Click here to switch to the map view.

The map label for this gene is wzt [H]

Identifier: 78049277

GI number: 78049277

Start: 4300922

End: 4302208

Strand: Reverse

Name: wzt [H]

Synonym: XCV3721

Alternate gene names: 78049277

Gene position: 4302208-4300922 (Counterclockwise)

Preceding gene: 78049278

Following gene: 78049276

Centisome position: 83.08

GC content: 57.5

Gene sequence:

>1287_bases
ATGAGCGATGTCGTAATGCGTGTTGAGGACGTTGGCAAGGCCTATCGGGTCTGGAGCAGTCAATGGTTGCGGGCGGCCAG
TTGGTTCGGTGCTCCAGTGCAGGCGCGCGAGGAACATTGGATCCTGCGCAATGTGTCGTTTTCGATCAAGACCGGCGAAT
CCGTTGGCGTAGTGGGGCGCAACGGTGCGGGTAAAAGTACGCTGCTGAAACTGATCACCGGAACCGTGCAGCCTACTGAA
GGCGTCATTGCCCGGTCGGGGCGAATCGCGGCGATCCTGGAGCTGGGCATGGGATTCAACCCGGACCTGACAGGCAGGCA
GAATGCGTACCATTCAGCAGGTTTGATGGGGTACTCTCAACAGCAAATCGATGCGGCCATGCCCGGCATCGAGCGGTTCG
CCGAGGTTGGAGAATACTTCGATACGCCAGTGCGGACCTACTCCAGCGGAATGCAGGTGCGGGTGGCATTCGCCGTAGCG
ACGGCGTTCCGCCCCGACGTGTTGATCGTCGATGAGGCGCTTTCTGTGGGAGACGCCTATTTTCAGGCGAAGTGCTTCAA
GCGCGTCCAGGAATTCAAGGAGCTGGGAACCACATTGATCCTGGTGAGTCATGCAGTGGGTGACATCGTCAAGCACTGCG
AGCGCGTGCTATTCATCAAAGATGGCGGCGTCTATGCCGACGGCCCGGCGCGTGAAGTTTCCAATCTTTATCTGGACGAG
CTTTTTGGGCGAAAGAGCAGTCCTGATTCTGCGCGTGCGGACGTTCCGATCAAAGCGATCCCAGGCGAAAGCATCGATGA
CGTATTCCACACTCGCCCTTTGTATAACCGCAACGAGCATCGTTGGGGTCAGGGCGGAGCGAAGATCGTCGACTATGCGG
TGACCAGTAGTGGCGAGCGTTTTCCCGCGCGTATCGACAGCGGTGCGGTCACGAAATTCCACATGAAGATCTTTTTCGAG
CGTGACTTTGACAACGTGGTCCCAGGTCTGTTGTTGAAGACGCTCGAAGGGCTGTTCCTCTATGGGACAAATTCATTTTT
GGCGAGCGACGGGCGGAAGATGCTTTCCCCACGCGCAGGCGATGTGATTACCTGCCATTTCGCATTGCCGCTGAGCGTCA
ATGAGGGGCATTACATGGTGTCGTTGGGGGTGTCGAGCGGCGATCCGCTCGGCGAGTTGGTGCCCCTGGACAGGCGCTAT
GATTCCATCTTGCTGGATGTCAGCCGTCCCATGCAGTTCTGGGGCATCGTTGACTTGAATGCCGAATTTTCCGCCGACGT
TTCTTGA

Upstream 100 bases:

>100_bases
ATTGGCGCTCATTGATGCCGCTATGTGCGGCCACTGCGATACTGGGCCTGATGTCGTTAGTGGTGTTCCGACGTGCCAGT
CAAGAAATGGTGGATGCGCT

Downstream 100 bases:

>100_bases
TTGCCGTCCGTGTCCGCGCCGCCGGCGTGCCGCTAATTCCAGGTTTCTATTGATGACGCATTCCGTTTCCCCGGGCAACA
GTTCTATCGCCGATCTCGTT

Product: O-antigen ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSDVVMRVEDVGKAYRVWSSQWLRAASWFGAPVQAREEHWILRNVSFSIKTGESVGVVGRNGAGKSTLLKLITGTVQPTE
GVIARSGRIAAILELGMGFNPDLTGRQNAYHSAGLMGYSQQQIDAAMPGIERFAEVGEYFDTPVRTYSSGMQVRVAFAVA
TAFRPDVLIVDEALSVGDAYFQAKCFKRVQEFKELGTTLILVSHAVGDIVKHCERVLFIKDGGVYADGPAREVSNLYLDE
LFGRKSSPDSARADVPIKAIPGESIDDVFHTRPLYNRNEHRWGQGGAKIVDYAVTSSGERFPARIDSGAVTKFHMKIFFE
RDFDNVVPGLLLKTLEGLFLYGTNSFLASDGRKMLSPRAGDVITCHFALPLSVNEGHYMVSLGVSSGDPLGELVPLDRRY
DSILLDVSRPMQFWGIVDLNAEFSADVS

Sequences:

>Translated_428_residues
MSDVVMRVEDVGKAYRVWSSQWLRAASWFGAPVQAREEHWILRNVSFSIKTGESVGVVGRNGAGKSTLLKLITGTVQPTE
GVIARSGRIAAILELGMGFNPDLTGRQNAYHSAGLMGYSQQQIDAAMPGIERFAEVGEYFDTPVRTYSSGMQVRVAFAVA
TAFRPDVLIVDEALSVGDAYFQAKCFKRVQEFKELGTTLILVSHAVGDIVKHCERVLFIKDGGVYADGPAREVSNLYLDE
LFGRKSSPDSARADVPIKAIPGESIDDVFHTRPLYNRNEHRWGQGGAKIVDYAVTSSGERFPARIDSGAVTKFHMKIFFE
RDFDNVVPGLLLKTLEGLFLYGTNSFLASDGRKMLSPRAGDVITCHFALPLSVNEGHYMVSLGVSSGDPLGELVPLDRRY
DSILLDVSRPMQFWGIVDLNAEFSADVS
>Mature_427_residues
SDVVMRVEDVGKAYRVWSSQWLRAASWFGAPVQAREEHWILRNVSFSIKTGESVGVVGRNGAGKSTLLKLITGTVQPTEG
VIARSGRIAAILELGMGFNPDLTGRQNAYHSAGLMGYSQQQIDAAMPGIERFAEVGEYFDTPVRTYSSGMQVRVAFAVAT
AFRPDVLIVDEALSVGDAYFQAKCFKRVQEFKELGTTLILVSHAVGDIVKHCERVLFIKDGGVYADGPAREVSNLYLDEL
FGRKSSPDSARADVPIKAIPGESIDDVFHTRPLYNRNEHRWGQGGAKIVDYAVTSSGERFPARIDSGAVTKFHMKIFFER
DFDNVVPGLLLKTLEGLFLYGTNSFLASDGRKMLSPRAGDVITCHFALPLSVNEGHYMVSLGVSSGDPLGELVPLDRRYD
SILLDVSRPMQFWGIVDLNAEFSADVS

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=222, Percent_Identity=29.2792792792793, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI6005701, Length=210, Percent_Identity=27.1428571428571, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI31657092, Length=220, Percent_Identity=28.6363636363636, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI27477115, Length=210, Percent_Identity=27.1428571428571, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI27436953, Length=206, Percent_Identity=24.7572815533981, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI30795238, Length=204, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27881501, Length=204, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI150417984, Length=190, Percent_Identity=27.3684210526316, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI105990541, Length=202, Percent_Identity=25.2475247524752, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI116734710, Length=204, Percent_Identity=25.4901960784314, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI89111135, Length=202, Percent_Identity=23.2673267326733, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27262624, Length=206, Percent_Identity=22.8155339805825, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI27262626, Length=206, Percent_Identity=22.8155339805825, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI45446740, Length=253, Percent_Identity=23.3201581027668, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI47078218, Length=253, Percent_Identity=23.3201581027668, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI157502201, Length=228, Percent_Identity=28.5087719298246, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI157502203, Length=230, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787758, Length=241, Percent_Identity=29.4605809128631, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789891, Length=212, Percent_Identity=27.3584905660377, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.5825242718447, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788165, Length=212, Percent_Identity=27.8301886792453, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787164, Length=198, Percent_Identity=34.8484848484849, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787089, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786398, Length=208, Percent_Identity=26.4423076923077, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081709, Length=204, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994943, Length=207, Percent_Identity=27.536231884058, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790525, Length=229, Percent_Identity=26.2008733624454, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=220, Percent_Identity=27.7272727272727, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788210, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789873, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790544, Length=235, Percent_Identity=25.1063829787234, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789032, Length=218, Percent_Identity=24.7706422018349, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082267, Length=211, Percent_Identity=27.0142180094787, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787370, Length=204, Percent_Identity=23.0392156862745, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786703, Length=206, Percent_Identity=29.6116504854369, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081834, Length=246, Percent_Identity=27.6422764227642, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787712, Length=299, Percent_Identity=25.4180602006689, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790467, Length=249, Percent_Identity=26.1044176706827, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788897, Length=205, Percent_Identity=23.9024390243902, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786253, Length=221, Percent_Identity=26.6968325791855, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=220, Percent_Identity=24.0909090909091, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081782, Length=202, Percent_Identity=26.2376237623762, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=205, Percent_Identity=24.390243902439, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=210, Percent_Identity=24.2857142857143, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569081, Length=216, Percent_Identity=27.3148148148148, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992066, Length=216, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71992070, Length=216, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI86564969, Length=216, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25146765, Length=216, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565586, Length=210, Percent_Identity=22.8571428571429, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=215, Percent_Identity=27.4418604651163, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=204, Percent_Identity=25, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=204, Percent_Identity=25, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=201, Percent_Identity=25.3731343283582, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007184, Length=197, Percent_Identity=29.9492385786802, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221500365, Length=197, Percent_Identity=29.9492385786802, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666092, Length=205, Percent_Identity=27.3170731707317, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221512771, Length=205, Percent_Identity=22.9268292682927, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643674, Length=208, Percent_Identity=22.5961538461538, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 47002; Mature: 46871

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVVMRVEDVGKAYRVWSSQWLRAASWFGAPVQAREEHWILRNVSFSIKTGESVGVVGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCCEEEEEEC
NGAGKSTLLKLITGTVQPTEGVIARSGRIAAILELGMGFNPDLTGRQNAYHSAGLMGYSQ
CCCCHHHHHHHHHCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCH
QQIDAAMPGIERFAEVGEYFDTPVRTYSSGMQVRVAFAVATAFRPDVLIVDEALSVGDAY
HHHHHHCCHHHHHHHHHHHHCCCHHHHCCCCEEEEEEEEHHHCCCCEEEEECHHHHHHHH
FQAKCFKRVQEFKELGTTLILVSHAVGDIVKHCERVLFIKDGGVYADGPAREVSNLYLDE
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCEEEEEECCCEECCCCHHHHHHHHHHH
LFGRKSSPDSARADVPIKAIPGESIDDVFHTRPLYNRNEHRWGQGGAKIVDYAVTSSGER
HHCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
FPARIDSGAVTKFHMKIFFERDFDNVVPGLLLKTLEGLFLYGTNSFLASDGRKMLSPRAG
CCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHCCEEEEECCHHHHCCCHHHCCCCCC
DVITCHFALPLSVNEGHYMVSLGVSSGDPLGELVPLDRRYDSILLDVSRPMQFWGIVDLN
CEEEEEEEEEEEECCCEEEEEEECCCCCCCHHCCCCCCCCCEEEEECCCCCEEEEEEECC
AEFSADVS
CCCCCCCC
>Mature Secondary Structure 
SDVVMRVEDVGKAYRVWSSQWLRAASWFGAPVQAREEHWILRNVSFSIKTGESVGVVGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCCEEEEEEC
NGAGKSTLLKLITGTVQPTEGVIARSGRIAAILELGMGFNPDLTGRQNAYHSAGLMGYSQ
CCCCHHHHHHHHHCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCH
QQIDAAMPGIERFAEVGEYFDTPVRTYSSGMQVRVAFAVATAFRPDVLIVDEALSVGDAY
HHHHHHCCHHHHHHHHHHHHCCCHHHHCCCCEEEEEEEEHHHCCCCEEEEECHHHHHHHH
FQAKCFKRVQEFKELGTTLILVSHAVGDIVKHCERVLFIKDGGVYADGPAREVSNLYLDE
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCEEEEEECCCEECCCCHHHHHHHHHHH
LFGRKSSPDSARADVPIKAIPGESIDDVFHTRPLYNRNEHRWGQGGAKIVDYAVTSSGER
HHCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
FPARIDSGAVTKFHMKIFFERDFDNVVPGLLLKTLEGLFLYGTNSFLASDGRKMLSPRAG
CCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHCCEEEEECCHHHHCCCHHHCCCCCC
DVITCHFALPLSVNEGHYMVSLGVSSGDPLGELVPLDRRYDSILLDVSRPMQFWGIVDLN
CEEEEEEEEEEEECCCEEEEEEECCCCCCCHHCCCCCCCCCEEEEECCCCCEEEEEEECC
AEFSADVS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]