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The map label for this gene is fabF [H]

Identifier: 78065709

GI number: 78065709

Start: 1171598

End: 1172830

Strand: Direct

Name: fabF [H]

Synonym: Bcep18194_A4237

Alternate gene names: 78065709

Gene position: 1171598-1172830 (Clockwise)

Preceding gene: 78065708

Following gene: 78065710

Centisome position: 31.72

GC content: 65.13

Gene sequence:

>1233_bases
GTGAGCCGCCGTCGTGTTGTTGTTACAGGCCTGGGGCTGATTTCGCCTGTTGGCAATAATGTTGCCGACGGCTGGGCCAA
TCTCGTCGCCGGCAAGTCCGGTATTGCCACCGTCACGAAGTTCGATCCGTCGAACCTCGCCGTCCACTTCGCAGGCGAAG
TGAAGGGTTTCGTTCCCGAGGAGTACATCCCGGCGAAGGAAGCCCGGAACATGGATACGTTCATCCATTACGGCATCGCC
GCCGGCGTCCAGGCTATCAAGGACAGCGGGCTGGAAGTGAACGAAGCCAATGCGGAACGCATCGGCGTGCTGGTCGGTTC
CGGCATCGGCGGCCTGCCGATGATCGAAGATACGCACCAGACCTACGTCGATCGCGGCGCGCGCCGGATTTCGCCGTTCT
TCGTGCCGGGTTCGATCATCAACATGATCTCGGGTCACCTGAGCATCATGTTCGGCCTGAAGGGCCCGAACCTCGCGGCC
GTGACGGCCTGCACGACCGGCCTGCACAGCATCGGCCTCGCAGCGCGCCTGATCCAGGCCGGCGATGCCGACGTGATGGT
CGCGGGCGGCGCCGAATCGACGGTGTCGCCGCTCGGCATCGGCGGCTTCGCGGCAGCGCGTGCGCTGTCGACCCGCAACG
ACGATCCGGCCAGCGCATCCCGTCCGTGGGACAAGGACCGCGACGGCTTCGTGCTGGGCGAGGGTGCCGGCGTGATGGTG
CTCGAAGAGTACGAAGCGGCGAAGGCGCGCGGTGCGAAGATCTACGCGGAAGTCTCGGGCTTCGGCATGACGGGCGACGC
GTACCACATGACCGCGCCGAACATGGACGGCCCGCGCCGTTGCATGGTCGCGGCACTGCGCGACGCCGGCGTGAACGCGG
ACGAGGTCCAGTACCTGAACGCGCACGGCACGTCGACGCCGCTGGGCGACAAGAACGAGTCGGACGCGGTGAAGGCGGCC
TTCGGCGAACACGCGTACAAGATCGTCGTGAACTCGACGAAGTCGATGACGGGCCACCTGCTGGGCGGCGCGGGCGGCCT
CGAATCGGTGTTCACGGTGCTGGCGCTGCACAACAACGTGTCGCCGCCGACCATCAACATCTTCAACCAGGACCCGGAGT
GCGATCTCGATTACTGCGCGAATACCGCGCGTGACATGAAGATCGACGTTGCCGTGAAGAACAACTTCGGCTTCGGCGGT
ACCAACGGCACGCTGGTGTTCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
TTCGCGCCGGACGGACTAACAGCCACAGGGCTCGCAGGGCTGGTTCCTGTGGCCACTGTGGCTTTTGTTTTTGTCATCCA
ATAATGGAAAAGAGGTTACC

Downstream 100 bases:

>100_bases
CGCCGCAATCGCTTGACGAGTCCATTCGATGCTCCGGCCGGGCGTCCGCAGCGTTTTGCGTTGCGGACCTCGGTCGTGTC
GTATTTCGTGCTGGCCGTGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFVPEEYIPAKEARNMDTFIHYGIA
AGVQAIKDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAA
VTACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPASASRPWDKDRDGFVLGEGAGVMV
LEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLNAHGTSTPLGDKNESDAVKAA
FGEHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKIDVAVKNNFGFGG
TNGTLVFKRV

Sequences:

>Translated_410_residues
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFVPEEYIPAKEARNMDTFIHYGIA
AGVQAIKDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAA
VTACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPASASRPWDKDRDGFVLGEGAGVMV
LEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLNAHGTSTPLGDKNESDAVKAA
FGEHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKIDVAVKNNFGFGG
TNGTLVFKRV
>Mature_409_residues
SRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFVPEEYIPAKEARNMDTFIHYGIAA
GVQAIKDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAV
TACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPASASRPWDKDRDGFVLGEGAGVMVL
EEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLNAHGTSTPLGDKNESDAVKAAF
GEHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKIDVAVKNNFGFGGT
NGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=46.875, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=50.6756756756757, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI41872631, Length=438, Percent_Identity=23.2876712328767, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=61.0169491525424, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI1788663, Length=411, Percent_Identity=38.4428223844282, Blast_Score=245, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=35.6796116504854, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=39.3939393939394, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI212642053, Length=367, Percent_Identity=24.2506811989101, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=413, Percent_Identity=23.9709443099274, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=455, Percent_Identity=35.8241758241758, Blast_Score=260, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24644341, Length=421, Percent_Identity=44.6555819477435, Blast_Score=337, Evalue=9e-93,
Organism=Drosophila melanogaster, GI19920632, Length=355, Percent_Identity=25.0704225352113, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI221330659, Length=355, Percent_Identity=25.0704225352113, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24581345, Length=428, Percent_Identity=22.4299065420561, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42828; Mature: 42697

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFVPE
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
EYIPAKEARNMDTFIHYGIAAGVQAIKDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQ
CCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCCCCCCHHH
TYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAVTACTTGLHSIGLAARLIQA
HHHHCCHHHCCCEECCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHC
GDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPASASRPWDKDRDGFVLGEGAGVMV
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLN
EECCHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEE
AHGTSTPLGDKNESDAVKAAFGEHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNV
CCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCC
SPPTINIFNQDPECDLDYCANTARDMKIDVAVKNNFGFGGTNGTLVFKRV
CCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFVPE
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
EYIPAKEARNMDTFIHYGIAAGVQAIKDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQ
CCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCCCCCCHHH
TYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAVTACTTGLHSIGLAARLIQA
HHHHCCHHHCCCEECCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHC
GDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPASASRPWDKDRDGFVLGEGAGVMV
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLN
EECCHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEE
AHGTSTPLGDKNESDAVKAAFGEHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNV
CCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCC
SPPTINIFNQDPECDLDYCANTARDMKIDVAVKNNFGFGGTNGTLVFKRV
CCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]