| Definition | Burkholderia sp. 383 chromosome 1, complete genome. |
|---|---|
| Accession | NC_007510 |
| Length | 3,694,126 |
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The map label for this gene is secA [H]
Identifier: 78065130
GI number: 78065130
Start: 539581
End: 542379
Strand: Direct
Name: secA [H]
Synonym: Bcep18194_A3654
Alternate gene names: 78065130
Gene position: 539581-542379 (Clockwise)
Preceding gene: 78065128
Following gene: 78065131
Centisome position: 14.61
GC content: 64.74
Gene sequence:
>2799_bases ATGACAACCGGTTTTCTCCAGAAAATTTTTGGCAGCCGCAACCAGCGGCTCGTCAAGCAATACCAAAAGACCGTCACGAC GATCAATGCGCTCGAAACGCAGATCGAGAAGCTGACGGACGACCAGTTGCGCGGCAAGACGGACGAATTCCGCCAGCGGG TCGCGGCCGGCGAGTCGCTCGACAAGCTGCTGCCCGAGGCTTTCGCGGTGTGTCGCGAGGCCAGCCGTCGCGTGCTGAAG ATGCGGCACTTCGACGTGCAGATGATCGGCGGCATGGTGCTCCACTACGGCAAGATCGCGGAAATGCGCACCGGCGAGGG CAAGACGCTCGTCGCGACGCTGCCCGTGTACCTGAACGCGCTGGCAGGCCGCGGCGTGCACGTGGTGACCGTCAACGATT ACCTCGCGCAGCGCGACGCCGAATGGATGGCGCGCCTCTACAACTTCCTCGGTCTGTCGGTCGGCATCAACCTGTCCGGC ATGGAGCACGACCAGAAGCAGCAGGCCTACGCGGCGGACATCACGTACGGCACGAACAACGAATTCGGCTTCGACTACCT GCGCGACAACATGGTCTACGAGACCGACGCGCGCGTGCAGCGGGCACTGAACTTCGCGGTCGTCGACGAAGTGGACTCGA TCCTGATCGACGAGGCACGCACGCCGCTGATCATTTCGGGCCAGGCCGAGGATCACACCGAGCTGTACGTGCGGATGAAC GCACTGCCGCCGCTGCTCGAGCGCCAGATCGGTGAAGAGAAGGCCGACGGCACGGGCGTCGAGAAGCCGGGCGACTACAC GCTCGACGAGAAGGCACGCCAGGTGTTCCTGACGGAATCGGGCCACGAAAAGGCCGAGCGCCTGCTCGCTGAATGGGGCC TGATCGGCGAGGGCGAGAGCCTGTACGCGCCGCAGAACATCACGCTGATGCACCACGTGTACGCGGCACTGCGCGCACAC ACGCTGTTCCACAAGGATCAGCACTACGTCGTGCAGAACGGCGAAGTGGTCATCGTCGACGAATTCACGGGCCGCCTGAT GGCCGGCCGCCGCTGGTCCGACGGCCTGCACCAGGCGGTCGAGGCGAAGGAGCACGTGAAGATCCAGAGCGAGAACCAGA CGCTCGCGTCGATCACGTTCCAGAACTACTTCCGGATGTACGCGAAGCTGGCCGGCATGACCGGTACCGCCGACACCGAA GCGTACGAATTCAACGAGATCTACGGCCTCGAGACGGTCGTGATCCCGACCAACCGTCCGCCGAAGCGGATCGACAAGCA GGACCAGATCTACAAGACGGCCAAGGAGCGCTATGACGCGGTGATCCGCGACATTCGCGACTGCTACGAGCGTGGCCAGC CGGTGCTGGTCGGCACGACGTCGATCGAGAACTCCGAGCTGCTGTCGCACCTGCTGAAGCAGGCCGGGTTGCCGCATGAG GTGCTGAACGCGAAGCAGCACGAGCGCGAAGCCGCGATCGTCGCGGAAGCCGGCCGTCCGAAGCGCGTCACGATCGCAAC CAACATGGCCGGTCGCGGTACCGACATCGTGCTCGGTGGCAATGCCGAGAAGCAGGCCGCGTTCATCGAAGCCGACGAAG CAATTCCCGCCGACGAAAAGGCGCGCCGCATCCAGCAACTGCACGACGAGTGGGAAACGCTGCACGAGCAGGTGAAGGCC GCGGGCGGCCTGCACATCATCGGTACCGAGCGCCATGAATCGCGCCGGATCGACAACCAGCTGCGCGGCCGTGCGGGCCG CCAGGGCGATCCGGGCTCGTCGCGCTTCTACCTGTCGCTCGACGATCCGCTTCTGCGTATCTTCGCGGGCGACCGCGTGC GTTCGATCATGGACCGCCTGAAGATGCCGGAAGGCGAGGCGATCGAGGCCGGCATCGTCACGCGCTCGATCGAATCCGCG CAGCGCAAGGTCGAAGCGCGCAACTTCGACATCCGCAAGCAGCTGCTCGAATACGACGACGTGTCGAACGACCAGCGCAA GGTGATCTACCAGCAGCGTAACGAGCTGCTCGAAGCGCACGACATCACCGAGACGATCACCGCGATGCGTCATGGCGTCG TGACCGAAGTCGTCCGCCAGTTCGTGCCGGAAGGCAGCATCGAAGAGCAGTGGGACGTGCCCGAGCTCGAGGAAGCGCTG CGCAACGACTGGCAGCTCGACCTCGCGATCCAGGAAATGGTGAACGAGTCGTCGTCGATCACGGCCGAGGAGATCCTCGA CGCGGTGATGACGGCCGCCGACGAGCAGTACGAGGCGAAGGTCGCGATGGTCGGCCGCGAATCGTTCAGCGCGTTCGAGC GCTCGGTAATGCTGCAGACGGTCGACCGCCTGTGGCGCGAGCACCTCGCGGCGCTCGACCACCTGCGCCAGGGCATCCAC CTGCGCGGCTATGCGCAGAAGAATCCGAAGCAGGAATACAAGCGCGAAGCGTTCGAGCTGTTCGCCGCGATGCTCGAGGC GATCAAGCAGGAAGTCACGCGCGTCGTGATGAACGTGCAGATCCAGTCGCCGGAACAGCTCGAGCAAGCCGCCGAGCAGA TCGAGGAGCGTGGCGGTCATCTCGAGAACGTCGAGTACCAGCACGCCGATTACGCGGAAGCCGGTGCGCCGGTGGCGAAC GTCGCGGTTGCCGCGGCGGCCACCGCGACGGCCGACATGGTCGGCAGCGCGATGACGCACAGCGGCCCCGGCGGCGAAAT GCCGAAGGTCGGTCGCAACGACCCGTGCCCGTGCGGCAGCGGCAAGAAGTACAAGCAGTGTCACGGGAAGCTGTCATGA
Upstream 100 bases:
>100_bases TCCTCGTTTGAGTCCACTAATTCGCTAAGCCGCCGAGGCTCGGGCGTCGGGGCGCGCAACACGCGCCGGGCGCCGGTGCT GCGACGCAGGATCCGATCCG
Downstream 100 bases:
>100_bases TCGACGGCGGCGCGCGTCACGCGTGCCGCTTCGTTTGCAGCTTCGAGTGAGTAATGTGAGTTGCGGCGGCCCGCGCGTGC GGCCGCCGGTTCTTCCAATC
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 932; Mature: 931
Protein sequence:
>932_residues MTTGFLQKIFGSRNQRLVKQYQKTVTTINALETQIEKLTDDQLRGKTDEFRQRVAAGESLDKLLPEAFAVCREASRRVLK MRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLPVYLNALAGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSG MEHDQKQQAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN ALPPLLERQIGEEKADGTGVEKPGDYTLDEKARQVFLTESGHEKAERLLAEWGLIGEGESLYAPQNITLMHHVYAALRAH TLFHKDQHYVVQNGEVVIVDEFTGRLMAGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLAGMTGTADTE AYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE VLNAKQHEREAAIVAEAGRPKRVTIATNMAGRGTDIVLGGNAEKQAAFIEADEAIPADEKARRIQQLHDEWETLHEQVKA AGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLDDPLLRIFAGDRVRSIMDRLKMPEGEAIEAGIVTRSIESA QRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDITETITAMRHGVVTEVVRQFVPEGSIEEQWDVPELEEAL RNDWQLDLAIQEMVNESSSITAEEILDAVMTAADEQYEAKVAMVGRESFSAFERSVMLQTVDRLWREHLAALDHLRQGIH LRGYAQKNPKQEYKREAFELFAAMLEAIKQEVTRVVMNVQIQSPEQLEQAAEQIEERGGHLENVEYQHADYAEAGAPVAN VAVAAAATATADMVGSAMTHSGPGGEMPKVGRNDPCPCGSGKKYKQCHGKLS
Sequences:
>Translated_932_residues MTTGFLQKIFGSRNQRLVKQYQKTVTTINALETQIEKLTDDQLRGKTDEFRQRVAAGESLDKLLPEAFAVCREASRRVLK MRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLPVYLNALAGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSG MEHDQKQQAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN ALPPLLERQIGEEKADGTGVEKPGDYTLDEKARQVFLTESGHEKAERLLAEWGLIGEGESLYAPQNITLMHHVYAALRAH TLFHKDQHYVVQNGEVVIVDEFTGRLMAGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLAGMTGTADTE AYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE VLNAKQHEREAAIVAEAGRPKRVTIATNMAGRGTDIVLGGNAEKQAAFIEADEAIPADEKARRIQQLHDEWETLHEQVKA AGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLDDPLLRIFAGDRVRSIMDRLKMPEGEAIEAGIVTRSIESA QRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDITETITAMRHGVVTEVVRQFVPEGSIEEQWDVPELEEAL RNDWQLDLAIQEMVNESSSITAEEILDAVMTAADEQYEAKVAMVGRESFSAFERSVMLQTVDRLWREHLAALDHLRQGIH LRGYAQKNPKQEYKREAFELFAAMLEAIKQEVTRVVMNVQIQSPEQLEQAAEQIEERGGHLENVEYQHADYAEAGAPVAN VAVAAAATATADMVGSAMTHSGPGGEMPKVGRNDPCPCGSGKKYKQCHGKLS >Mature_931_residues TTGFLQKIFGSRNQRLVKQYQKTVTTINALETQIEKLTDDQLRGKTDEFRQRVAAGESLDKLLPEAFAVCREASRRVLKM RHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLPVYLNALAGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSGM EHDQKQQAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNA LPPLLERQIGEEKADGTGVEKPGDYTLDEKARQVFLTESGHEKAERLLAEWGLIGEGESLYAPQNITLMHHVYAALRAHT LFHKDQHYVVQNGEVVIVDEFTGRLMAGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLAGMTGTADTEA YEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHEV LNAKQHEREAAIVAEAGRPKRVTIATNMAGRGTDIVLGGNAEKQAAFIEADEAIPADEKARRIQQLHDEWETLHEQVKAA GGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLDDPLLRIFAGDRVRSIMDRLKMPEGEAIEAGIVTRSIESAQ RKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDITETITAMRHGVVTEVVRQFVPEGSIEEQWDVPELEEALR NDWQLDLAIQEMVNESSSITAEEILDAVMTAADEQYEAKVAMVGRESFSAFERSVMLQTVDRLWREHLAALDHLRQGIHL RGYAQKNPKQEYKREAFELFAAMLEAIKQEVTRVVMNVQIQSPEQLEQAAEQIEERGGHLENVEYQHADYAEAGAPVANV AVAAAATATADMVGSAMTHSGPGGEMPKVGRNDPCPCGSGKKYKQCHGKLS
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=934, Percent_Identity=59.4218415417559, Blast_Score=1098, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 104807; Mature: 104675
Theoretical pI: Translated: 5.29; Mature: 5.29
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTGFLQKIFGSRNQRLVKQYQKTVTTINALETQIEKLTDDQLRGKTDEFRQRVAAGESL CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCHH DKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLPVYLNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHH LAGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSGMEHDQKQQAYAADITYGTNN HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEEEECCCC EFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN CCCHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEC ALPPLLERQIGEEKADGTGVEKPGDYTLDEKARQVFLTESGHEKAERLLAEWGLIGEGES CCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHEEEECCCCHHHHHHHHHHHCCCCCCCC LYAPQNITLMHHVYAALRAHTLFHKDQHYVVQNGEVVIVDEFTGRLMAGRRWSDGLHQAV EECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCHHHCCCCCHHHHHHHH EAKEHVKIQSENQTLASITFQNYFRMYAKLAGMTGTADTEAYEFNEIYGLETVVIPTNRP HHHHHCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCEEEEECCCCC PKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH VLNAKQHEREAAIVAEAGRPKRVTIATNMAGRGTDIVLGGNAEKQAAFIEADEAIPADEK HHCCHHHHHHHHHEECCCCCCEEEEEECCCCCCCEEEECCCCCHHHHEEECCCCCCCHHH ARRIQQLHDEWETLHEQVKAAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSL HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE DDPLLRIFAGDRVRSIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDD CCHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC VSNDQRKVIYQQRNELLEAHDITETITAMRHGVVTEVVRQFVPEGSIEEQWDVPELEEAL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH RNDWQLDLAIQEMVNESSSITAEEILDAVMTAADEQYEAKVAMVGRESFSAFERSVMLQT HCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH VDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLEAIKQEVTRVVMNVQ HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC IQSPEQLEQAAEQIEERGGHLENVEYQHADYAEAGAPVANVAVAAAATATADMVGSAMTH CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC SGPGGEMPKVGRNDPCPCGSGKKYKQCHGKLS CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC >Mature Secondary Structure TTGFLQKIFGSRNQRLVKQYQKTVTTINALETQIEKLTDDQLRGKTDEFRQRVAAGESL CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCHH DKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLPVYLNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHH LAGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSGMEHDQKQQAYAADITYGTNN HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEEEECCCC EFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN CCCHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEC ALPPLLERQIGEEKADGTGVEKPGDYTLDEKARQVFLTESGHEKAERLLAEWGLIGEGES CCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHEEEECCCCHHHHHHHHHHHCCCCCCCC LYAPQNITLMHHVYAALRAHTLFHKDQHYVVQNGEVVIVDEFTGRLMAGRRWSDGLHQAV EECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCHHHCCCCCHHHHHHHH EAKEHVKIQSENQTLASITFQNYFRMYAKLAGMTGTADTEAYEFNEIYGLETVVIPTNRP HHHHHCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCEEEEECCCCC PKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH VLNAKQHEREAAIVAEAGRPKRVTIATNMAGRGTDIVLGGNAEKQAAFIEADEAIPADEK HHCCHHHHHHHHHEECCCCCCEEEEEECCCCCCCEEEECCCCCHHHHEEECCCCCCCHHH ARRIQQLHDEWETLHEQVKAAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSL HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE DDPLLRIFAGDRVRSIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDD CCHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC VSNDQRKVIYQQRNELLEAHDITETITAMRHGVVTEVVRQFVPEGSIEEQWDVPELEEAL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH RNDWQLDLAIQEMVNESSSITAEEILDAVMTAADEQYEAKVAMVGRESFSAFERSVMLQT HCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH VDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLEAIKQEVTRVVMNVQ HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC IQSPEQLEQAAEQIEERGGHLENVEYQHADYAEAGAPVANVAVAAAATATADMVGSAMTH CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC SGPGGEMPKVGRNDPCPCGSGKKYKQCHGKLS CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA