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The map label for this gene is atpA1 [H]

Identifier: 78064763

GI number: 78064763

Start: 118608

End: 120149

Strand: Direct

Name: atpA1 [H]

Synonym: Bcep18194_A3286

Alternate gene names: 78064763

Gene position: 118608-120149 (Clockwise)

Preceding gene: 78064762

Following gene: 78064764

Centisome position: 3.21

GC content: 62.26

Gene sequence:

>1542_bases
ATGCAACTCAATCCCTCTGAGATCAGCGAGCTGATCAAGAGCCGGATCCAGGGCCTTGAAGCGAGCGCAGACGTTCGCAA
CCAGGGCACCGTGATCTCCGTGACCGACGGTATCGTGCGTATCCACGGCCTGTCGGACGTGATGCAGGGCGAAATGCTCG
AGTTTCCGGGCAACACGTTCGGTCTCGCGCTGAACCTCGAGCGCGACTCGGTCGGCGCGGTGATTCTCGGCGAATACGAA
CACATCTCGGAAGGCGACATCGTCAAGACGACGGGCCGCATTCTCGAAGTCCCGGTTGGTCCGGAACTCGTCGGCCGTGT
GGTCGATGCGCTCGGCAACCCGATCGACGGCAAGGGCCCGGTCAACGCCAAGCTGACCGATGCGATCGAAAAGATCGCCC
CGGGCGTGATCTGGCGTAAGTCGGTGTCGCAGCCGGTGCAGACGGGCATCAAGTCGATCGACGCAATGGTGCCGATCGGC
CGTGGCCAGCGTGAGCTGATCATCGGCGACCGTCAGTGCGGCAAGACCGCAGTGGCGCTCGACGCGATCATCAACCAGAA
GGGCAAGGACCTGATCTGTATCTACGTCGCGATCGGCCAGAAGGCTTCGTCGATCATGAACGTGGTTCGCAAGCTCGAAG
AAACGGGCGCGATGGAATACACGATCGTCGTCGCCGCTTCGGCTTCGGATTCGGCAGCGATGCAGTACCTCGCACCGTAC
GCCGGCTGCACGATGGGCGAATACTTCCGCGACCGTGGCCAAGACGCGCTGATCATTTATGACGACTTGACCAAGCAAGC
CTGGGCATACCGTCAGATCTCGCTGCTGCTGCGCCGCCCGCCGGGCCGTGAAGCGTACCCGGGTGACGTGTTCTATCTCC
ACTCGCGTCTGCTCGAGCGTGCTGCTCGCGTCTCGGAAGAGTACGTCGAGAAGTTCACGAACGGCGAAGTGAAGGGCAAG
AGCGGTTCGCTGACGGCACTGCCGGTCATCGAAACGCAGGCTGGCGACGTGACCGCGTTCGTTCCGACGAACGTGATCTC
GATTACCGACGGCCAGATCTTCCTGGAAACCGACCTGTTCAACGCAGGCATCCGCCCGGCAATCAACGCCGGCGTGTCGG
TGTCGCGAGTCGGTGGCGCCGCTCAGACGAAGGTCGTGAAGAAGCTGTCGGGCGGTATCCGTACCGACCTCGCGCAGTAC
CGTGAACTGGCGGCATTCGCCCAGTTCGCATCGGACCTCGACGAAGCGACCCGCAAGCAGCTCGAGCGCGGCCGCCGCGT
GACGGAACTGCTGAAGCAGCCGCAGTACCAGCCGCTGCAGGTGTGGGAACTGGCCGTGTCGCTGTACGCCGCGAACAACG
GCTACCTCGACGACCTCGACGTCAAGCAAGTGCTGTCGTTCGAGAAGGGCCTGCGCGAAAGCCTGAAGACCAGCAACGCT
GACCTCATCAAGCGCATCGAAGACACCAAGGATCTCTCGAAGGACGACGAAGGCGCACTGCGCTCGGCGATCGAATCCTT
CAAGAAGTCCGGTGCCTATTGA

Upstream 100 bases:

>100_bases
TCGACACCTCGGTTCGCGCGCGCCTCGCATCGATGCAGGCAGCGTTGACCGCCTGAGCGCCACGCCGGCACGCAACAGAA
TTGACTATCAGGAGCGAATA

Downstream 100 bases:

>100_bases
TCCGCGAGTGACACACTGAGGCCGCGCGGGTGCTGATGCGCCCGCGCCGCTTCGGTCAAGGAGCAAGCTATGGCTGGAAT
GAAGGAAATTCGCGGCAAGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1 [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYE
HISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIG
RGQRELIIGDRQCGKTAVALDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMEYTIVVAASASDSAAMQYLAPY
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLYAANNGYLDDLDVKQVLSFEKGLRESLKTSNA
DLIKRIEDTKDLSKDDEGALRSAIESFKKSGAY

Sequences:

>Translated_513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYE
HISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIG
RGQRELIIGDRQCGKTAVALDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMEYTIVVAASASDSAAMQYLAPY
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLYAANNGYLDDLDVKQVLSFEKGLRESLKTSNA
DLIKRIEDTKDLSKDDEGALRSAIESFKKSGAY
>Mature_513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYE
HISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIG
RGQRELIIGDRQCGKTAVALDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMEYTIVVAASASDSAAMQYLAPY
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLYAANNGYLDDLDVKQVLSFEKGLRESLKTSNA
DLIKRIEDTKDLSKDDEGALRSAIESFKKSGAY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=57.0588235294118, Blast_Score=588, Evalue=1e-168,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=57.0588235294118, Blast_Score=588, Evalue=1e-168,
Organism=Homo sapiens, GI19913428, Length=308, Percent_Identity=28.2467532467532, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI32189394, Length=436, Percent_Identity=24.3119266055046, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI19913426, Length=314, Percent_Identity=27.3885350318471, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913424, Length=319, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=68.8109161793372, Blast_Score=731, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=29.8932384341637, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790170, Length=377, Percent_Identity=24.4031830238727, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=56.6666666666667, Blast_Score=582, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=56.6666666666667, Blast_Score=581, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=52.3529411764706, Blast_Score=526, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI17570191, Length=314, Percent_Identity=28.0254777070064, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=382, Percent_Identity=25.3926701570681, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=435, Percent_Identity=24.367816091954, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=249, Percent_Identity=28.9156626506024, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=39.7260273972603, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=55.9686888454012, Blast_Score=580, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6322581, Length=426, Percent_Identity=25.8215962441315, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=382, Percent_Identity=27.2251308900524, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=57.2549019607843, Blast_Score=587, Evalue=1e-168,
Organism=Drosophila melanogaster, GI281361666, Length=316, Percent_Identity=27.2151898734177, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=316, Percent_Identity=27.2151898734177, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=316, Percent_Identity=27.2151898734177, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638766, Length=396, Percent_Identity=24.4949494949495, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574560, Length=395, Percent_Identity=23.7974683544304, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583992, Length=319, Percent_Identity=26.9592476489028, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583988, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583986, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583984, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129479, Length=250, Percent_Identity=28.8, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55752; Mature: 55752

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECHHHHHCCCCEECCCCEE
GLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIGRGQRELIIGDRQCGKTAVAL
CCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMEYTIVVAASASDSAAMQYLAPY
HHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECHH
NAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWELAVSLYAANNGYLDDLDVKQVLSFEKGLRESLKTSNA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCH
DLIKRIEDTKDLSKDDEGALRSAIESFKKSGAY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECHHHHHCCCCEECCCCEE
GLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIGRGQRELIIGDRQCGKTAVAL
CCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMEYTIVVAASASDSAAMQYLAPY
HHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECHH
NAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWELAVSLYAANNGYLDDLDVKQVLSFEKGLRESLKTSNA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCH
DLIKRIEDTKDLSKDDEGALRSAIESFKKSGAY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA