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The map label for this gene is rssA [H]

Identifier: 78064692

GI number: 78064692

Start: 49320

End: 50753

Strand: Reverse

Name: rssA [H]

Synonym: Bcep18194_A3215

Alternate gene names: 78064692

Gene position: 50753-49320 (Counterclockwise)

Preceding gene: 78064693

Following gene: 78064691

Centisome position: 1.37

GC content: 70.08

Gene sequence:

>1434_bases
ATGACACTCCCGACCGCGCCGGCGCTCCCGGCGCGGTTCGGCATTTCGGAGAAGGAGCGCAACAGGATGGCGCACAGCCT
GCGCGGACGGTTGCTGTGGTGGCTGCTGCTGCCGCTCGCGGTGTTCGTGCTGATCGCCGGCGCGATGTCGTACGACACCG
CGCGGACCACGGCCGCGCTCGTGCAGGACAGCGCGCTCGTCGCGTCGGCTCGCACGATCGGCGAGGACATCGAATGGCGC
AACGGGCTGCCGGTCGCCGACGTGCCGCCGGCCGCGCTGGAGATCTTCGAATCGCCGTCGCGCGATTCGGTGTTCTACAA
GGTGATCGACGGCCACGACCGACTGCTCGCAGGCACGCCGGCGCTCGACGTACCCGCGCGGCACGGCATCGAGCCGACGT
TGTACGACACGTCGCTCGACGGCGTGCCGCTGCGCGCGGTGGCCTACGATCGCCAGCTTTACGACGAGGGAAACGTCGAG
ACGGTCACGGTGGTCGTCGCGAAGACGACGCGCTCGCACCAGGCGATGGTCGCCACGATCTGGCGGCCGCAGCTCGTGCG
CCTGTCGCTGATGCTGATGCTCGCGATGGGGCTCGTGTACCTCGGCCTCACCTTCGAGATGCGCCCGCTGATGAAGCTGA
AGGACGACGTGGCCGACCGCGGGCCGATGGAGCTGGAGCCGATCCGCCCCGAGCGGCTGCAGAACGAGCTGCGGCCGATC
GTGGACGCGATCAACCAGTGCATCGCGCGGCTCAACACGCACACGGCCACGCAGCGCCGCTTCATCGCGGATGCCGCGCA
CCAGTTGCGCACGCCGATCGCGGTGCTCGACACGCAGATCCAGTACGCGCAGCGGCGCGGGCACGCCGATCCGGAGCTGG
CAGCGGTGCTCGACAGCATGCAGCGCAGCAGCCGCAAGATGGCCGACGTGACCGACAAGCTGCTGCTGCTCGCGCATGCG
GAAGCGACACCGTCGACGCTGCTGAACCATCGCGTCGATCTCGCGGCCGTGGTGTCGAGTGTGCTGGAGGAAACGATCGT
GCTCGCGCAGCGGCGCAATATCGATCTCGGGGCCGACCTCGGCGAGCGGCTCGACGTCGCGGGCAGCGACAGCCTGCTGA
CCGCGCTGGTGATGAACCTCGTCGACAACGCGGTGCGCTACACGCAGCCGGGCGGCTGCGTGACGGTCTGCGCCCGCCGC
GACGGCGACGCGATCGTGCTCGACGTGGTCGACAACGGCCCCGGCATCCCGGCCGAAGCGCGGCCGCACGTGTTCAAGCG
GTTCTACCGCGTGTCGGCCGATACCGAAGGCTCGGGCCTCGGGCTCGCGATCGTCCGCGAGATCGCGCAGGCGCACGGCG
GCAGCGCGTCGCTCGCGCCGGGGGCCGGCAATCGCGGTATCGTCGTGACCGTGCGGCTGCCCGCATACGATTGA

Upstream 100 bases:

>100_bases
GTGGTCGCGCTGGCCGCCGACTACCTGCTGACGTGGCTCGAGAAGCGGCTGCTGAAGTGGCGCCCCGCGGCGTTCTGAAC
GCCGCAGACGGACGCCTGAC

Downstream 100 bases:

>100_bases
AGAGAAGTCGCCATGAAACTCCTGCTGGTCGAAGACAACGCCGAACTCGCGCACTGGATCGTGAACCTGCTGCGCGGCGA
GGATTTCGCGGTCGACTCCG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MTLPTAPALPARFGISEKERNRMAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDIEWR
NGLPVADVPPAALEIFESPSRDSVFYKVIDGHDRLLAGTPALDVPARHGIEPTLYDTSLDGVPLRAVAYDRQLYDEGNVE
TVTVVVAKTTRSHQAMVATIWRPQLVRLSLMLMLAMGLVYLGLTFEMRPLMKLKDDVADRGPMELEPIRPERLQNELRPI
VDAINQCIARLNTHTATQRRFIADAAHQLRTPIAVLDTQIQYAQRRGHADPELAAVLDSMQRSSRKMADVTDKLLLLAHA
EATPSTLLNHRVDLAAVVSSVLEETIVLAQRRNIDLGADLGERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARR
DGDAIVLDVVDNGPGIPAEARPHVFKRFYRVSADTEGSGLGLAIVREIAQAHGGSASLAPGAGNRGIVVTVRLPAYD

Sequences:

>Translated_477_residues
MTLPTAPALPARFGISEKERNRMAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDIEWR
NGLPVADVPPAALEIFESPSRDSVFYKVIDGHDRLLAGTPALDVPARHGIEPTLYDTSLDGVPLRAVAYDRQLYDEGNVE
TVTVVVAKTTRSHQAMVATIWRPQLVRLSLMLMLAMGLVYLGLTFEMRPLMKLKDDVADRGPMELEPIRPERLQNELRPI
VDAINQCIARLNTHTATQRRFIADAAHQLRTPIAVLDTQIQYAQRRGHADPELAAVLDSMQRSSRKMADVTDKLLLLAHA
EATPSTLLNHRVDLAAVVSSVLEETIVLAQRRNIDLGADLGERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARR
DGDAIVLDVVDNGPGIPAEARPHVFKRFYRVSADTEGSGLGLAIVREIAQAHGGSASLAPGAGNRGIVVTVRLPAYD
>Mature_476_residues
TLPTAPALPARFGISEKERNRMAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDIEWRN
GLPVADVPPAALEIFESPSRDSVFYKVIDGHDRLLAGTPALDVPARHGIEPTLYDTSLDGVPLRAVAYDRQLYDEGNVET
VTVVVAKTTRSHQAMVATIWRPQLVRLSLMLMLAMGLVYLGLTFEMRPLMKLKDDVADRGPMELEPIRPERLQNELRPIV
DAINQCIARLNTHTATQRRFIADAAHQLRTPIAVLDTQIQYAQRRGHADPELAAVLDSMQRSSRKMADVTDKLLLLAHAE
ATPSTLLNHRVDLAAVVSSVLEETIVLAQRRNIDLGADLGERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARRD
GDAIVLDVVDNGPGIPAEARPHVFKRFYRVSADTEGSGLGLAIVREIAQAHGGSASLAPGAGNRGIVVTVRLPAYD

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=320, Percent_Identity=30.625, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=32.0675105485232, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789403, Length=286, Percent_Identity=34.965034965035, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=31.5972222222222, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790861, Length=290, Percent_Identity=27.9310344827586, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787374, Length=297, Percent_Identity=24.5791245791246, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=28.2157676348548, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=238, Percent_Identity=27.7310924369748, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=28.6384976525822, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=247, Percent_Identity=27.1255060728745, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=26.4957264957265, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789808, Length=301, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=26.4069264069264, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=219, Percent_Identity=27.8538812785388, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=29.2792792792793, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081816, Length=263, Percent_Identity=27.7566539923954, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=22.2672064777328, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=27.3148148148148, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51900; Mature: 51769

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPTAPALPARFGISEKERNRMAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAAL
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VQDSALVASARTIGEDIEWRNGLPVADVPPAALEIFESPSRDSVFYKVIDGHDRLLAGTP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEECCC
ALDVPARHGIEPTLYDTSLDGVPLRAVAYDRQLYDEGNVETVTVVVAKTTRSHQAMVATI
CCCCCHHCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHH
WRPQLVRLSLMLMLAMGLVYLGLTFEMRPLMKLKDDVADRGPMELEPIRPERLQNELRPI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VDAINQCIARLNTHTATQRRFIADAAHQLRTPIAVLDTQIQYAQRRGHADPELAAVLDSM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QRSSRKMADVTDKLLLLAHAEATPSTLLNHRVDLAAVVSSVLEETIVLAQRRNIDLGADL
HHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARRDGDAIVLDVVDNGPGIPAEA
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCC
RPHVFKRFYRVSADTEGSGLGLAIVREIAQAHGGSASLAPGAGNRGIVVTVRLPAYD
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TLPTAPALPARFGISEKERNRMAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAAL
CCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VQDSALVASARTIGEDIEWRNGLPVADVPPAALEIFESPSRDSVFYKVIDGHDRLLAGTP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEECCC
ALDVPARHGIEPTLYDTSLDGVPLRAVAYDRQLYDEGNVETVTVVVAKTTRSHQAMVATI
CCCCCHHCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHH
WRPQLVRLSLMLMLAMGLVYLGLTFEMRPLMKLKDDVADRGPMELEPIRPERLQNELRPI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VDAINQCIARLNTHTATQRRFIADAAHQLRTPIAVLDTQIQYAQRRGHADPELAAVLDSM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QRSSRKMADVTDKLLLLAHAEATPSTLLNHRVDLAAVVSSVLEETIVLAQRRNIDLGADL
HHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARRDGDAIVLDVVDNGPGIPAEA
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCC
RPHVFKRFYRVSADTEGSGLGLAIVREIAQAHGGSASLAPGAGNRGIVVTVRLPAYD
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA