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The map label for this gene is xerD [H]

Identifier: 78049232

GI number: 78049232

Start: 4245687

End: 4246658

Strand: Reverse

Name: xerD [H]

Synonym: XCV3676

Alternate gene names: 78049232

Gene position: 4246658-4245687 (Counterclockwise)

Preceding gene: 78049234

Following gene: 78049231

Centisome position: 82.01

GC content: 68.31

Gene sequence:

>972_bases
ATGTCTGCCAGCAGTCCCGCCGAACGCCGCCAACTTGCCCGCCAGCTGCCACCGGTGCAGGCGGCCGATGCCAGCGTGAT
CGAACGGTTTCTCGACCGGTTCTGGGCCGAGCAAGGCGTGGCGCGGCAGACCCTGGAGAGTTATCGGCGCGACCTGGAAG
GGCTGGCGCGTTGGCGCGACGGCGCACATGGTGGCTTGCTCGGCATCGACCGTGCCGCCCTGTTCGACTATCTGCGCTGG
CGTACCCAGGCCAATTATTCCCCGCGCAGCACGGCGCGGCTGTTGTCGACCTTGCGTGCGTTCTACGGGCTGTGCCTGCG
CGATGGCGTGCGCAGCGACGACCCCACCACCCTGATCGATCCGCCGCAACTGCCACGCTCGCTGCCCAAGGCCTTGACCG
AAAGTCAGATCGAGGCCTTGCTGGCCGCGCCGGACGTTGACACCCCGGCAGGCCTGCGCAATCGCGCCATGCTGGAGTTG
ATGTACGCCGCGGGCCTGCGTGTGAGCGAGCTGGTCAACCTGCCGGCAGTGGGGGTGAACCTGCGCCAGGGCGTGCTGCG
GGTGACCGGCAAGGGCAGCAAGGACCGGCTGGTGCCGCTGGGCGAGGAGTCCCAGCATTGGCTGGAGCGTTACCTGCGCG
AGGCGCGCCCGCTGCTGGCCGCGAACAAGCCGGTGGCGGCGGTGGACGGGCAGGTGCCATTGTTCATCGACGCCGCGCGC
CGGCCGCTCAGCCGACAGCAGTTCTGGGCGTTGGTCAAACGCTATGCAGCAGTCGCGGGTATCGACCCGGACACGGTCAG
CCCGCACGGGCTGCGCCACAGCTTTGCCACCCATCTGCTCAACCATGGCGCCGACCTGCGCGCGTTGCAGATGCTGCTGG
GCCATAGCTCGTTGTCGACCACCCAGATCTACACGCTGGTGGCGCGCCAGCATCTGCAGAAACTGCACGCCAGCCATCAT
CCGCGCGGTTAG

Upstream 100 bases:

>100_bases
TGACGCGCACATCTACCGCCCCGCGCGCGCAGGCAACACACCTACCGGCAACCCACGCGCATCGGCGCTCAAAACGCGCG
CCGCGTTTTATGCTGTGGCG

Downstream 100 bases:

>100_bases
TCGGCCCAGCGCCCTGCCATGCGCATGCGTGCCGGCGACGCACCTGTCGCGGTTGCGGCAGAACTGCCAACAGGTCATCG
CCGCGCTGGCGGCCGCACCA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSASSPAERRQLARQLPPVQAADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRDGAHGGLLGIDRAALFDYLRW
RTQANYSPRSTARLLSTLRAFYGLCLRDGVRSDDPTTLIDPPQLPRSLPKALTESQIEALLAAPDVDTPAGLRNRAMLEL
MYAAGLRVSELVNLPAVGVNLRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDAAR
RPLSRQQFWALVKRYAAVAGIDPDTVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLSTTQIYTLVARQHLQKLHASHH
PRG

Sequences:

>Translated_323_residues
MSASSPAERRQLARQLPPVQAADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRDGAHGGLLGIDRAALFDYLRW
RTQANYSPRSTARLLSTLRAFYGLCLRDGVRSDDPTTLIDPPQLPRSLPKALTESQIEALLAAPDVDTPAGLRNRAMLEL
MYAAGLRVSELVNLPAVGVNLRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDAAR
RPLSRQQFWALVKRYAAVAGIDPDTVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLSTTQIYTLVARQHLQKLHASHH
PRG
>Mature_322_residues
SASSPAERRQLARQLPPVQAADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRDGAHGGLLGIDRAALFDYLRWR
TQANYSPRSTARLLSTLRAFYGLCLRDGVRSDDPTTLIDPPQLPRSLPKALTESQIEALLAAPDVDTPAGLRNRAMLELM
YAAGLRVSELVNLPAVGVNLRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDAARR
PLSRQQFWALVKRYAAVAGIDPDTVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLSTTQIYTLVARQHLQKLHASHHP
RG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=49.8338870431894, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=34.1137123745819, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1790767, Length=186, Percent_Identity=29.5698924731183, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790768, Length=183, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35875; Mature: 35743

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSPAERRQLARQLPPVQAADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRD
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GAHGGLLGIDRAALFDYLRWRTQANYSPRSTARLLSTLRAFYGLCLRDGVRSDDPTTLID
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PPQLPRSLPKALTESQIEALLAAPDVDTPAGLRNRAMLELMYAAGLRVSELVNLPAVGVN
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCH
LRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDAAR
HHHCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEHHHC
RPLSRQQFWALVKRYAAVAGIDPDTVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLST
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
TQIYTLVARQHLQKLHASHHPRG
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SASSPAERRQLARQLPPVQAADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRD
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GAHGGLLGIDRAALFDYLRWRTQANYSPRSTARLLSTLRAFYGLCLRDGVRSDDPTTLID
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PPQLPRSLPKALTESQIEALLAAPDVDTPAGLRNRAMLELMYAAGLRVSELVNLPAVGVN
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCH
LRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDAAR
HHHCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEHHHC
RPLSRQQFWALVKRYAAVAGIDPDTVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLST
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
TQIYTLVARQHLQKLHASHHPRG
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]