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The map label for this gene is mas [H]

Identifier: 78049926

GI number: 78049926

Start: 5025776

End: 5026756

Strand: Reverse

Name: mas [H]

Synonym: XCV4370

Alternate gene names: 78049926

Gene position: 5026756-5025776 (Counterclockwise)

Preceding gene: 78049927

Following gene: 78049924

Centisome position: 97.07

GC content: 67.69

Gene sequence:

>981_bases
ATGCGCGCAGCCATCCACACCCGGTTCGGCGACCCGGCCAAGGTGCTCGAACTTGGCGAGCGGCCCACACCGCAACCCGG
CAAGGGCCAGGTCCGCATCGCGATGCGGCGTTCGCCCATCCACAACCATGACCTGTGGACGGTGCGCGGCAACTACGGCT
ACAAGCCCACGTTGCCGGCGATCGGCGGCAGCGAAGGGTCTGGAGTGATCGATGCGCTGGGCGAAGGCGTCCAGGACCTG
CAGGTCGGCCAGCGCGTCGTCGCTGCCGGCGTGCACGAGAGCTGGGCCGACTACTTTCTGGCCGAGGCGACCGGCGTGGT
CCCACTGCCCGATGCACTGGATGACGACCGTGGCTGCCAGCTCATCGCCATGCCGCTGAGCGCGTTGATGCTGATCGAGT
TCCTGCATGTCCAGAAAGGCGACTGGATTGTGCAAAACACGGCCAACGGCGCGGTTGGCAAGACCGTCGCCATGCTCGCG
GCGGCACGCGACATCAACGTGATCAATCTGGTGCGTCGCGATGCCGGCGTGGACGAACTCAAGGCACTGGGGATCGGGAA
TGCGGTGTCGACCGCGCAGGACGGTTGGCAAGACCGCGTGCGCGCGCTGGCCGGCGATGCACCGATCGTGCGCGCGATCG
ACTCGGTGGCCGGCAAGGCGGCAGGCGAGCTGATGGGGCTGCTTGCCGAGGGCGGCGAGTTGATCTCGTTCGGCTCGATG
ACCGGCGAACCGCTGGAGATTGCCAGCGGCGATGTGATCTTCAAGCAGGCCACCGTGCGCGGCTTCTGGGGCAGCAAGGT
CATGGCCGCCACCAAGTCCGAGGACAAGCGCCGCATGATCGGCGAGCTGTTGAAGGCCGCGCTCGACGGCAACCTGGCGC
TGCCGGTGGAAGCGGTGTTCGATCTGGAAGACGCGGCCAAGGCGGCAGCGGCCAGTGCCGAACCGGGGCGAGGTGGCAAG
GTCCTGCTGCGCGCCGGTTGA

Upstream 100 bases:

>100_bases
TTCGCTTCATCGGGCGCTTGCAGCGTTCCCGTTAGCATCGCAGCACCTTTCACTGTGATCGGCTGCGCTGCATCACGGGC
GCCGCCGACAGGAGACTTGC

Downstream 100 bases:

>100_bases
GCGGGGCGCGCGCCGATCGAAACAGCGCCAGCGCGGGGACGGAGTGGCAGGTCGCCCGCGCTGGCTGGATGGCAGTGTCG
CTTGCGCGGCTGGAACTCTC

Product: putative nuclear receptor binding factor-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRAAIHTRFGDPAKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPTLPAIGGSEGSGVIDALGEGVQDL
QVGQRVVAAGVHESWADYFLAEATGVVPLPDALDDDRGCQLIAMPLSALMLIEFLHVQKGDWIVQNTANGAVGKTVAMLA
AARDINVINLVRRDAGVDELKALGIGNAVSTAQDGWQDRVRALAGDAPIVRAIDSVAGKAAGELMGLLAEGGELISFGSM
TGEPLEIASGDVIFKQATVRGFWGSKVMAATKSEDKRRMIGELLKAALDGNLALPVEAVFDLEDAAKAAAASAEPGRGGK
VLLRAG

Sequences:

>Translated_326_residues
MRAAIHTRFGDPAKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPTLPAIGGSEGSGVIDALGEGVQDL
QVGQRVVAAGVHESWADYFLAEATGVVPLPDALDDDRGCQLIAMPLSALMLIEFLHVQKGDWIVQNTANGAVGKTVAMLA
AARDINVINLVRRDAGVDELKALGIGNAVSTAQDGWQDRVRALAGDAPIVRAIDSVAGKAAGELMGLLAEGGELISFGSM
TGEPLEIASGDVIFKQATVRGFWGSKVMAATKSEDKRRMIGELLKAALDGNLALPVEAVFDLEDAAKAAAASAEPGRGGK
VLLRAG
>Mature_326_residues
MRAAIHTRFGDPAKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPTLPAIGGSEGSGVIDALGEGVQDL
QVGQRVVAAGVHESWADYFLAEATGVVPLPDALDDDRGCQLIAMPLSALMLIEFLHVQKGDWIVQNTANGAVGKTVAMLA
AARDINVINLVRRDAGVDELKALGIGNAVSTAQDGWQDRVRALAGDAPIVRAIDSVAGKAAGELMGLLAEGGELISFGSM
TGEPLEIASGDVIFKQATVRGFWGSKVMAATKSEDKRRMIGELLKAALDGNLALPVEAVFDLEDAAKAAAASAEPGRGGK
VLLRAG

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=330, Percent_Identity=31.2121212121212, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI67078406, Length=296, Percent_Identity=30.7432432432432, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI24308257, Length=254, Percent_Identity=28.740157480315, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI194239674, Length=280, Percent_Identity=26.0714285714286, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI13236495, Length=280, Percent_Identity=26.0714285714286, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI18379349, Length=318, Percent_Identity=22.9559748427673, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=316, Percent_Identity=30.6962025316456, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17556000, Length=334, Percent_Identity=29.0419161676647, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17507255, Length=202, Percent_Identity=29.2079207920792, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319500, Length=316, Percent_Identity=21.8354430379747, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550423, Length=298, Percent_Identity=30.2013422818792, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34154; Mature: 34154

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAIHTRFGDPAKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPTLPA
CCCCEECCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCC
IGGSEGSGVIDALGEGVQDLQVGQRVVAAGVHESWADYFLAEATGVVPLPDALDDDRGCQ
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
LIAMPLSALMLIEFLHVQKGDWIVQNTANGAVGKTVAMLAAARDINVINLVRRDAGVDEL
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
KALGIGNAVSTAQDGWQDRVRALAGDAPIVRAIDSVAGKAAGELMGLLAEGGELISFGSM
HHHCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
TGEPLEIASGDVIFKQATVRGFWGSKVMAATKSEDKRRMIGELLKAALDGNLALPVEAVF
CCCCEEECCCCEEEEEHEECCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
DLEDAAKAAAASAEPGRGGKVLLRAG
CHHHHHHHHHCCCCCCCCCEEEEECC
>Mature Secondary Structure
MRAAIHTRFGDPAKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPTLPA
CCCCEECCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCC
IGGSEGSGVIDALGEGVQDLQVGQRVVAAGVHESWADYFLAEATGVVPLPDALDDDRGCQ
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
LIAMPLSALMLIEFLHVQKGDWIVQNTANGAVGKTVAMLAAARDINVINLVRRDAGVDEL
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
KALGIGNAVSTAQDGWQDRVRALAGDAPIVRAIDSVAGKAAGELMGLLAEGGELISFGSM
HHHCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
TGEPLEIASGDVIFKQATVRGFWGSKVMAATKSEDKRRMIGELLKAALDGNLALPVEAVF
CCCCEEECCCCEEEEEHEECCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
DLEDAAKAAAASAEPGRGGKVLLRAG
CHHHHHHHHHCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]