1235726-1236781 (Clockwise)

Preceding gene: 78065767

Following gene: 78065769

Centisome position: 33.45

GC content: 70.74

Gene sequence:

>1056_bases
ATGACTTCCAGCGTTGATTCGCGCATGGCCGACGCGCTGCTCGACGACTTCCTCGCGTTCACGCTGACCGGCAGCGCACC
GTCCGCCACGGACGGCGCCTGCGCCGCCGGCGCCGTGCGCTGGCAATGGCTCGGCGACGGGCTGCTCGCCCTCGAACCGG
CTGCGGCCGAGGCCGCCGATACGGCGCGCGCGAGCGTGCTGGTGTCGGCCGGCGTGCACGGTGACGAGACGGCGCCGATC
GAGCTGCTGTCGATGCTGGTGCGCGATCTTGCATCGGGGGCGCTGCCGCTCGCGTGCCGGCTGCTCGTCGTGCTCGGCAA
CGTGCCGGCGATGCGCGCCGGTGAACGCTATCTCGACGACGACCTGAACCGCCTGTTCAGCGGCCGTCACGCGCAGGTGC
CCGACAGTCGCGAAGCGCCGCGTGCCACGCAGCTCGAAGCCGCTGCCGCCGCGTTCTTCGCGGCCGCGCCGGCCGGCGCC
GCGCGCTGGCACATCGACATGCATACGGCGATCCGCGCATCGGTGTTCGAGCAGTTCGCCCTGCTGCCGCATACGGGCAT
GCCGCCGACGCGCACGATGTTCGAATGGCTCGGCGACGCGCAGATCGCGGCCGTGCTGCTGCATACCGCGAAGGGCAACA
CGTACTCGCATTTCACGGCCGAGCACTGCGGCGCGCTCGCGTGCACGCTGGAACTCGGCAAGGTGCGTCCGTTCGGCCAG
AACGACCTGACGCGCTTCGCGCCGGCCGACCGCGCGGTGCGCAAGCTCGTGTCGGGCGCGACTGGTGAGGCCGACGTCCC
GTTGCCGCGCGTCTTCACGGTGATCGACCAGATCACGAAGCAGAGCGACGCGCTCGAGTTGTTCGTCGCGGCCGACGTCG
CGAACTTCACCGCGTTCGCACGCGGCACGGTGCTCGCGCAGGACGGCGACTACCGCTACACGGTGACGCACGACGAGGAG
CGCATCGTGTTCCCGAATCCGTCGGTGAAGCCGGGTTTGCGCGCGGGTCTGCTCGTCATCGACACGACTCGCGAGACGGT
CGCGGCGCTCGTCTGA

Upstream 100 bases:

>100_bases
GATCGCCTCGCACCGGAAGACCTCGCCGATCCGGCGCTGCTCGAGGAATCGCGCACGGCGCTCGACGAGCTCACGCAGAT
CCTGCGCGTCGGTTCGCTGT

Downstream 100 bases:

>100_bases
CGGTGGCCGATTGCGCGTGGCCGCGGCGACCTGCGGCCCGCGCATCACCCGGCCACCATTCCGTTTTCGAGATTAAGCCC
GCACGCCGCGCAGATGGCCC

Product: succinylglutamate desuccinylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTSSVDSRMADALLDDFLAFTLTGSAPSATDGACAAGAVRWQWLGDGLLALEPAAAEAADTARASVLVSAGVHGDETAPI
ELLSMLVRDLASGALPLACRLLVVLGNVPAMRAGERYLDDDLNRLFSGRHAQVPDSREAPRATQLEAAAAAFFAAAPAGA
ARWHIDMHTAIRASVFEQFALLPHTGMPPTRTMFEWLGDAQIAAVLLHTAKGNTYSHFTAEHCGALACTLELGKVRPFGQ
NDLTRFAPADRAVRKLVSGATGEADVPLPRVFTVIDQITKQSDALELFVAADVANFTAFARGTVLAQDGDYRYTVTHDEE
RIVFPNPSVKPGLRAGLLVIDTTRETVAALV

Sequences:

>Translated_351_residues
MTSSVDSRMADALLDDFLAFTLTGSAPSATDGACAAGAVRWQWLGDGLLALEPAAAEAADTARASVLVSAGVHGDETAPI
ELLSMLVRDLASGALPLACRLLVVLGNVPAMRAGERYLDDDLNRLFSGRHAQVPDSREAPRATQLEAAAAAFFAAAPAGA
ARWHIDMHTAIRASVFEQFALLPHTGMPPTRTMFEWLGDAQIAAVLLHTAKGNTYSHFTAEHCGALACTLELGKVRPFGQ
NDLTRFAPADRAVRKLVSGATGEADVPLPRVFTVIDQITKQSDALELFVAADVANFTAFARGTVLAQDGDYRYTVTHDEE
RIVFPNPSVKPGLRAGLLVIDTTRETVAALV
>Mature_350_residues
TSSVDSRMADALLDDFLAFTLTGSAPSATDGACAAGAVRWQWLGDGLLALEPAAAEAADTARASVLVSAGVHGDETAPIE
LLSMLVRDLASGALPLACRLLVVLGNVPAMRAGERYLDDDLNRLFSGRHAQVPDSREAPRATQLEAAAAAFFAAAPAGAA
RWHIDMHTAIRASVFEQFALLPHTGMPPTRTMFEWLGDAQIAAVLLHTAKGNTYSHFTAEHCGALACTLELGKVRPFGQN
DLTRFAPADRAVRKLVSGATGEADVPLPRVFTVIDQITKQSDALELFVAADVANFTAFARGTVLAQDGDYRYTVTHDEER
IVFPNPSVKPGLRAGLLVIDTTRETVAALV

Specific function: Transforms N(2)-succinylglutamate into succinate and glutamate

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily

Homologues:

Organism=Escherichia coli, GI1788040, Length=327, Percent_Identity=46.177370030581, Blast_Score=298, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTE_BURS3 (Q39I23)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_368537.1
- HSSP:   Q9KSL4
- ProteinModelPortal:   Q39I23
- SMR:   Q39I23
- STRING:   Q39I23
- GeneID:   3749495
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A4296
- NMPDR:   fig|269483.3.peg.5516
- eggNOG:   COG2988
- HOGENOM:   HBG298271
- OMA:   RWRWLGH
- ProtClustDB:   PRK05324
- BioCyc:   BSP36773:BCEP18194_A4296-MONOMER
- HAMAP:   MF_00767
- InterPro:   IPR007036
- InterPro:   IPR016681
- PIRSF:   PIRSF017020
- TIGRFAMs:   TIGR03242

Pfam domain/function: PF04952 AstE_AspA

EC number: =3.5.1.96

Molecular weight: Translated: 37232; Mature: 37100

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: ACT_SITE 231-231

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSVDSRMADALLDDFLAFTLTGSAPSATDGACAAGAVRWQWLGDGLLALEPAAAEAAD
CCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCEEEEEECCCCEEECCCHHHHHH
TARASVLVSAGVHGDETAPIELLSMLVRDLASGALPLACRLLVVLGNVPAMRAGERYLDD
HHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCHHHHH
DLNRLFSGRHAQVPDSREAPRATQLEAAAAAFFAAAPAGAARWHIDMHTAIRASVFEQFA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHH
LLPHTGMPPTRTMFEWLGDAQIAAVLLHTAKGNTYSHFTAEHCGALACTLELGKVRPFGQ
HCCCCCCCCHHHHHHHHCCHHEEHHHHECCCCCCCCCCCHHHHCEEEEEEECCCCCCCCC
NDLTRFAPADRAVRKLVSGATGEADVPLPRVFTVIDQITKQSDALELFVAADVANFTAFA
CCCHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHH
RGTVLAQDGDYRYTVTHDEERIVFPNPSVKPGLRAGLLVIDTTRETVAALV
CCEEEEECCCEEEEEECCCCEEECCCCCCCCCCCCCEEEEECCHHHHHHCC
>Mature Secondary Structure 
TSSVDSRMADALLDDFLAFTLTGSAPSATDGACAAGAVRWQWLGDGLLALEPAAAEAAD
CCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCEEEEEECCCCEEECCCHHHHHH
TARASVLVSAGVHGDETAPIELLSMLVRDLASGALPLACRLLVVLGNVPAMRAGERYLDD
HHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCHHHHH
DLNRLFSGRHAQVPDSREAPRATQLEAAAAAFFAAAPAGAARWHIDMHTAIRASVFEQFA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHH
LLPHTGMPPTRTMFEWLGDAQIAAVLLHTAKGNTYSHFTAEHCGALACTLELGKVRPFGQ
HCCCCCCCCHHHHHHHHCCHHEEHHHHECCCCCCCCCCCHHHHCEEEEEEECCCCCCCCC
NDLTRFAPADRAVRKLVSGATGEADVPLPRVFTVIDQITKQSDALELFVAADVANFTAFA
CCCHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHH
RGTVLAQDGDYRYTVTHDEERIVFPNPSVKPGLRAGLLVIDTTRETVAALV
CCEEEEECCCEEEEEECCCCEEECCCCCCCCCCCCCEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA