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The map label for this gene is wxcI [H]

Identifier: 78049258

GI number: 78049258

Start: 4276838

End: 4277569

Strand: Reverse

Name: wxcI [H]

Synonym: XCV3702

Alternate gene names: 78049258

Gene position: 4277569-4276838 (Counterclockwise)

Preceding gene: 78049261

Following gene: 78049257

Centisome position: 82.6

GC content: 62.7

Gene sequence:

>732_bases
ATGCGCAGTGACGGACGCGGTGCGGCAAGCGGCAAACGCTATGCCGATGCCAAGGCAGCACTGGACGGGGTACTGGCCAA
TGGTCAGACCCTGGCGGTGGGCGGCTTTGGGTTGTGTGGAATCCCGGAGGCATTGATTGCAGCCGTGCGCGACAGTGGGA
TCGGCGGGTTGACGGTGATCTCGAACAACGCCGGCGTCGACGGATTCGGGCTTGGTCAATTATTGGCCACCCGGCAGATC
CGCAAGATGATTTCGTCCTACGTGGGCGAAAACAAGGAATTCGAACGCCAATACCTGGCGGGCGAACTCGAGCTGGAGTT
CAATCCGCAAGGCACCCTGGCCGAGCGTTTGCGCGCCGGTGGCGCGGGCATTCCTGCGTTTTACACCGCCACCGGCTACG
GCACGATCGTGGCCCAGGGCAAGGAAACGCGCGAATTCGACGGCAAGCATTACGTGCTTGAAACCGCGTTGCAGGCCGAC
GTGGCGTTGGTCAAGGCATGGCGCGCCGATACCGCCGGCAACCTGGTATTCCGTAAGACCGCGCGCAATTTCAATCCCGC
CTGCGCCATGGCCGGACGCGTGTGCATCGCCGAGGTCGAGGACATCGTGGAGCTGGGCGTTATCGATCCGGATCAGGTGC
ATCTGCCCGGCATTTACGTGGACCGCCTGGTGCTCAACGCCACGCCGGAAAAACGCATCGAACAGCGCACCGTGCGCGAA
GGACAGCAGTGA

Upstream 100 bases:

>100_bases
GCGGCTGCGCCGTGTCTTGGGTGTGGCGGAATTGCGACCGGGGACAGGGAACAGTCAGCGGATAGAATGGGCGCTTCACA
TCAGCGAGGTGAGGGCGGTG

Downstream 100 bases:

>100_bases
TGGCCTGGACCAGAGACCAGATGGCCGCACGCGCGGCACGCGAACTGACCGATGGTGCCTACGTCAACCTGGGCATCGGC
CTGCCGACGCTGGTCGCCAA

Product: 3-oxoacid CoA transferase alpha subunit

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRSDGRGAASGKRYADAKAALDGVLANGQTLAVGGFGLCGIPEALIAAVRDSGIGGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIPAFYTATGYGTIVAQGKETREFDGKHYVLETALQAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ

Sequences:

>Translated_243_residues
MRSDGRGAASGKRYADAKAALDGVLANGQTLAVGGFGLCGIPEALIAAVRDSGIGGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIPAFYTATGYGTIVAQGKETREFDGKHYVLETALQAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ
>Mature_243_residues
MRSDGRGAASGKRYADAKAALDGVLANGQTLAVGGFGLCGIPEALIAAVRDSGIGGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIPAFYTATGYGTIVAQGKETREFDGKHYVLETALQAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=54.6558704453441, Blast_Score=279, Evalue=1e-75,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=53.469387755102, Blast_Score=246, Evalue=2e-65,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=41.6666666666667, Blast_Score=181, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=56.5573770491803, Blast_Score=266, Evalue=7e-72,
Organism=Drosophila melanogaster, GI21358325, Length=251, Percent_Identity=47.808764940239, Blast_Score=240, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24655794, Length=251, Percent_Identity=47.808764940239, Blast_Score=240, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25883; Mature: 25883

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSDGRGAASGKRYADAKAALDGVLANGQTLAVGGFGLCGIPEALIAAVRDSGIGGLTVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEE
SNNAGVDGFGLGQLLATRQIRKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCC
GAGIPAFYTATGYGTIVAQGKETREFDGKHYVLETALQADVALVKAWRADTAGNLVFRKT
CCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
ARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
CCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCEEEHHHEECCCCHHHHHHHHHHC
GQQ
CCC
>Mature Secondary Structure
MRSDGRGAASGKRYADAKAALDGVLANGQTLAVGGFGLCGIPEALIAAVRDSGIGGLTVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEE
SNNAGVDGFGLGQLLATRQIRKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCC
GAGIPAFYTATGYGTIVAQGKETREFDGKHYVLETALQADVALVKAWRADTAGNLVFRKT
CCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
ARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
CCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCEEEHHHEECCCCHHHHHHHHHHC
GQQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]