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The map label for this gene is srpA [H]

Identifier: 78064673

GI number: 78064673

Start: 28710

End: 29804

Strand: Reverse

Name: srpA [H]

Synonym: Bcep18194_A3196

Alternate gene names: 78064673

Gene position: 29804-28710 (Counterclockwise)

Preceding gene: 78064676

Following gene: 78064672

Centisome position: 0.81

GC content: 69.04

Gene sequence:

>1095_bases
ATGGAGCGATCTTCTTCCTCTTCTTCGCCGCAGCGCGAGCCCGGGCGCGGGTGGTGGCGCTGGGCCGCGATCGGCGGCGC
GGTGGCCGGCGTGGCCGTGGCGTTCGGGTATGTCGGCGGCTGGCTCGCGCCGGCGCGTCTGACCCCGCACCGGATCGTCG
ACGCGTTGCAGACGGCCGGCGGCGGCATTCACCCGGGCTTCCGGCGCAATCACGCGAAGGGCGTGTGCGTGACCGGCTAC
TTCGAAGGCAATGGCGCCGCGAGCATGTATTCGGTCGCGCCGTTCTTCAAGGCGGTGCGTACGCCGGTGGTTGGACGATT
CGCGTTGCCGGGCGGGAATCCGTATGCGCCAGACAGCAGCGTGCCGATTCGCAGCCTCGCGCTGAGGCTCACCGCACCGG
ACGGCGAGCAATGGCGAACCGGGATGAACGCGATGCCGGTGTTTCCGGTCGCGACGCCGCAGGCGTTCTACGCGCAATTG
ATGGCGACCCGGCCCGATCCGAAGACGGGCAAGCCCGATCCGGCCAAGGTGAAGGCGTTTTTCGGATCGCACCCTGAGAC
GGCCGCGTTCCTGCAGTGGATCAAAGGTGCGAAGCCGAGCGCGAGTTACGTCACCGAAAGCTATTACGGATTGAACGCGT
TCTACTTCGTCGATGCGGCCGGCAAGCGCCAGGCGGTGCGGTGGCGCGTCGTGCCGGAGCAGTCGGCCGGCGCCGGTGAC
GTCGCGACGGCGGCGGACCCGAACGTATTGCAGCAGGACGTGACGCAGCGGATCGCGGCCGGTCCGCAGAAGTGGAAGCT
GCTGGTCACGCTGGCGGAGCCCGGCGATCCGGTGGACGACGCGACGAAGGTCTGGCCCGCGCAGCGCACGACGATCGATG
CGGGCACGCTCGTGCTCGACCGCGTGGAGGCGCAGGACAGCGGGCCGTGCCGCGACGTGAATTACGACCCGACGGTGCTG
CCGCAGGGAATTCAGGTATCGGGGGATCCGTTGCTGCCGGCGCGGTCGGCGGCTTACGCGGATTCGTATCTGCGCAGGAC
GAGTGAAGAGGCCGGGGTGGCAGGCGTGGCGCGATTGAGTGGGGAGGGACGGTGA

Upstream 100 bases:

>100_bases
CTTATTCCACCAGCATAGGAAAAAACTTTTCGTGGAATAAACCAGCGCGGGTGGCGTCCTACGCGGGTTCGACAATGACC
TGACGGTCGGGAGCCTATAT

Downstream 100 bases:

>100_bases
TGAAGGCTTCGACGACGTTTAGCTTGCCGGCGCGGGTGCTGCACTGGGTGATGGCCGCGATGATCATCGCGATGCTGTTC
ATCGGGGTGGGGATGGTGGC

Product: catalase-like

Products: O2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MERSSSSSSPQREPGRGWWRWAAIGGAVAGVAVAFGYVGGWLAPARLTPHRIVDALQTAGGGIHPGFRRNHAKGVCVTGY
FEGNGAASMYSVAPFFKAVRTPVVGRFALPGGNPYAPDSSVPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPQAFYAQL
MATRPDPKTGKPDPAKVKAFFGSHPETAAFLQWIKGAKPSASYVTESYYGLNAFYFVDAAGKRQAVRWRVVPEQSAGAGD
VATAADPNVLQQDVTQRIAAGPQKWKLLVTLAEPGDPVDDATKVWPAQRTTIDAGTLVLDRVEAQDSGPCRDVNYDPTVL
PQGIQVSGDPLLPARSAAYADSYLRRTSEEAGVAGVARLSGEGR

Sequences:

>Translated_364_residues
MERSSSSSSPQREPGRGWWRWAAIGGAVAGVAVAFGYVGGWLAPARLTPHRIVDALQTAGGGIHPGFRRNHAKGVCVTGY
FEGNGAASMYSVAPFFKAVRTPVVGRFALPGGNPYAPDSSVPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPQAFYAQL
MATRPDPKTGKPDPAKVKAFFGSHPETAAFLQWIKGAKPSASYVTESYYGLNAFYFVDAAGKRQAVRWRVVPEQSAGAGD
VATAADPNVLQQDVTQRIAAGPQKWKLLVTLAEPGDPVDDATKVWPAQRTTIDAGTLVLDRVEAQDSGPCRDVNYDPTVL
PQGIQVSGDPLLPARSAAYADSYLRRTSEEAGVAGVARLSGEGR
>Mature_364_residues
MERSSSSSSPQREPGRGWWRWAAIGGAVAGVAVAFGYVGGWLAPARLTPHRIVDALQTAGGGIHPGFRRNHAKGVCVTGY
FEGNGAASMYSVAPFFKAVRTPVVGRFALPGGNPYAPDSSVPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPQAFYAQL
MATRPDPKTGKPDPAKVKAFFGSHPETAAFLQWIKGAKPSASYVTESYYGLNAFYFVDAAGKRQAVRWRVVPEQSAGAGD
VATAADPNVLQQDVTQRIAAGPQKWKLLVTLAEPGDPVDDATKVWPAQRTTIDAGTLVLDRVEAQDSGPCRDVNYDPTVL
PQGIQVSGDPLLPARSAAYADSYLRRTSEEAGVAGVARLSGEGR

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=295, Percent_Identity=28.135593220339, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI48994891, Length=296, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71998444, Length=300, Percent_Identity=27, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25147792, Length=295, Percent_Identity=25.4237288135593, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI25151141, Length=295, Percent_Identity=25.4237288135593, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920968, Length=362, Percent_Identity=27.3480662983425, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17981717, Length=293, Percent_Identity=26.6211604095563, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6

Molecular weight: Translated: 38694; Mature: 38694

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSSSSSSPQREPGRGWWRWAAIGGAVAGVAVAFGYVGGWLAPARLTPHRIVDALQTAG
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GGIHPGFRRNHAKGVCVTGYFEGNGAASMYSVAPFFKAVRTPVVGRFALPGGNPYAPDSS
CCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
VPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPQAFYAQLMATRPDPKTGKPDPAKVKAF
CCHHHEEEEEECCCCHHHHCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FGSHPETAAFLQWIKGAKPSASYVTESYYGLNAFYFVDAAGKRQAVRWRVVPEQSAGAGD
HCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCC
VATAADPNVLQQDVTQRIAAGPQKWKLLVTLAEPGDPVDDATKVWPAQRTTIDAGTLVLD
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCEECCCCEEEE
RVEAQDSGPCRDVNYDPTVLPQGIQVSGDPLLPARSAAYADSYLRRTSEEAGVAGVARLS
ECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCHHCCCEEEEECC
GEGR
CCCC
>Mature Secondary Structure
MERSSSSSSPQREPGRGWWRWAAIGGAVAGVAVAFGYVGGWLAPARLTPHRIVDALQTAG
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GGIHPGFRRNHAKGVCVTGYFEGNGAASMYSVAPFFKAVRTPVVGRFALPGGNPYAPDSS
CCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
VPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPQAFYAQLMATRPDPKTGKPDPAKVKAF
CCHHHEEEEEECCCCHHHHCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FGSHPETAAFLQWIKGAKPSASYVTESYYGLNAFYFVDAAGKRQAVRWRVVPEQSAGAGD
HCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCC
VATAADPNVLQQDVTQRIAAGPQKWKLLVTLAEPGDPVDDATKVWPAQRTTIDAGTLVLD
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCEECCCCEEEE
RVEAQDSGPCRDVNYDPTVLPQGIQVSGDPLLPARSAAYADSYLRRTSEEAGVAGVARLS
ECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCHHCCCEEEEECC
GEGR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: H2O2

Specific reaction: 2 H2O2 = O2 + 2 H2O

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]