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The map label for this gene is coaX [H]

Identifier: 78049665

GI number: 78049665

Start: 4704298

End: 4705026

Strand: Reverse

Name: coaX [H]

Synonym: XCV4109

Alternate gene names: 78049665

Gene position: 4705026-4704298 (Counterclockwise)

Preceding gene: 162138528

Following gene: 78049664

Centisome position: 90.86

GC content: 71.88

Gene sequence:

>729_bases
ATGAGCGAGTGGTTGTTCGACCTGGGAAATTCGCGCTTCAAGTACGCGCCGCTGCACGGCAACCGTGCCGGCCAGGTGCA
GGCGTGGGCGCATGGCGCCGAGGCGATGGACGCGGCGGCGCTGGCGGCGCTGCCGTCCGGGCGTATTGCGTATGTCGCCA
GCGTGGCAGCGCCGGCATTGACGCAACCCATGATCGCCTGCCTGCAGGAGCGCTTTACGCAGGTGCGCATCGTGCGGACC
ACCGCCGAATGCGCCGGCGTCCGGATTGCTTATGCCGACCCGAGCCGCTTCGGCGTGGACCGCTTTCTGGCGTTGCTGGG
TGCGCGGGGCGATGCGCCGGTGCTGGTGGCCGGCGTGGGCACCGCACTGACCATCGACGTGCTCGGCGCCGATGGCCTGC
ACCACGGCGGCCGCATCGCCGCCTCGCCGACCACCATGCGCGAAGCGCTGCATGCGCGCGCGGTGCAACTGCCGGCCAGC
GGCGGCGATTACGTCGAGCTGGCCATCGACACCGACGATGCCTTGACCTCCGGCTGCGATGGCGCGGCGGTGGCGCTGAT
CGAGCGCAGCCTGCAGCACGCCCAACGCAGCCTGGGCGTTCCGGTGCGGCTGCTGGTGCATGGCGGTGGCGCGCCGCCGT
TGCTGCCTCTGCTGCCCGATGCCTCGTTCCGCGCGGCCCTGGTGCTGGACGGTCTGGCGACGTGGGCGACCGCTGCGGCG
TCCCCGTAG

Upstream 100 bases:

>100_bases
GTGGCGTCGCGCTCGGCCTGGCGGCCGATGGTGCGTTGCGGGTGCAACTGGGCGAGACGGTGCGACTGTTCCACTCCGGG
GAAGTGAGCGTGAGACCTGC

Downstream 100 bases:

>100_bases
AATCGGCGCATGTATGTTCGCGCGCTCATCGTCGTCTTGATCGTCCTCAATGCCGGGGTGGCGTTGTGGTGGGCCTTGCA
GCCGCCACCGGCACCACCGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGRIAYVASVAAPALTQPMIACLQERFTQVRIVRT
TAECAGVRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGRIAASPTTMREALHARAVQLPAS
GGDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGVPVRLLVHGGGAPPLLPLLPDASFRAALVLDGLATWATAAA
SP

Sequences:

>Translated_242_residues
MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGRIAYVASVAAPALTQPMIACLQERFTQVRIVRT
TAECAGVRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGRIAASPTTMREALHARAVQLPAS
GGDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGVPVRLLVHGGGAPPLLPLLPDASFRAALVLDGLATWATAAA
SP
>Mature_241_residues
SEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGRIAYVASVAAPALTQPMIACLQERFTQVRIVRTT
AECAGVRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGRIAASPTTMREALHARAVQLPASG
GDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGVPVRLLVHGGGAPPLLPLLPDASFRAALVLDGLATWATAAAS
P

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 24942; Mature: 24811

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGRIAYVASVAAPAL
CCCCHHHCCCCCEEEECCCCCCCCCEEHHHCCHHHHHHHHHHHCCCCCEEEEEHHHHHHH
TQPMIACLQERFTQVRIVRTTAECAGVRIAYADPSRFGVDRFLALLGARGDAPVLVAGVG
HHHHHHHHHHHHHEEEEEEEEHHHHCEEEEECCCCHHCHHHHHHHHCCCCCCCEEEEECC
TALTIDVLGADGLHHGGRIAASPTTMREALHARAVQLPASGGDYVELAIDTDDALTSGCD
CEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHEECCCCCCCEEEEEEECCHHHHCCCC
GAAVALIERSLQHAQRSLGVPVRLLVHGGGAPPLLPLLPDASFRAALVLDGLATWATAAA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SP
CC
>Mature Secondary Structure 
SEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGRIAYVASVAAPAL
CCCHHHCCCCCEEEECCCCCCCCCEEHHHCCHHHHHHHHHHHCCCCCEEEEEHHHHHHH
TQPMIACLQERFTQVRIVRTTAECAGVRIAYADPSRFGVDRFLALLGARGDAPVLVAGVG
HHHHHHHHHHHHHEEEEEEEEHHHHCEEEEECCCCHHCHHHHHHHHCCCCCCCEEEEECC
TALTIDVLGADGLHHGGRIAASPTTMREALHARAVQLPASGGDYVELAIDTDDALTSGCD
CEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHEECCCCCCCEEEEEEECCHHHHCCCC
GAAVALIERSLQHAQRSLGVPVRLLVHGGGAPPLLPLLPDASFRAALVLDGLATWATAAA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]