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The map label for this gene is degQ [H]

Identifier: 78065014

GI number: 78065014

Start: 399419

End: 400624

Strand: Reverse

Name: degQ [H]

Synonym: Bcep18194_A3537

Alternate gene names: 78065014

Gene position: 400624-399419 (Counterclockwise)

Preceding gene: 78065021

Following gene: 78064984

Centisome position: 10.84

GC content: 66.75

Gene sequence:

>1206_bases
ATGCTTAGACGCTTCTGGCTGTTCTTCGCGCAGGCGGTTACCGTGCTGCTCGCGCTGATGTTCATCGTCGTGACGCTCAA
GCCGCAATGGCTGCAACGGCAAGGACAGCTCGGCAAGCAGCTCGCCACGCCGATCGTTGCGCTGCGGGAAGTCGCGCCGG
GCATCGGCGGGGCGCCGGCGACCACGTCGTACGCCGAAGCCGCGCAGAAGGCGATGCCGGCCGTCGTCAACGTCTTCTCC
AGCAAGGACGGCTCGCTGCCGCCCGACCCACGCGCGAAAGATCCGCTGTTCCGCTACTTCTTCGGCGACCGCAACGCCCG
CAAGCAGCAGGACGAACCGGCCGCCAACCTTGGCTCGGGCGTTATCGTGAGCCCTGAAGGTTACATTCTAACGAACCAGC
ACGTCGTGGACGGCGCCGACCAGATCGAAGTCGCGCTCGCCGACGGCCGCACGGCCACCGCGAAGGTGATCGGCAGCGAT
CCCGAAACCGATCTCGCCGTGCTGAAGATCAACATGACGAACCTGCCGACGATCACGCTCGGCCGCTCCGACCAGTCGCG
GGTCGGCGACGTCGTGCTCGCGATCGGCAACCCGTTCGGCGTCGGCCAGACGGTCACGATGGGGATCATCAGCGCGCTCG
GCCGCAATCACCTCGGCATCAACACGTTCGAGAACTTCATCCAGACCGACGCACCGATCAACCCCGGCAACTCGGGCGGC
GCGCTGGTCGACGTGAACGGCAACCTGCTCGGCATCAACACGGCGATCTACTCGCGCTCGGGCGGCTCGCTCGGCATCGG
CTTCGCGATTCCCGTATCGACTGCGCGCACGGTGCTGGAAAGCATCATCACGTCCGGCTCGGTCACGCGCGGCTGGATCG
GCGTCGAGCCGCAGGACGTCACGCCGGAGATCGCCGAGTCGTTCGGGCTGTCGCAGAAATCAGGCGCGATCGTCGCCGGC
GTGCTGCAGGGCGGCCCGGCCGACAAGGCCGGCATCAAGCCGGGCGACATCCTGGTCTCGGTCAACGGCGACGAGATCAC
CGACACGACGAAGCTGCTGAACACCGTCGCGCAGATCAAGCCCGGCACGCCGACCAAGGTGCACGTCGTGCGCAAGGGCA
AGGAGTTCGACGTGAACGTGGTGATCGGCAAGCGCCCGCCGCCGCCGAAGCAGGCGCTCGACGAGCAGGACAGCGATACC
GAGTGA

Upstream 100 bases:

>100_bases
GGCCATTCGGGCAATAGTCCTTGAAGCGCGCGGTTTCAAGGGTATTGTTCAAGTACAATTCAAGTTCGATCCGATCCATA
TAAACCTCTAATCCATTCAG

Downstream 100 bases:

>100_bases
CGTCGGGCGCGCAGCGCCGAGCCGCATGCCGGACACCGTCGGAAATGAAAAAGGGCAGCCGGTTGGCTGCCCTTTTGCTT
TGCATCGAAAGTCTCGTTGC

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPATTSYAEAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSGVIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITSGSVTRGWIGVEPQDVTPEIAESFGLSQKSGAIVAG
VLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIKPGTPTKVHVVRKGKEFDVNVVIGKRPPPPKQALDEQDSDT
E

Sequences:

>Translated_401_residues
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPATTSYAEAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSGVIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITSGSVTRGWIGVEPQDVTPEIAESFGLSQKSGAIVAG
VLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIKPGTPTKVHVVRKGKEFDVNVVIGKRPPPPKQALDEQDSDT
E
>Mature_401_residues
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPATTSYAEAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSGVIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITSGSVTRGWIGVEPQDVTPEIAESFGLSQKSGAIVAG
VLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIKPGTPTKVHVVRKGKEFDVNVVIGKRPPPPKQALDEQDSDT
E

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=354, Percent_Identity=33.6158192090396, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=35.0393700787402, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI7019477, Length=287, Percent_Identity=35.8885017421603, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI22129776, Length=264, Percent_Identity=35.9848484848485, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1789629, Length=326, Percent_Identity=45.398773006135, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI1786356, Length=343, Percent_Identity=42.5655976676385, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1789630, Length=328, Percent_Identity=42.6829268292683, Blast_Score=228, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24646839, Length=284, Percent_Identity=35.2112676056338, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 42100; Mature: 42100

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TTSYAEAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHCCCC
VIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSDPETDLAVLKINMTNLPTITL
EEECCCCEEEECCEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCEEEE
GRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITSGSVTRGWIGVEPQDV
EEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCEECCCCCCC
TPEIAESFGLSQKSGAIVAGVLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIK
CHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PGTPTKVHVVRKGKEFDVNVVIGKRPPPPKQALDEQDSDTE
CCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TTSYAEAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHCCCC
VIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSDPETDLAVLKINMTNLPTITL
EEECCCCEEEECCEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCEEEE
GRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITSGSVTRGWIGVEPQDV
EEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCEECCCCCCC
TPEIAESFGLSQKSGAIVAGVLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIK
CHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PGTPTKVHVVRKGKEFDVNVVIGKRPPPPKQALDEQDSDTE
CCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]