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The map label for this gene is namA [H]

Identifier: 78064730

GI number: 78064730

Start: 87255

End: 88367

Strand: Direct

Name: namA [H]

Synonym: Bcep18194_A3253

Alternate gene names: 78064730

Gene position: 87255-88367 (Clockwise)

Preceding gene: 78064729

Following gene: 78064731

Centisome position: 2.36

GC content: 69.81

Gene sequence:

>1113_bases
ATGACTGCGCTGTTTTCCCCGTTCACGCTGCGCGGCGTGACCCTTCCGAACCGGATCGTGATCTCCCCGATGTGCCAGTA
TTCGGCCGAACGCGGCGAGGCGACCGACTGGCACATGATTCACCTCGGCCATCTCGCGCTGTCGGGCGCGGGGCTGCTCT
GCATCGAGGCGACCGCCGTGGAACCCGACGGGCGTATCACGCATGGCGACCTCGGCCTCTGGGACGACGTGACCGAAGCC
GCGCTGAAGCCGGTGCTGGCCGCGATCCGCAAGCATTCGCCGGTCCGCGTCGCGATGCAGTTGTCGCATGCGGGGCGCAA
GGCGTCGAGCAACGTGCCGTGGCAGGGTGGTCAGCTCGTATCGGTCGCCGACGGCGGCTGGTTGCCGCATGCGCCGTCGG
CCGTGCCGCACAAGGACGGCGAGACGCCGCCGCTCGCACTCGATGCCGCGGGCCTGAACCGGATCCGCGAAGCGTTCGCG
GCCTCGGCGAAGCGGGCCGCACGGCTCGGCATCGACGCGATCGAGGTGCATGCGGCACACGGCTACCTGCTGCACCAGTT
CCTGTCGCCGCTCGCGAACCAGCGCACCGACGAATACGGCGGCTCGCTCGAAAACCGCATGCGTTTCCCGCTCGAGATCT
TCGAGATCGTGCGCGCGGCGTTTCCGGAAGGCCGGCCGGTCGGCGTGCGCGTGTCCGCGACCGACTGGGTCGAAGGCGGC
TGGGAGCTCGACGATACGATCGCGTTCGCGCACGAACTGAAGCGCCGCGGCTGCGACTGGATCGACGTGTCGTCCGGCGG
CGTGTCGCCGCTGCAGAAGATTCCGCTGTCGGCCGGCTACCAGGTGCCGTTCGCGCAGGCCGTGAAGCGCGCGGTCGGCA
TGCCGACGATCGCCGTCGGCCTGATCAACGAGCCCGCGCATGCGAACCGACTCATCGAGGCCGGCGATGCCGACTTCGTC
GCGATGGCGCGTGCGATGCTGTACGACCCGCGCTGGCCGTGGCATGCGGCGGCCGAGCTCGGCGCGCAGGTGACGGCGCC
GCCGCAATACTGGCGCTCGCAGCCGCGCGAGCACAAGGCGTTGTTCGGCGACATCGCATTCGGCCAGCGTTGA

Upstream 100 bases:

>100_bases
CCGTACCTGACCATCCGCTTACTGCCGGGTGCGCCATCTGCACGCTCGCCGCCTGCGTGCTACGCTCGTTCGCTCTTTCC
TTTCCTGGCGAGCGGCCTCC

Downstream 100 bases:

>100_bases
GCACCGCGCGCGCAATATTGCGCGTGATGTTGAACGAAGCAATCGTGAACGTGTAGGATGCGGGTGATTCGCCGCATGCC
CCGACGCGGCACCGACCGGT

Product: NADH-flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAVEPDGRITHGDLGLWDDVTEA
ALKPVLAAIRKHSPVRVAMQLSHAGRKASSNVPWQGGQLVSVADGGWLPHAPSAVPHKDGETPPLALDAAGLNRIREAFA
ASAKRAARLGIDAIEVHAAHGYLLHQFLSPLANQRTDEYGGSLENRMRFPLEIFEIVRAAFPEGRPVGVRVSATDWVEGG
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSAGYQVPFAQAVKRAVGMPTIAVGLINEPAHANRLIEAGDADFV
AMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKALFGDIAFGQR

Sequences:

>Translated_370_residues
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAVEPDGRITHGDLGLWDDVTEA
ALKPVLAAIRKHSPVRVAMQLSHAGRKASSNVPWQGGQLVSVADGGWLPHAPSAVPHKDGETPPLALDAAGLNRIREAFA
ASAKRAARLGIDAIEVHAAHGYLLHQFLSPLANQRTDEYGGSLENRMRFPLEIFEIVRAAFPEGRPVGVRVSATDWVEGG
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSAGYQVPFAQAVKRAVGMPTIAVGLINEPAHANRLIEAGDADFV
AMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKALFGDIAFGQR
>Mature_369_residues
TALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAVEPDGRITHGDLGLWDDVTEAA
LKPVLAAIRKHSPVRVAMQLSHAGRKASSNVPWQGGQLVSVADGGWLPHAPSAVPHKDGETPPLALDAAGLNRIREAFAA
SAKRAARLGIDAIEVHAAHGYLLHQFLSPLANQRTDEYGGSLENRMRFPLEIFEIVRAAFPEGRPVGVRVSATDWVEGGW
ELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSAGYQVPFAQAVKRAVGMPTIAVGLINEPAHANRLIEAGDADFVA
MARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKALFGDIAFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=332, Percent_Identity=27.1084337349398, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1787939, Length=351, Percent_Identity=29.9145299145299, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=266, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=178, Percent_Identity=34.8314606741573, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=197, Percent_Identity=31.9796954314721, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=203, Percent_Identity=31.5270935960591, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17559804, Length=199, Percent_Identity=33.6683417085427, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17565138, Length=274, Percent_Identity=27.007299270073, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=290, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=236, Percent_Identity=29.6610169491525, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=265, Percent_Identity=29.0566037735849, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40067; Mature: 39936

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAV
CCCCCCCCEEECCCCCCEEEECHHHHHCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
EPDGRITHGDLGLWDDVTEAALKPVLAAIRKHSPVRVAMQLSHAGRKASSNVPWQGGQLV
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCEEE
SVADGGWLPHAPSAVPHKDGETPPLALDAAGLNRIREAFAASAKRAARLGIDAIEVHAAH
EEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
GYLLHQFLSPLANQRTDEYGGSLENRMRFPLEIFEIVRAAFPEGRPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCHHCCCC
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSAGYQVPFAQAVKRAVGMPTIAVG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEE
LINEPAHANRLIEAGDADFVAMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKA
ECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCCCHHHHH
LFGDIAFGQR
HHHHHCCCCC
>Mature Secondary Structure 
TALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAV
CCCCCCCEEECCCCCCEEEECHHHHHCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
EPDGRITHGDLGLWDDVTEAALKPVLAAIRKHSPVRVAMQLSHAGRKASSNVPWQGGQLV
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCEEE
SVADGGWLPHAPSAVPHKDGETPPLALDAAGLNRIREAFAASAKRAARLGIDAIEVHAAH
EEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
GYLLHQFLSPLANQRTDEYGGSLENRMRFPLEIFEIVRAAFPEGRPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCHHCCCC
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSAGYQVPFAQAVKRAVGMPTIAVG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEE
LINEPAHANRLIEAGDADFVAMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKA
ECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCCCHHHHH
LFGDIAFGQR
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA