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The map label for this gene is cidA [H]

Identifier: 78064704

GI number: 78064704

Start: 59302

End: 59778

Strand: Reverse

Name: cidA [H]

Synonym: Bcep18194_A3227

Alternate gene names: 78064704

Gene position: 59778-59302 (Counterclockwise)

Preceding gene: 78064706

Following gene: 78064703

Centisome position: 1.62

GC content: 74.63

Gene sequence:

>477_bases
ATGACCAAGCCGACCGCCGCACTCGCCACTCGCCCCGCCGCTTCGGGCAGCCTCGCGCGCACGGGCCGGATCGCGCTGCA
GGCCGCCGCGCTCGGCGCGCTGTGGATGGCGGTCGACTGGGCCGTGCGCAAGATCGGGCTGCCGATTCCGTCCGGCGTGA
TCGGCCTCGCGGTGCTCCTCGTGCTGCTGTTCTCGGGCCGCGTCGCGCCCGCGTGGGTGAAGGACGGCGCGAACTGGCTG
CTGTCCGACATGCTGCTGTTCTTCGTGCCGGCCGCCGTCGCGGCCGTGCAGTACGGCGGGCTGTTCCGCGAGGACGGCTG
GCGCATCGCGCTGGTGATGCTCGCCGGCACCGCGTTCGTGATGGTCGCAGTGGCCGTCGCGGTCGACCTCGCCGCGAAGC
TCGAGCGCCGGCTCGCCGCGCAGCGCGTGTTCGCCGAACGCCGCCGCACGCGCCTGAGCGCCGCGTCCGCCCACTGA

Upstream 100 bases:

>100_bases
TCCGAATTGGAATGACAAGGATAGAGACAAGTCATTTTATTTATGGTTAGGGGAAACCCTATACTCCCACCATCAACGCA
ATATCTGTAGGGAGCCCGCC

Downstream 100 bases:

>100_bases
GCCGGAGCCTGCCATGTTTGCCGCACTGTCGAACCTGTCCGCCGACCAGGCGAACACCGCGATCTCGTTCGGCTGCTTCG
TGCTGACGGTCGTGCTGTAT

Product: LrgA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTKPTAALATRPAASGSLARTGRIALQAAALGALWMAVDWAVRKIGLPIPSGVIGLAVLLVLLFSGRVAPAWVKDGANWL
LSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFVMVAVAVAVDLAAKLERRLAAQRVFAERRRTRLSAASAH

Sequences:

>Translated_158_residues
MTKPTAALATRPAASGSLARTGRIALQAAALGALWMAVDWAVRKIGLPIPSGVIGLAVLLVLLFSGRVAPAWVKDGANWL
LSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFVMVAVAVAVDLAAKLERRLAAQRVFAERRRTRLSAASAH
>Mature_157_residues
TKPTAALATRPAASGSLARTGRIALQAAALGALWMAVDWAVRKIGLPIPSGVIGLAVLLVLLFSGRVAPAWVKDGANWLL
SDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFVMVAVAVAVDLAAKLERRLAAQRVFAERRRTRLSAASAH

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 16661; Mature: 16530

Theoretical pI: Translated: 12.13; Mature: 12.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPTAALATRPAASGSLARTGRIALQAAALGALWMAVDWAVRKIGLPIPSGVIGLAVLL
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLLFSGRVAPAWVKDGANWLLSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFV
HHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEHHHHHHHHHHH
MVAVAVAVDLAAKLERRLAAQRVFAERRRTRLSAASAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKPTAALATRPAASGSLARTGRIALQAAALGALWMAVDWAVRKIGLPIPSGVIGLAVLL
CCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLLFSGRVAPAWVKDGANWLLSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFV
HHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEHHHHHHHHHHH
MVAVAVAVDLAAKLERRLAAQRVFAERRRTRLSAASAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA