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The map label for this gene is flhA

Identifier: 78064848

GI number: 78064848

Start: 228252

End: 230351

Strand: Direct

Name: flhA

Synonym: Bcep18194_A3371

Alternate gene names: 78064848

Gene position: 228252-230351 (Clockwise)

Preceding gene: 78064847

Following gene: 78064849

Centisome position: 6.18

GC content: 67.29

Gene sequence:

>2100_bases
ATGAGCACCCCGACCGGCCTGTTCGCGAAGCGCCCGAACGTGCTCGCGGGTACCAACCTGCGCGCGCTCGCGGGCCCGAT
CCTCATCTGCATGATTTTGGGGATGATGATCCTGCCGCTGCCGCCGATGCTGCTGGATCTGCTGTTCACGTTCAACATCG
CGCTGTCCGTGATGGTGCTGCTCGTCAGCATGTACACGATGAAGCCGCTCGACTTCGCGGCGTTCCCGAGCGTGCTGCTG
TTCTCCACACTGTTGCGCCTGTCGCTGAACGTCGCGTCGACGCGCGTCGTGCTGCTCGAAGGCCACACGGGCCCGGACGC
GGCCGGCCAGGTGATCGAGGCGTTCGGCCACTTCCTCGTCGGCGGCAACTTCGCGGTCGGCATCGTCGTGTTCGTGATCC
TGATGATCATCAACTTCATGGTGATCACGAAGGGCGCGGGGCGGATCGCCGAAGTGTCCGCGCGCTTCACGCTCGACGCG
ATGCCCGGCAAGCAGATGGCGATCGACGCTGATCTGAACGCGGGCCTCATCAACGAAGAGCAGGCCCGCAAGCGCCGCCT
GGCCGTGTCGCAGGAAGCCGAGTTCTACGGGTCGATGGACGGCGCGTCGAAGTTCGTGCGCGGCGACGCGATCGCCGGCC
TGATCATCATGGCGATCAACGTGATCGGCGGGCTGATCGTCGGGATGGTCCAGCACGACATGAGTTTCGCCGCGGCCGGC
ACGAACTACACGCTGCTGACGATCGGCGACGGCCTCGTCGCGCAGATCCCGTCGCTCGTGATCTCGACCGCGGCCGGCGT
GATCGTGTCGCGCGTCGCGACCGACGAGGACATCGGCACGCAGATCACCGGCCAGCTGTTCACGAACCCGCGCGTGCTGA
ACATCACCGGCGCGATCATCGTGCTGATGGGCCTGATCCCCGGCATGCCGCACTTCGCGTTCCTCGCACTCGGCGGCGGC
GCGATCTGGCTGGCCCGCACGCAGACCAAGCGCGCGGCGGCCCGCAAGGCGGCCGGCGACCTGACCGACATCGCACCGCC
CGCGGTGCTGCCGTCGGACAGCCACGAGGCGACCTGGGACGACGTGCAACTGATCGACCCGCTCGGCCTCGAAGTCGGCT
ACCGGCTGATTCCGCTCGTCGACAAGAACAGCGACGGCGAACTGCTCAAGCGGATCAAGAGCATCCGCAAGAAATTCGCG
CAGGAAATCGGCTTCCTGCCGCCGGTGATCCATATCCGCGACAACCTCGAACTGCGGCCGAACGCTTACCGGATCGCGCT
GAAGGGTGTCGAGATCGGCGTCGGCGAAGTGTTCCCGGGCCAGTGGCTCGCGATCAACCCCGGCCAGGTGACGGCCGCGC
TGCCGGGCGCCGTCACGCAGGATCCCGCGTTCGGGCTGCCGGCCGTGTGGATCGACGTCGCGATGCGCGAACAGGCGCAG
GTGTACGGCTACACGGTGGTCGACGCGAGCACGGTCGTCGCGACGCACCTGAACCATCTGGTCGTCCAGCACGCGGCCGA
GCTGCTCGGCCGCCAGGAAGTGCAGTCGCTCGTCGAGCGCACCGGCAAGGACGCGCCGTCGCTCGTCGAGGACCTCGTGC
CGAAGACGATCTCGCTGACGACGCTGCAGAAGGTGCTGCAGAACCTGCTCGAGGAAGGCGTGCCGATCCGCGACATGCGC
ACGATCCTCGAGGCCGTGTCCGAACACGCGGGCCGCGGCGACGCGTTCGAGATCACGGCCGCGGTGCGGCTGTCGCTCGG
CCGCGCGATCACGCAGCAGTGGTATCCGGGCGCCGGCGAAATGCAGGTGATGGGCCTCGACTCGAATCTGGAGCGCGTGC
TGTCGCAGGCGCTCGCCACCGGCGCGAACCCGGGCCTCGAACCCGGCCTCGCGCACAACCTTCTGACCGGCACGCAACAG
GCGATGCTGCGTCAACAGAATCTCGGGCTGCCGCCCGTGCTGCTGGTGCAGCACGCGCTGCGCGCGATGCTCGCGCGTTT
CCTGCGCCGCAGCCTGCCGCAATTGAAAGTGCTGTCGTATGCCGAAGTGCCGGACACACGCACGATCAAAGTCGTTAACG
TCATCGGGGGTTCCGCTTGA

Upstream 100 bases:

>100_bases
TCGATCTGGAAGTGCCGGCCGACCTCGACAAGGGCTCGTCGGTGTCCGCCGAAGACGAACGCGAAGAGCAGGACGACACG
CTCGGTAAGGGAGGTGTGGC

Downstream 100 bases:

>100_bases
ACATTCGCAAATTCACCGGCGCAACGAGCCGCGACGCACTTCGTCTCGTGCGCGAGGCACTCGGCGCCGACGCGGTCGTG
CTGTCGAACCGCACGCTCGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MSTPTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLL
FSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDA
MPGKQMAIDADLNAGLINEEQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAAG
TNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAIIVLMGLIPGMPHFAFLALGGG
AIWLARTQTKRAAARKAAGDLTDIAPPAVLPSDSHEATWDDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFA
QEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGVGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVAMREQAQ
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQSLVERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLEEGVPIRDMR
TILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGAGEMQVMGLDSNLERVLSQALATGANPGLEPGLAHNLLTGTQQ
AMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA

Sequences:

>Translated_699_residues
MSTPTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLL
FSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDA
MPGKQMAIDADLNAGLINEEQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAAG
TNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAIIVLMGLIPGMPHFAFLALGGG
AIWLARTQTKRAAARKAAGDLTDIAPPAVLPSDSHEATWDDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFA
QEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGVGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVAMREQAQ
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQSLVERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLEEGVPIRDMR
TILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGAGEMQVMGLDSNLERVLSQALATGANPGLEPGLAHNLLTGTQQ
AMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
>Mature_698_residues
STPTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLLF
STLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAM
PGKQMAIDADLNAGLINEEQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAAGT
NYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAIIVLMGLIPGMPHFAFLALGGGA
IWLARTQTKRAAARKAAGDLTDIAPPAVLPSDSHEATWDDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFAQ
EIGFLPPVIHIRDNLELRPNAYRIALKGVEIGVGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVAMREQAQV
YGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQSLVERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLEEGVPIRDMRT
ILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGAGEMQVMGLDSNLERVLSQALATGANPGLEPGLAHNLLTGTQQA
MLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=696, Percent_Identity=65.0862068965517, Blast_Score=885, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74686; Mature: 74555

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVL
CCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
GGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINEE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEEEEECCCCCCEEEECCCCCCCCCHH
QARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAAG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
TNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAII
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHEECCCEEEEHHHHHH
VLMGLIPGMPHFAFLALGGGAIWLARTQTKRAAARKAAGDLTDIAPPAVLPSDSHEATWD
HHHHHHCCCCHHHHHEECCCEEEEEECHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCC
DVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELRP
CHHEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECC
NAYRIALKGVEIGVGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVAMREQAQ
CEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQSLVERTGKDAPSLVEDLVPKTISLT
HEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
TLQKVLQNLLEEGVPIRDMRTILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGAGE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCC
MQVMGLDSNLERVLSQALATGANPGLEPGLAHNLLTGTQQAMLRQQNLGLPPVLLVQHAL
EEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
HHHHHHHHHHCCCCEEHHEECCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
STPTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVL
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
GGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINEE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEEEEECCCCCCEEEECCCCCCCCCHH
QARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAAG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
TNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAII
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHEECCCEEEEHHHHHH
VLMGLIPGMPHFAFLALGGGAIWLARTQTKRAAARKAAGDLTDIAPPAVLPSDSHEATWD
HHHHHHCCCCHHHHHEECCCEEEEEECHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCC
DVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELRP
CHHEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECC
NAYRIALKGVEIGVGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVAMREQAQ
CEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQSLVERTGKDAPSLVEDLVPKTISLT
HEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
TLQKVLQNLLEEGVPIRDMRTILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGAGE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCC
MQVMGLDSNLERVLSQALATGANPGLEPGLAHNLLTGTQQAMLRQQNLGLPPVLLVQHAL
EEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
HHHHHHHHHHCCCCEEHHEECCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]