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The map label for this gene is alsR [H]

Identifier: 78065200

GI number: 78065200

Start: 613467

End: 614369

Strand: Reverse

Name: alsR [H]

Synonym: Bcep18194_A3724

Alternate gene names: 78065200

Gene position: 614369-613467 (Counterclockwise)

Preceding gene: 78065205

Following gene: 161702968

Centisome position: 16.63

GC content: 70.65

Gene sequence:

>903_bases
ATGGAACTCAAGCAATTGCGCGCCTTCGTCACGCTCGCGGAAGAGCTGCATTTCGGGCGCGCCGCGCAGCGCCTGTTCAT
CGTGCAGCCCGCGCTGAGCATGCAGATCAAGGCGCTCGAGGAAGAACTCGGCGCGCGCCTGTTCGAGCGCGACCGGCACA
AGGTCGAACTGAGCGATACGGGGCGCGTGTTCCTGCCCGAGGCGCGCGCCACGCTGCAGCAGGCCGCCCGCGCGGAACAG
ATGGCGCGGCTGTCGAGCCGCGGCGAGATCGGCACGCTGCGGATCGCGTTCGTGTCGTCGGTACTGCCCGTGCTGCTGCC
GGCCGTGCTGCGCACGATGCGCGAGCGCTATCCGCTGATCACGCTCGAACTGAAGGACCTGCCGACGCCCGACCAGATCG
CCGCGCTACGCGACCGGCGGATCGATTTCGGGATGATCCGGCTGCCGGCCGCGTATGCGGGCATCGACACGCGCGTGGTG
CTCGAAGAAGGTTTCGTCGTCGCGCTGCCGCTCGACCACCCGCTCGCCGCGCACGATGCGATCTCGCCGGCCGCGCTGCG
CGGCCAGCCCGCGTTCGTGCTCGCGCGCCGCTACGCGCCGGGCTTTCACGACGACATGCTGCTCGCGCTGAGCCGCGCGG
GCACGACGCTCGAGATCGCGCAGGAGTTCGGGGAGTTCACGACGATGCTCGCGCTCGTCGCGGCGGGGATGGGCATCGGG
CTGATTCCGGCGGAGGCCGCCAGCGCGCTGCCGCCGAACGTGCTCGCGCGGCCGCTCGACCTGGCCGGCCACCGAACGGG
TATCGGCCTCGCGTGGACCGACCTCGACAGCCCGCTGAAGCGCGCGTTCGTCGCCGCACTCGAGCAGGTGACGGCAGCAT
CGAGCAACAACGGCGGGCAATAA

Upstream 100 bases:

>100_bases
GTTGACGGTATCTTCGGCCGCCGGCCGGGCGCTGCGCCAATGGTCTTTTTTGATCCGGTTATCATGAAACCTGATCACCG
CCCTCTCCTGCCCGCCGCCC

Downstream 100 bases:

>100_bases
CTGCAGGCAATTAAAAAGCCCGGCCGGAAAACCGGGCCGGGCTCGTTCGCTACGCCGGCCGCCTTGCGGCAGCCGCGCAA
CGTGCGGGATTACTTCGCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MELKQLRAFVTLAEELHFGRAAQRLFIVQPALSMQIKALEEELGARLFERDRHKVELSDTGRVFLPEARATLQQAARAEQ
MARLSSRGEIGTLRIAFVSSVLPVLLPAVLRTMRERYPLITLELKDLPTPDQIAALRDRRIDFGMIRLPAAYAGIDTRVV
LEEGFVVALPLDHPLAAHDAISPAALRGQPAFVLARRYAPGFHDDMLLALSRAGTTLEIAQEFGEFTTMLALVAAGMGIG
LIPAEAASALPPNVLARPLDLAGHRTGIGLAWTDLDSPLKRAFVAALEQVTAASSNNGGQ

Sequences:

>Translated_300_residues
MELKQLRAFVTLAEELHFGRAAQRLFIVQPALSMQIKALEEELGARLFERDRHKVELSDTGRVFLPEARATLQQAARAEQ
MARLSSRGEIGTLRIAFVSSVLPVLLPAVLRTMRERYPLITLELKDLPTPDQIAALRDRRIDFGMIRLPAAYAGIDTRVV
LEEGFVVALPLDHPLAAHDAISPAALRGQPAFVLARRYAPGFHDDMLLALSRAGTTLEIAQEFGEFTTMLALVAAGMGIG
LIPAEAASALPPNVLARPLDLAGHRTGIGLAWTDLDSPLKRAFVAALEQVTAASSNNGGQ
>Mature_300_residues
MELKQLRAFVTLAEELHFGRAAQRLFIVQPALSMQIKALEEELGARLFERDRHKVELSDTGRVFLPEARATLQQAARAEQ
MARLSSRGEIGTLRIAFVSSVLPVLLPAVLRTMRERYPLITLELKDLPTPDQIAALRDRRIDFGMIRLPAAYAGIDTRVV
LEEGFVVALPLDHPLAAHDAISPAALRGQPAFVLARRYAPGFHDDMLLALSRAGTTLEIAQEFGEFTTMLALVAAGMGIG
LIPAEAASALPPNVLARPLDLAGHRTGIGLAWTDLDSPLKRAFVAALEQVTAASSNNGGQ

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=39.6, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788887, Length=292, Percent_Identity=35.2739726027397, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI2367136, Length=264, Percent_Identity=32.9545454545455, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI145693105, Length=250, Percent_Identity=30.8, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=29.4314381270903, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI157672245, Length=245, Percent_Identity=26.9387755102041, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787530, Length=274, Percent_Identity=27.7372262773723, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788481, Length=242, Percent_Identity=28.5123966942149, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87081904, Length=210, Percent_Identity=28.0952380952381, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787806, Length=276, Percent_Identity=26.4492753623188, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787601, Length=179, Percent_Identity=28.4916201117318, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788296, Length=254, Percent_Identity=28.3464566929134, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994962, Length=93, Percent_Identity=37.6344086021505, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=142, Percent_Identity=30.2816901408451, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790208, Length=257, Percent_Identity=27.2373540856031, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789173, Length=148, Percent_Identity=30.4054054054054, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32564; Mature: 32564

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKQLRAFVTLAEELHFGRAAQRLFIVQPALSMQIKALEEELGARLFERDRHKVELSDT
CCHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GRVFLPEARATLQQAARAEQMARLSSRGEIGTLRIAFVSSVLPVLLPAVLRTMRERYPLI
CCEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
TLELKDLPTPDQIAALRDRRIDFGMIRLPAAYAGIDTRVVLEEGFVVALPLDHPLAAHDA
EEEECCCCCHHHHHHHHHCCCCCCEEECCHHHHCCCEEEEEECCEEEEEECCCCCHHHCC
ISPAALRGQPAFVLARRYAPGFHDDMLLALSRAGTTLEIAQEFGEFTTMLALVAAGMGIG
CCCHHHCCCCHHEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LIPAEAASALPPNVLARPLDLAGHRTGIGLAWTDLDSPLKRAFVAALEQVTAASSNNGGQ
CCCHHHHHCCCHHHHHCCHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELKQLRAFVTLAEELHFGRAAQRLFIVQPALSMQIKALEEELGARLFERDRHKVELSDT
CCHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GRVFLPEARATLQQAARAEQMARLSSRGEIGTLRIAFVSSVLPVLLPAVLRTMRERYPLI
CCEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
TLELKDLPTPDQIAALRDRRIDFGMIRLPAAYAGIDTRVVLEEGFVVALPLDHPLAAHDA
EEEECCCCCHHHHHHHHHCCCCCCEEECCHHHHCCCEEEEEECCEEEEEECCCCCHHHCC
ISPAALRGQPAFVLARRYAPGFHDDMLLALSRAGTTLEIAQEFGEFTTMLALVAAGMGIG
CCCHHHCCCCHHEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LIPAEAASALPPNVLARPLDLAGHRTGIGLAWTDLDSPLKRAFVAALEQVTAASSNNGGQ
CCCHHHHHCCCHHHHHCCHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]