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The map label for this gene is degP [H]

Identifier: 78065714

GI number: 78065714

Start: 1175777

End: 1177279

Strand: Direct

Name: degP [H]

Synonym: Bcep18194_A4242

Alternate gene names: 78065714

Gene position: 1175777-1177279 (Clockwise)

Preceding gene: 78065713

Following gene: 78065715

Centisome position: 31.83

GC content: 67.33

Gene sequence:

>1503_bases
ATGATGAAACTCACGCTGCGCAAATGGCTCGCGGCGGCGGCGCTGTCTGCCTGCCTGCCGCTCGTGCCGCATACCGCGTT
CGCGGTGACGGCTCCCGCTGCCAGCCTGCCCGACTTCGCCGACCTGGTCGAAAAGGTCGGGCCGGCCGTCGTGAACATCC
GGACCACCGCCAACGTGCCGACGAGCAGCGGCCCGCGCGGGATGCTCCCGCCGGGCTTCGACAACGGCGACATGTCGGAA
TTCTTCCGGCGCTTCTTCGGCATTCCGCTGCCGCAGGCGCCCGGTAACGGTAGCGGCAACGGCGGCAACAACCCGAAGAA
CGCGCCCGCGCCGGACAACCCGCCCGATACCGAACAGAATCGCGGCGTCGGCTCGGGCTTCATCGTGTCGGCCGACGGTT
ACGTGATGACCAATGCGCACGTCGTCGACGACGCGGACACCATCTACGTGACGCTGACCGACAAGCGCGAATTCAAGGCG
AAGCTGATCGGCGTCGACGATCGCACGGACGTCGCGGTCGTCAAGATCCAGGCGTCGAACCTGCCGGTCGTCGCGATCGG
CGATTCGAACAAGGTGCGCGTCGGCGAGTGGGTTGTCGCGATCGGTTCGCCGTTCGGCCTCGACAACACGGTGACGGCCG
GCATCGTCAGCTCGAAGAGCCGCAATACGGGCGACTACCTGCCGTTCATCCAGACCGACGTCGCCGTGAACCCCGGCAAC
TCGGGCGGCCCGCTGATCAACATGCAGGGCGAGGTGATCGGCATCAACTCGCAGATCTACAGCCGTACCGGCGGTTTCAT
GGGCATCTCGTTCGCGATTCCGATCGACGAGGCGATGCGCGTGGCCGACCAGCTGAAGGCGACGGGCAAGGTCACGCGCG
GCCGGATCGCGGTCGCGATCGGCGAGGTGACGAAGGACGTGGCCGATTCGATCGGGTTGCCGAAGGCCGAGGGTGCGCTC
GTCAGCAGCGTCGAGCCGGGCGGTCCGGCCGACAAGGCGGGCATCCAGCCGGGCGACATCATCCTGAAGTTCAATGGCCG
TTCGGTCGATACGGCGTCGGACCTGCCGCGCATGGTCGGCGACACGAAGCCCGGCGCGAAGGCGACGGTCAGCGTATGGC
GCAAGGGTCAGGCACGCGATCTGCCGATCACGATCGCGGAGACGCCGGCCGAAACGACGGCGAAGGCCGAGCAGCGCAAG
AATGCGCCGCAGAAGCCGCGCCAGACCAATTCGCTCGGCCTGACGGTCAGTGATCTGACGGCGGAGCAGATGAAGACGCT
GAAGCTGAAGAACGGCGTGCAGATCGACGGCGTAGACGGCCCGGCCGCCCGTGCGGGCCTGCAGCGCGGTGACATCGTGC
TGCGCGTCGGCGACACCGACATCACGAACGCGAAGCAGTTTGCCGACGTGACCGCGCAGCTCGATCCGCAGAAGGCGGTC
GCGGTGCTCGTGCGGCGTGGCGACAACACGCAGTTCGTGCCCGTGCGGCCGCGCCAGAAGTAA

Upstream 100 bases:

>100_bases
TACTGGATCACCGTGCTCGGCGAAGTGCCGCCGGCTACGTTGCAGCAGTTCGCGTCTGCCATAGAATACAAGGCTTCCAA
GTAACGCTACGGCTTCCGAC

Downstream 100 bases:

>100_bases
CGCGCCGATGTTCACGCTCTACGGCCGCGGCTGGTGCCACCTGTGCGACGACATGCGCGACGCACTGGCGCCGGTGGCGG
CCGAATTCGGTGTCGCGGTC

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MMKLTLRKWLAAAALSACLPLVPHTAFAVTAPAASLPDFADLVEKVGPAVVNIRTTANVPTSSGPRGMLPPGFDNGDMSE
FFRRFFGIPLPQAPGNGSGNGGNNPKNAPAPDNPPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKA
KLIGVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGN
SGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGAL
VSSVEPGGPADKAGIQPGDIILKFNGRSVDTASDLPRMVGDTKPGAKATVSVWRKGQARDLPITIAETPAETTAKAEQRK
NAPQKPRQTNSLGLTVSDLTAEQMKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITNAKQFADVTAQLDPQKAV
AVLVRRGDNTQFVPVRPRQK

Sequences:

>Translated_500_residues
MMKLTLRKWLAAAALSACLPLVPHTAFAVTAPAASLPDFADLVEKVGPAVVNIRTTANVPTSSGPRGMLPPGFDNGDMSE
FFRRFFGIPLPQAPGNGSGNGGNNPKNAPAPDNPPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKA
KLIGVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGN
SGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGAL
VSSVEPGGPADKAGIQPGDIILKFNGRSVDTASDLPRMVGDTKPGAKATVSVWRKGQARDLPITIAETPAETTAKAEQRK
NAPQKPRQTNSLGLTVSDLTAEQMKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITNAKQFADVTAQLDPQKAV
AVLVRRGDNTQFVPVRPRQK
>Mature_500_residues
MMKLTLRKWLAAAALSACLPLVPHTAFAVTAPAASLPDFADLVEKVGPAVVNIRTTANVPTSSGPRGMLPPGFDNGDMSE
FFRRFFGIPLPQAPGNGSGNGGNNPKNAPAPDNPPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKA
KLIGVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGN
SGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGAL
VSSVEPGGPADKAGIQPGDIILKFNGRSVDTASDLPRMVGDTKPGAKATVSVWRKGQARDLPITIAETPAETTAKAEQRK
NAPQKPRQTNSLGLTVSDLTAEQMKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITNAKQFADVTAQLDPQKAV
AVLVRRGDNTQFVPVRPRQK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=280, Percent_Identity=39.2857142857143, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI22129776, Length=262, Percent_Identity=38.5496183206107, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=36.4, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=39.8406374501992, Blast_Score=149, Evalue=5e-36,
Organism=Escherichia coli, GI1789629, Length=501, Percent_Identity=35.7285429141717, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1786356, Length=474, Percent_Identity=33.9662447257384, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI1789630, Length=285, Percent_Identity=38.2456140350877, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=38.9312977099237, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52409; Mature: 52409

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLTLRKWLAAAALSACLPLVPHTAFAVTAPAASLPDFADLVEKVGPAVVNIRTTANVP
CCEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEEEECCCC
TSSGPRGMLPPGFDNGDMSEFFRRFFGIPLPQAPGNGSGNGGNNPKNAPAPDNPPDTEQN
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASN
CCCCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECC
LPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGN
CCEEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCC
SGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAI
CCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEE
GEVTKDVADSIGLPKAEGALVSSVEPGGPADKAGIQPGDIILKFNGRSVDTASDLPRMVG
HHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHC
DTKPGAKATVSVWRKGQARDLPITIAETPAETTAKAEQRKNAPQKPRQTNSLGLTVSDLT
CCCCCCCEEHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHC
AEQMKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITNAKQFADVTAQLDPQKAV
HHHHHHHHHCCCCEEECCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHEE
AVLVRRGDNTQFVPVRPRQK
EEEEECCCCCEEEECCCCCC
>Mature Secondary Structure
MMKLTLRKWLAAAALSACLPLVPHTAFAVTAPAASLPDFADLVEKVGPAVVNIRTTANVP
CCEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEEEECCCC
TSSGPRGMLPPGFDNGDMSEFFRRFFGIPLPQAPGNGSGNGGNNPKNAPAPDNPPDTEQN
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASN
CCCCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECC
LPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGN
CCEEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCC
SGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAI
CCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEE
GEVTKDVADSIGLPKAEGALVSSVEPGGPADKAGIQPGDIILKFNGRSVDTASDLPRMVG
HHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHC
DTKPGAKATVSVWRKGQARDLPITIAETPAETTAKAEQRKNAPQKPRQTNSLGLTVSDLT
CCCCCCCEEHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHC
AEQMKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITNAKQFADVTAQLDPQKAV
HHHHHHHHHCCCCEEECCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHEE
AVLVRRGDNTQFVPVRPRQK
EEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]