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The map label for this gene is paaE [H]

Identifier: 78064902

GI number: 78064902

Start: 287485

End: 288573

Strand: Reverse

Name: paaE [H]

Synonym: Bcep18194_A3425

Alternate gene names: 78064902

Gene position: 288573-287485 (Counterclockwise)

Preceding gene: 78064903

Following gene: 78064901

Centisome position: 7.81

GC content: 66.39

Gene sequence:

>1089_bases
ATGGCGACCCCGCAATTTCATCCGCTGCGTATCCGCGACGTGCGGCCCGAGACCGCCGACGCCGTAACCGTCTCCTTCGA
CGTGCCGCCCGAGCTGCGCGATGCGTACCGCTTCACGCAGGGCCAGTTCGTCACGCTGAAGACCCACATCGACGGCGAGG
AAACGCGCCGCTCGTATTCGATCTGCGTCGGCACGACGGACTACGACCGTGACGGCGAACTGCGCATCGGCATCAAGCGC
GTGCGCGGCGGCCGCTTCTCGAACTTCGCGTTCGACTCGCTCCAGCCGGGCCACACGATCGACGTGATGACGCCGGACGG
CCGTTTCTTCACGCACCTGAACGCCGATCACGGCAAGCAGTACGTCGCGTTTTCCGGCGGCTCCGGGATCACGCCGGTGC
TCGCGATCGTGAAGACGACGCTCGAACTCGAACCGCGCAGCACGTTCACGCTGATCTACGGCAACCGCAGCGTCGACGCG
ATCATGTTCGCGGAGGAGCTCGAGGACCTGAAGAACCGCTACATGAACCGCTTCGTCCTCTATCACGTGCTGTCGGACGA
CCAGCAGGACGTCGAGCTGTTCAACGGCGTGCTCGACCAGACGAAATGCGCGGAATTCCTCGGCACGCTGACGCCGGCCG
ACGCGATCGACGAGGCTTTCATCTGCGGCCCCGCGCCGATGATGGATGCGGCCGAGGCCGCGCTGAAGGCGGCCGGCGTG
CCGCAGGCGAAGGTGCACGTCGAGCGCTTCGGCACGCCGCTGCCGCAGGCCGGCGCGCCGGTCGTCGAAATCACCGACCA
GACGCCGGCCGCCGACCTGGAAATCGTGCTCGACGGCAAGAAGCGCAAGCTGCGGCTGCCGTACGAAGGCGTGAGCCTGC
TCGATGTCGGCCTGCGCGCGGGCCTCGCGCTGCCGTACGCGTGCAAGGGCGGCGTGTGCTGCACGTGCCGTGCGAAGGTG
CTCGAGGGCGAAGTGCGGATGGAGAAGAACTACACGCTCGAAGAGCATGAAGTGAAGGACGGCTTCGTGCTCACGTGCCA
GTGCCACCCGATCAGCGACAAGGTCGTCGTGAGCTACGACGAGCGTTGA

Upstream 100 bases:

>100_bases
CCGAACGTCTCGCGCAATTCGCGTCCACGGCCTGCAAGGCGCTGTATCGCTGCGTCGACTGCCGCGAACCCTTCGACTAC
TTCAAACCTTATTAATCGAT

Downstream 100 bases:

>100_bases
GCGACGTCGCGTCGCGGTGCCGGACGGTTTCTCGCCGTCACACATCTCGCTTACACTAGGGGCCGCCGGCCGGCTGGACA
TCGCAACGTCCGCCCGGCCG

Product: phenylacetate-CoA oxygenase/reductase, PaaK subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MATPQFHPLRIRDVRPETADAVTVSFDVPPELRDAYRFTQGQFVTLKTHIDGEETRRSYSICVGTTDYDRDGELRIGIKR
VRGGRFSNFAFDSLQPGHTIDVMTPDGRFFTHLNADHGKQYVAFSGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDA
IMFAEELEDLKNRYMNRFVLYHVLSDDQQDVELFNGVLDQTKCAEFLGTLTPADAIDEAFICGPAPMMDAAEAALKAAGV
PQAKVHVERFGTPLPQAGAPVVEITDQTPAADLEIVLDGKKRKLRLPYEGVSLLDVGLRAGLALPYACKGGVCCTCRAKV
LEGEVRMEKNYTLEEHEVKDGFVLTCQCHPISDKVVVSYDER

Sequences:

>Translated_362_residues
MATPQFHPLRIRDVRPETADAVTVSFDVPPELRDAYRFTQGQFVTLKTHIDGEETRRSYSICVGTTDYDRDGELRIGIKR
VRGGRFSNFAFDSLQPGHTIDVMTPDGRFFTHLNADHGKQYVAFSGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDA
IMFAEELEDLKNRYMNRFVLYHVLSDDQQDVELFNGVLDQTKCAEFLGTLTPADAIDEAFICGPAPMMDAAEAALKAAGV
PQAKVHVERFGTPLPQAGAPVVEITDQTPAADLEIVLDGKKRKLRLPYEGVSLLDVGLRAGLALPYACKGGVCCTCRAKV
LEGEVRMEKNYTLEEHEVKDGFVLTCQCHPISDKVVVSYDER
>Mature_361_residues
ATPQFHPLRIRDVRPETADAVTVSFDVPPELRDAYRFTQGQFVTLKTHIDGEETRRSYSICVGTTDYDRDGELRIGIKRV
RGGRFSNFAFDSLQPGHTIDVMTPDGRFFTHLNADHGKQYVAFSGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDAI
MFAEELEDLKNRYMNRFVLYHVLSDDQQDVELFNGVLDQTKCAEFLGTLTPADAIDEAFICGPAPMMDAAEAALKAAGVP
QAKVHVERFGTPLPQAGAPVVEITDQTPAADLEIVLDGKKRKLRLPYEGVSLLDVGLRAGLALPYACKGGVCCTCRAKVL
EGEVRMEKNYTLEEHEVKDGFVLTCQCHPISDKVVVSYDER

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI49574502, Length=216, Percent_Identity=28.7037037037037, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1787658, Length=357, Percent_Identity=45.6582633053221, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1787098, Length=350, Percent_Identity=24.8571428571429, Blast_Score=111, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6322146, Length=220, Percent_Identity=25.9090909090909, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40053; Mature: 39922

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPQFHPLRIRDVRPETADAVTVSFDVPPELRDAYRFTQGQFVTLKTHIDGEETRRSYS
CCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEEEEECCCHHHCCEEE
ICVGTTDYDRDGELRIGIKRVRGGRFSNFAFDSLQPGHTIDVMTPDGRFFTHLNADHGKQ
EEEECCCCCCCCCEEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCEEEEECCCCCCE
YVAFSGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDAIMFAEELEDLKNRYMNRFVL
EEEEECCCCCHHHHHHHHHHEEECCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHEEE
YHVLSDDQQDVELFNGVLDQTKCAEFLGTLTPADAIDEAFICGPAPMMDAAEAALKAAGV
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEECCCCHHHHHHHHHHHCCC
PQAKVHVERFGTPLPQAGAPVVEITDQTPAADLEIVLDGKKRKLRLPYEGVSLLDVGLRA
CHHEEEHHHCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHC
GLALPYACKGGVCCTCRAKVLEGEVRMEKNYTLEEHEVKDGFVLTCQCHPISDKVVVSYD
CCCCCCCCCCCEEEEEEHEECCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEC
ER
CC
>Mature Secondary Structure 
ATPQFHPLRIRDVRPETADAVTVSFDVPPELRDAYRFTQGQFVTLKTHIDGEETRRSYS
CCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEEEEECCCHHHCCEEE
ICVGTTDYDRDGELRIGIKRVRGGRFSNFAFDSLQPGHTIDVMTPDGRFFTHLNADHGKQ
EEEECCCCCCCCCEEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCEEEEECCCCCCE
YVAFSGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDAIMFAEELEDLKNRYMNRFVL
EEEEECCCCCHHHHHHHHHHEEECCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHEEE
YHVLSDDQQDVELFNGVLDQTKCAEFLGTLTPADAIDEAFICGPAPMMDAAEAALKAAGV
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEECCCCHHHHHHHHHHHCCC
PQAKVHVERFGTPLPQAGAPVVEITDQTPAADLEIVLDGKKRKLRLPYEGVSLLDVGLRA
CHHEEEHHHCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHC
GLALPYACKGGVCCTCRAKVLEGEVRMEKNYTLEEHEVKDGFVLTCQCHPISDKVVVSYD
CCCCCCCCCCCEEEEEEHEECCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEC
ER
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]