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The map label for this gene is pcaR [H]

Identifier: 78065381

GI number: 78065381

Start: 819903

End: 820694

Strand: Direct

Name: pcaR [H]

Synonym: Bcep18194_A3907

Alternate gene names: 78065381

Gene position: 819903-820694 (Clockwise)

Preceding gene: 78065379

Following gene: 78065382

Centisome position: 22.19

GC content: 70.45

Gene sequence:

>792_bases
ATGACACTTTCAACCATCGACGAAACCACGATCGACGAACGCAAGTTCGTCGTCGCGCTCGCGCGCGGGCTCGACCTGTT
GCGCGCATTCCGGCCCGGGGAGACGATGCTCGGCAACCGCGATTTCGCGGAGCGCACCGGGCTGCCGAAGGCAACCGTGA
ACCGGCTCGCCTACACGCTGACCGTGCTCGGCTACCTGCGCTATGACGAGACGCTCGGAAAGTATGCGCTCGACGCCGGC
GTGCTGTCGCTCGGCTACGCGCTGCTGTCGGGCTCGGGGACGATCGACCTCGCGCGGCCGCACATGCAGGCGCTCGCACG
CGACATCGGCGCGGCCGTGTCGCTCGGCTGCCGCGACGGGCTCGACATGATCTATCTGGAGACGATCCGCAGCGAGACGG
CGCTGACGCTCGGGCTCGCGCCCGGTTCGCGGCTGTCGATGCTGACGAGCTCGATGGGGCGTGCGTACCTGGCCGTGCAA
CCGGAGGACGTGCGCCGCGCGCTCTATGCGGAACTGCATCGCGCGGCCGGCGGCGCGGCCGACGCCGACGCGCTCGTCGC
CGCCGCGCAGCAGGCGGTGGCCGAGTTCTCGGCGGGCGGCTGCTGTTATTCGTTCCGGGCGTGGCACATGGACGTCAACG
CGGCGGCCGTACCGTTTCGCGAGCCGCGCGAGGGGCGCTGGCTGATCCTGAGCTGCAGCGGCCCCGCATCGTCGATGGAC
GAGGGTGTGTTCCGTACGCAGGTCGGGCCGAAGCTGAAGGCGCTCGCGCAGCGGCTCGGGCAGACGGCCTGA

Upstream 100 bases:

>100_bases
CGGTCCCTGATTCAGCCGGGTTCCATGCCTGAGAGTTTGCTTGACGGAAGTTCCGCTGTGCGGAACAATGTTTTGCAAAT
CGAACCCAGTGTAGCACCAG

Downstream 100 bases:

>100_bases
GCGAAGCGCGCGAGCGGTAGGGGGCCGTCACCGGCTCGGGTGAAAACGCACGAGCGCGACACGGCCGCGGCCGGTTGTGC
CACCGGCGAACCGCGCGCAT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGSGTIDLARPHMQALARDIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PEDVRRALYAELHRAAGGAADADALVAAAQQAVAEFSAGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
EGVFRTQVGPKLKALAQRLGQTA

Sequences:

>Translated_263_residues
MTLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGSGTIDLARPHMQALARDIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PEDVRRALYAELHRAAGGAADADALVAAAQQAVAEFSAGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
EGVFRTQVGPKLKALAQRLGQTA
>Mature_262_residues
TLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAGV
LSLGYALLSGSGTIDLARPHMQALARDIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQP
EDVRRALYAELHRAAGGAADADALVAAAQQAVAEFSAGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMDE
GVFRTQVGPKLKALAQRLGQTA

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=230, Percent_Identity=25.6521739130435, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28150; Mature: 28018

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGSGTIDLARPHMQALARDIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPEDVRRALYAELHRAAGGAA
CHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DADALVAAAQQAVAEFSAGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
CHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCEECCCCCCCCCCEEEEECCCCCCHHH
EGVFRTQVGPKLKALAQRLGQTA
CCHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGSGTIDLARPHMQALARDIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPEDVRRALYAELHRAAGGAA
CHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DADALVAAAQQAVAEFSAGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
CHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCEECCCCCCCCCCEEEEECCCCCCHHH
EGVFRTQVGPKLKALAQRLGQTA
CCHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]