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The map label for this gene is ntrC [H]

Identifier: 78049408

GI number: 78049408

Start: 4436259

End: 4437713

Strand: Reverse

Name: ntrC [H]

Synonym: XCV3852

Alternate gene names: 78049408

Gene position: 4437713-4436259 (Counterclockwise)

Preceding gene: 78049412

Following gene: 78049407

Centisome position: 85.7

GC content: 64.74

Gene sequence:

>1455_bases
ATGCGTACTTCGCCCACAGCCGTCAGGGCGGGCTCGACCGGGGGAGGAGCGCCGCACCATCTACAGAACGTGACAGCAGC
AGGCAATTTCCGATGTGGTGTGCAGCGCATTTCGCGCGGCCGTCACAATTCTCAACTGAACATGTATCAGTCATTGCGGA
CAGAAGCGCTCATGGACCGTCTTTCCTGCGCCATCATCGACGACGACGTGGAGTTCTGCGATCAGGTGGTTGAACTCGCC
ACCGATAGCGGCTTCCGTGCCAAGGGCATCCACACCCTTGGCGAAGCCAGCCGCTGGCTGGACAGCAACTTTCCCGACCT
GTTGGTGGTGGATGTTGGCCTGCCGGACGGCAGCGGTTTCGACCTGATCGAACGGCTCGACCCGGACCACACCCCGCAGA
TCGTTGTGGTCTCGGGCGATTACGCGCGCGAAACCCAGGGTCGCGCGCAGCAGTTCGGGGTCAGCGAATTCCTGACCAAG
CCGTTCGCGCCCGAACGCCTGGAGCGGGTGCTCGGGGGACTGCGCGAAGCGCAGCAGGGCAACCTGGGCATCGTTGGCAA
CAGCGACAGCATCGTCATGCTGCGCAAGGACATCGTGCGCGTGGCGCCGACCGATCTGAATGTACTGGTGACCGGCGAAA
CCGGTACCGGCAAGGATCTGGTGGCGCGCGCCATCCACCGTGTGTCCGGTCGCCGCGGCCGTTTCGTGCCGGTCAACTGC
GGTGCCATTCCGGAAGAGTTGCTGGCCAGCCAGTTGTTCGGCCACGAGCGCGGCAGCTTCACCGGCGCCGACCGTCGGCA
TGCCGGATTCCTGGAGCAGGCCGCAGGCGGCACGCTGTTCCTGGATGAAATCGGCGAGATGCCCAAGCGGCTGCAGGTGT
ATCTGCTGCGGGCGATCGAATCGCGCAGCTTCATGCGCGTGGGCGGCAACGAGGAAATCGCACTGGATGCGCGCGTGGTG
GCAGCCACCCACCAGCACGTGCAGCGCGAGCAGGCGGTGCTGCGCGAAGACCTGTTCTACCGCCTCAATGAATACCCGAT
CCAGGTGCCGCCGCTGCGCGAGCGCCGCGGCGATGCGCGCCTGCTTGGCTTACGCGTGATCGACGAGCTCAACGTCAAGT
ATGGCAAGCGCAAGTTGCCGACCAAGTCGTTGCTGCGCTACCTGGCCTACCATGCCTGGCCAGGCAACGTGCGCGAGCTG
CGCTCGTTCATCCACTACCTTTATCTGCGCTCCGATGGCGATCTGTTGAGCGCCCCGGATGTGGAGCAGACCGTGCCGCA
GGCCGACCAGGACGGCTTGCTGATTCCTGCCGGCTGGACCATGCGCCAGGCCGAAGATGCGATGATCGAATCGGCACTGG
CGCGCACCCGCTTCAACAAGAAGGCCGCCGCACGCGAACTGGGCATCAGCGTGCGCACCCTGCACAACCGGCTCAGCGAC
AAGGGTGCGGAGTGA

Upstream 100 bases:

>100_bases
GCGGCCCTGGCAAACCTTGCTCTCCTTGGCGTTTCGGCGTTCTCGAAGCGGCGACCGACCCAGAGCGTGACGCTTGGCAC
TGGCGCAATCGAGCGCTTCC

Downstream 100 bases:

>100_bases
GCGAGGCACCGCGTGGGCAGCGGCGCGAGCTGCTGCACCAGTTGCGCAACCGGCTCAACGTGATGGGTTTTGCGTTGTAT
GCGTTGCGCAACGAAACGTC

Product: sigma-54 dependent response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MRTSPTAVRAGSTGGGAPHHLQNVTAAGNFRCGVQRISRGRHNSQLNMYQSLRTEALMDRLSCAIIDDDVEFCDQVVELA
TDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGFDLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTK
PFAPERLERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHRVSGRRGRFVPVNC
GAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLRAIESRSFMRVGGNEEIALDARVV
AATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRVIDELNVKYGKRKLPTKSLLRYLAYHAWPGNVREL
RSFIHYLYLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAARELGISVRTLHNRLSD
KGAE

Sequences:

>Translated_484_residues
MRTSPTAVRAGSTGGGAPHHLQNVTAAGNFRCGVQRISRGRHNSQLNMYQSLRTEALMDRLSCAIIDDDVEFCDQVVELA
TDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGFDLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTK
PFAPERLERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHRVSGRRGRFVPVNC
GAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLRAIESRSFMRVGGNEEIALDARVV
AATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRVIDELNVKYGKRKLPTKSLLRYLAYHAWPGNVREL
RSFIHYLYLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAARELGISVRTLHNRLSD
KGAE
>Mature_484_residues
MRTSPTAVRAGSTGGGAPHHLQNVTAAGNFRCGVQRISRGRHNSQLNMYQSLRTEALMDRLSCAIIDDDVEFCDQVVELA
TDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGFDLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTK
PFAPERLERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHRVSGRRGRFVPVNC
GAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLRAIESRSFMRVGGNEEIALDARVV
AATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRVIDELNVKYGKRKLPTKSLLRYLAYHAWPGNVREL
RSFIHYLYLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAARELGISVRTLHNRLSD
KGAE

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=35.3603603603604, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1788550, Length=410, Percent_Identity=34.390243902439, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1790299, Length=472, Percent_Identity=32.4152542372881, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1789233, Length=315, Percent_Identity=40.6349206349206, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1789087, Length=314, Percent_Identity=40.1273885350318, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1788905, Length=375, Percent_Identity=34.1333333333333, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI87082117, Length=281, Percent_Identity=41.2811387900356, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786524, Length=319, Percent_Identity=41.0658307210031, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87082152, Length=309, Percent_Identity=39.4822006472492, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI87081872, Length=311, Percent_Identity=35.048231511254, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787583, Length=320, Percent_Identity=34.6875, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789828, Length=205, Percent_Identity=35.1219512195122, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081858, Length=225, Percent_Identity=33.7777777777778, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53614; Mature: 53614

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSPTAVRAGSTGGGAPHHLQNVTAAGNFRCGVQRISRGRHNSQLNMYQSLRTEALMDR
CCCCCCEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LSCAIIDDDVEFCDQVVELATDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGF
HHHEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
DLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQG
HHHHHCCCCCCCEEEEEECCCHHHHCCHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCC
NLGIVGNSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHRVSGRRGRFVPVNC
CEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEC
GAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLRAIE
CCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEHHHHHCCHHHHHHHHHHHHH
SRSFMRVGGNEEIALDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDAR
CCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCE
LLGLRVIDELNVKYGKRKLPTKSLLRYLAYHAWPGNVRELRSFIHYLYLRSDGDLLSAPD
EEHHHHHHHHCHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
VEQTVPQADQDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAARELGISVRTLHNRLSD
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
KGAE
CCCC
>Mature Secondary Structure
MRTSPTAVRAGSTGGGAPHHLQNVTAAGNFRCGVQRISRGRHNSQLNMYQSLRTEALMDR
CCCCCCEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LSCAIIDDDVEFCDQVVELATDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGF
HHHEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
DLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQG
HHHHHCCCCCCCEEEEEECCCHHHHCCHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCC
NLGIVGNSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHRVSGRRGRFVPVNC
CEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEC
GAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLRAIE
CCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEHHHHHCCHHHHHHHHHHHHH
SRSFMRVGGNEEIALDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDAR
CCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCE
LLGLRVIDELNVKYGKRKLPTKSLLRYLAYHAWPGNVRELRSFIHYLYLRSDGDLLSAPD
EEHHHHHHHHCHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
VEQTVPQADQDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAARELGISVRTLHNRLSD
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
KGAE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]