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The map label for this gene is cheA [H]

Identifier: 78064835

GI number: 78064835

Start: 214200

End: 216449

Strand: Direct

Name: cheA [H]

Synonym: Bcep18194_A3358

Alternate gene names: 78064835

Gene position: 214200-216449 (Clockwise)

Preceding gene: 78064834

Following gene: 78064836

Centisome position: 5.8

GC content: 69.24

Gene sequence:

>2250_bases
ATGACTCTCGACATCACTCAGTTCTACCAGACATTTTTCGACGAAGCGGACGAGCTGCTCGCGCAGATGGAGCAGTTGCT
GCTGAACCTCGACGTCGGCTCGCCCGACCCCGAGGATCTGGCCGCGATCTTCCGCGCCGCGCATTCGATCAAGGGCGGCG
CGGCGACGTTCGGCTTTTCCGCGCTGACCGATACGACGCACATCCTCGAATCGCTGCTCGACCGCGCGCGCAACCATGAG
CTGACGCTGACCAAGGAAATGGTCGACGCTTTCCTGGAGACGAAGGACGTGCTGTCCGACCAGCTCGTCGACTACCGTGC
AAGCGCCGAACCGGACGCGGCCGCTGCCGCGACGATCTGCGCGAAGCTCGAACGGCTGAAGGCCGAGAGCGGCGCGGGTG
CGCCGGCTGCGGCAGCGCCCGTGGCGCCGGTCGTTGCCGCCGTTGCGCCGGCTGCGCCGGCCGTGGAACCGGCCGCCGGC
GATGACCGCGCGCCCGACCACGTGATCGAGCAGGCCGTCGCGGCCGCGCATCCGGCGGGCGACGCCGATGCAGGCGAAGG
CGGCCCGCACCTGAAGATCACGCTCGTGGGCGTCGACGCGAAGGATCGCGAGCTGCTCACCGAAGAACTCGGCAACCTCG
GCCGGATCGTGGCCCGCGAGGAAGCGGGCGGCGACCTGACGCTGTGGGTCGAATCGGACGTGCCGTCCGACGACATCGTC
GCCGTGTGCTGCTTCGTGATCGACGAAAGCCAGATCCGCGTCGGGCACGGCACGGCGCCGGCCGCACCGGCTGCCGCGCA
GGACGCCGCGGCACCGGCAGCCGAACCGGCCGCCGCCGCGCAACCGGTGCGCGCCGAGGTATTCGCGCCGCAGGCCGCGG
CACCGCAGCCGGCCGCATCGGCACCGGCGGCGCCCGCCGAGCCGGCCGCCGCTGCGCCCCAAGCGCAGCAGCCGGCCCAG
CCGGCGCACGCCGACCACGCGCCGCAGGCCGCCGCGCATCACGACGACAAGCGCGCCCGCCCGGCGGCCGCGGCCGCATC
GGGCGCCGAAGGCAGCTCGATCCGCGTCGGCGTCGAGAAGGTCGACCAGTTGATCAACCTGGTCGGCGAACTCGTGATCA
CGCAGGCGATGCTCGCGGAAACCGCGAGCGCGTTCGATCCGGCGCTGCACGACCGCCTGTTCAACGGGATGGCGCAGCTC
GAGCGCAACGCGCGTGACCTGCAGGAAGCCGTGATGTCGATCCGCATGATGCCGATGGACTACGTGTTCAGCCGCTTCCC
GCGTCTCGTGCGCGACCTCGCCGGCAAGCTCGGCAAGCAGGTCGAACTCGTCACGTTCGGCCAGGCGACCGAGCTCGACA
AGAGCCTGATCGAACGGATCATCGATCCGCTGACCCACCTCGTGCGCAACAGCCTCGACCACGGGATCGAGACGGTCGAC
AAGCGCGTCGCCGCCGGCAAGGACGCGGTCGGCCAGCTCGTGCTGTCGGCCGCGCATCACGGCGGCAACATCGTGATCGA
GGTGAGCGACGACGGCGCGGGCCTGAACCGCGAACGCATTCTCGCGAAGGCCGCGAAACAGGGCATGCAGGTGTCCGACA
ACATCAGCGACGACGAAGTCTGGCAGCTGATCTTCGCGCCGGGCTTCTCGACCGCCGAGACGGTGACCGACGTGTCGGGC
CGTGGCGTCGGGATGGACGTCGTGAAGCGCAACATCCAGTCGATGGGCGGCCACGTCGAGATCACGTCGGTGGCCGGCCG
CGGCACGACCACGCGGATCGTGCTGCCGCTCACGCTCGCGATTCTCGACGGGATGTCGGTGAAGGTCGGCAACGAGATCT
TCATCCTGCCGCTGAACTTCGTGATGGAGTCGCTGCAGCCGTCGAACGACGACATCTACACGGTCGGCAACGGCGAACGC
GTGGTGCGCGTGCGCGGCGAATACCTGCCGCTCGTCGCGCTGCACGAGGTGTTCTCGGTCGACGATGCGCGTACCGACCC
GACGCAAGGGATCGTCACGATCATGGAAACCGAGGGACGCCGCTTCGCGATGCTGATCGACGAACTGGTCGGCCAGCAGC
AGGTGGTCGTGAAGAACCTCGAAACCAATTACCGCAAGGTGCACGGCATCTCGGCGGCGACCATCCTCGGCGACGGCAGC
GTCGCGTTGATCGTCGACGTCGCGGCGCTGAACCGCGAAACCCGTGCGATGCACGGCGCCCGTGCCGGCGCCGAGCTCGC
GATGTTCTGA

Upstream 100 bases:

>100_bases
GAAGCCGATCGATCCCGCCGTGCTGGTCGACCTGGTCGCGACGCTGTCCGAACCGGCCGCCTCCTGACATTCACGCGACG
CATTCAACCCGGGACCGGGC

Downstream 100 bases:

>100_bases
TGTCTCTCGCCATTCAACCGCTTGGGGGCCAACGTGGCTGCTGAAGTCCAAATGATCAATCCGGCCGCGGCGAACGCGGC
AACGAGCCGTCGCGACACGG

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 748

Protein sequence:

>749_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGSPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHE
LTLTKEMVDAFLETKDVLSDQLVDYRASAEPDAAAAATICAKLERLKAESGAGAPAAAAPVAPVVAAVAPAAPAVEPAAG
DDRAPDHVIEQAVAAAHPAGDADAGEGGPHLKITLVGVDAKDRELLTEELGNLGRIVAREEAGGDLTLWVESDVPSDDIV
AVCCFVIDESQIRVGHGTAPAAPAAAQDAAAPAAEPAAAAQPVRAEVFAPQAAAPQPAASAPAAPAEPAAAAPQAQQPAQ
PAHADHAPQAAAHHDDKRARPAAAAASGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQL
ERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVD
KRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQVSDNISDDEVWQLIFAPGFSTAETVTDVSG
RGVGMDVVKRNIQSMGGHVEITSVAGRGTTTRIVLPLTLAILDGMSVKVGNEIFILPLNFVMESLQPSNDDIYTVGNGER
VVRVRGEYLPLVALHEVFSVDDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAATILGDGS
VALIVDVAALNRETRAMHGARAGAELAMF

Sequences:

>Translated_749_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGSPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHE
LTLTKEMVDAFLETKDVLSDQLVDYRASAEPDAAAAATICAKLERLKAESGAGAPAAAAPVAPVVAAVAPAAPAVEPAAG
DDRAPDHVIEQAVAAAHPAGDADAGEGGPHLKITLVGVDAKDRELLTEELGNLGRIVAREEAGGDLTLWVESDVPSDDIV
AVCCFVIDESQIRVGHGTAPAAPAAAQDAAAPAAEPAAAAQPVRAEVFAPQAAAPQPAASAPAAPAEPAAAAPQAQQPAQ
PAHADHAPQAAAHHDDKRARPAAAAASGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQL
ERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVD
KRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQVSDNISDDEVWQLIFAPGFSTAETVTDVSG
RGVGMDVVKRNIQSMGGHVEITSVAGRGTTTRIVLPLTLAILDGMSVKVGNEIFILPLNFVMESLQPSNDDIYTVGNGER
VVRVRGEYLPLVALHEVFSVDDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAATILGDGS
VALIVDVAALNRETRAMHGARAGAELAMF
>Mature_748_residues
TLDITQFYQTFFDEADELLAQMEQLLLNLDVGSPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHEL
TLTKEMVDAFLETKDVLSDQLVDYRASAEPDAAAAATICAKLERLKAESGAGAPAAAAPVAPVVAAVAPAAPAVEPAAGD
DRAPDHVIEQAVAAAHPAGDADAGEGGPHLKITLVGVDAKDRELLTEELGNLGRIVAREEAGGDLTLWVESDVPSDDIVA
VCCFVIDESQIRVGHGTAPAAPAAAQDAAAPAAEPAAAAQPVRAEVFAPQAAAPQPAASAPAAPAEPAAAAPQAQQPAQP
AHADHAPQAAAHHDDKRARPAAAAASGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQLE
RNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVDK
RVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQVSDNISDDEVWQLIFAPGFSTAETVTDVSGR
GVGMDVVKRNIQSMGGHVEITSVAGRGTTTRIVLPLTLAILDGMSVKVGNEIFILPLNFVMESLQPSNDDIYTVGNGERV
VRVRGEYLPLVALHEVFSVDDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAATILGDGSV
ALIVDVAALNRETRAMHGARAGAELAMF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=743, Percent_Identity=55.0471063257066, Blast_Score=749, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78775; Mature: 78644

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGSPDPEDLAAIFRAAHSIKGGAATFGFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
ALTDTTHILESLLDRARNHELTLTKEMVDAFLETKDVLSDQLVDYRASAEPDAAAAATIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AKLERLKAESGAGAPAAAAPVAPVVAAVAPAAPAVEPAAGDDRAPDHVIEQAVAAAHPAG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
DADAGEGGPHLKITLVGVDAKDRELLTEELGNLGRIVAREEAGGDLTLWVESDVPSDDIV
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCHHHEEECCCCCCEEEEEEECCCCCHHHH
AVCCFVIDESQIRVGHGTAPAAPAAAQDAAAPAAEPAAAAQPVRAEVFAPQAAAPQPAAS
HHHHHHCCCCCEEECCCCCCCCCCCHHHCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCC
APAAPAEPAAAAPQAQQPAQPAHADHAPQAAAHHDDKRARPAAAAASGAEGSSIRVGVEK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHCCCCCCCEEEECHHH
VDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQLERNARDLQEAVMSIRMMPMD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVD
HHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQVSDNISDDEV
HHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
WQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEITSVAGRGTTTRIVLPLTLA
EEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHH
ILDGMSVKVGNEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEYLPLVALHEVFSV
HHCCCEEEECCEEEEEEHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHC
DDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAATILGDGS
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCC
VALIVDVAALNRETRAMHGARAGAELAMF
EEEEEEHHHHCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TLDITQFYQTFFDEADELLAQMEQLLLNLDVGSPDPEDLAAIFRAAHSIKGGAATFGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
ALTDTTHILESLLDRARNHELTLTKEMVDAFLETKDVLSDQLVDYRASAEPDAAAAATIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AKLERLKAESGAGAPAAAAPVAPVVAAVAPAAPAVEPAAGDDRAPDHVIEQAVAAAHPAG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
DADAGEGGPHLKITLVGVDAKDRELLTEELGNLGRIVAREEAGGDLTLWVESDVPSDDIV
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCHHHEEECCCCCCEEEEEEECCCCCHHHH
AVCCFVIDESQIRVGHGTAPAAPAAAQDAAAPAAEPAAAAQPVRAEVFAPQAAAPQPAAS
HHHHHHCCCCCEEECCCCCCCCCCCHHHCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCC
APAAPAEPAAAAPQAQQPAQPAHADHAPQAAAHHDDKRARPAAAAASGAEGSSIRVGVEK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHCCCCCCCEEEECHHH
VDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQLERNARDLQEAVMSIRMMPMD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVD
HHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQVSDNISDDEV
HHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
WQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEITSVAGRGTTTRIVLPLTLA
EEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHH
ILDGMSVKVGNEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEYLPLVALHEVFSV
HHCCCEEEECCEEEEEEHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHC
DDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAATILGDGS
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCC
VALIVDVAALNRETRAMHGARAGAELAMF
EEEEEEHHHHCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]