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The map label for this gene is 78049227

Identifier: 78049227

GI number: 78049227

Start: 4234215

End: 4236098

Strand: Reverse

Name: 78049227

Synonym: XCV3671

Alternate gene names: NA

Gene position: 4236098-4234215 (Counterclockwise)

Preceding gene: 78049228

Following gene: 78049226

Centisome position: 81.8

GC content: 66.72

Gene sequence:

>1884_bases
GTGATCCAGAGTTCTTCTACGCAGGTCCTTGTGCTTGCCTGCTGTGTCCTGGCGGCGTCGTGCAGTACAGCGTTGGCCGC
CAACCCCAACGCCAACGCCGATGCGGCAGCAGCCAATGCCCAACGCCAACAGGCCATGGCCAATGCGCCGGTTGACAGAA
TCATCGTCCGCTACCGCAGCGGGCAGGTCGGTACCGCGCGCGATATCGGCCGCAGTGCCTCGGCGGCAGTCAGTGCGGCC
GCCTCGCGCGCATCCGTCCGTCTTGCGCCTGCCGCACGCACCAGTGCCACCGCAGCGCCAACCTATCTGCGCACGCTTGC
CGCGGGCGGTGAACTGATCAAATTGCCTGCCCAGCTCAGTCGTGCCGATGCCGACCGGCTTGTGCAGGAATTGAGCGCAG
ACCCGGCGGTCGAATCGGCGCAGGTGGATCTGCGCATGTATCCGCTGCAAACCAGCGGCGCATTGCCGAACGACCCGCTG
CTGCAAACCAATCAATGGCATCTCATCGACCCGGTGGATGGCATCGACGTCGCCCAAGCCTGGAAAACAACGCAGGGCGA
AGGCGTGGTGGTGGCGGTACTGGATACCGGCGTCCTGCCCGACCACCCAGACTTGGCCGGCAATCTGCTCACCGGCTACG
ACTTCATCACCGACCCGTTCTTCTCGCGTCGCGCCACGGCCGAGCGTGTGCCCGGCGCACTGGACCTCGGCGATTGGATC
GTCGAAGACGGCGATTGCGGGCTGTTCTCGGTGGCCAGCGACAGCAGCTGGCACGGCACGCACGTGGCCGGCACGGTTGC
CGAAGCCACCAACAACGGCATTGGCGGGGCAGGCGTCGCCTACCGGGCGAAAGTGCTGCCGGTGCGCGTGCTCGGGCACT
GCGGCGGGCGACTCTCCGACATCTCCGATGCCATCGTCTGGGCGTCCGGCGGTCACGTCGATGGCGTACCGGACAACCGC
GATCCGGCCGAAGTGATCAACCTAAGCCTGGGCGGTGGCGGTGCATGCGGTTCGGCGATGCAGGCCGCGATCGATGGCGC
AGTGGCGCGCGGCACCACCGTGGTGGTGGCGGCGGGTAATTCAACGGCCGATGTATCGACGACGACTCCCGCCAACTGCG
CCAATGTGATTGCCGTTGCCGCCACGCGCGCAACCGGCGCGCTTGCCGATTACAGCAATTTCGGCCGTCAGATCGACCTG
GCCGGCCCGGGCGGCAGCTCGATGTCCTTCATCACCAACGATGGCCCGATCCGCAGCTTTGTTTGGCAAACCCTCTACAC
CGGCAAAACCACACCAACCTCCGGGCAGTTCACCTATGGCGGCACGCGTTACGCCGGCACCTCGATGGCGTCGCCGCATG
TGGCCGGCACCGCCGCATTGGTGCAGAGCGCATTGATCGCCGACGGCAAACCGCCGTTGTCGCCGGCCGCAATGGAGAGC
CTGCTCAAGCGCACTGCGCGCGCATTCCCGGTGTCGATTCCGGTGGCAACGCCGGCCGGGGCAGGCATCGTGGATGCCGG
AGCCGCAGTTGCGCGCGCGTTACGTCGCTGCGATAGGGGCGATGTGGGATGTCAGGTGGATGCGCAGCCTCTGCGTAATG
GCGTGGTGCAGAGCGGCATCTCCAATCTGTCGGGCGATGCGGGGGTGTTCACGTTCCAAGCGCAGGCGGGTGCGGTGCTG
AGTTTCATCAGCTTCGGCGGCAGCGGCCAGGCGGGGTTGTACGTGGCATTCGGGCGCGAGCCCACCGCCACCGACAACGA
CGGCGCGTCTACGCGTCGCGGCACCAGCCAGACGGTGCGCTTCACTGCGCCGCGTGCCGGCACCTACATTCTCAAGCTGG
AAGGCAGCGGTTTCGACGCGGTGAGCCTGCTGGCGCGCCAATGA

Upstream 100 bases:

>100_bases
GCAGCACGGCCACGCGGTCGCATGCATTCCCGCCGCCCGTCGCCGGGCGGCGCGCTTTCTTCGTCATGCCCTTTCGCACT
CACCTCGAAGGAATCCCATC

Downstream 100 bases:

>100_bases
TCCGACATGTCGCCGCCGGTTCGGCGAAATCGTCATTTCCTTGGCGGTGAACGCCTGAAACACGGCCACCTCGCGCGCCG
ATCGACCGCGCATGCTGGCT

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MIQSSSTQVLVLACCVLAASCSTALAANPNANADAAAANAQRQQAMANAPVDRIIVRYRSGQVGTARDIGRSASAAVSAA
ASRASVRLAPAARTSATAAPTYLRTLAAGGELIKLPAQLSRADADRLVQELSADPAVESAQVDLRMYPLQTSGALPNDPL
LQTNQWHLIDPVDGIDVAQAWKTTQGEGVVVAVLDTGVLPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWI
VEDGDCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGRLSDISDAIVWASGGHVDGVPDNR
DPAEVINLSLGGGGACGSAMQAAIDGAVARGTTVVVAAGNSTADVSTTTPANCANVIAVAATRATGALADYSNFGRQIDL
AGPGGSSMSFITNDGPIRSFVWQTLYTGKTTPTSGQFTYGGTRYAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMES
LLKRTARAFPVSIPVATPAGAGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLSGDAGVFTFQAQAGAVL
SFISFGGSGQAGLYVAFGREPTATDNDGASTRRGTSQTVRFTAPRAGTYILKLEGSGFDAVSLLARQ

Sequences:

>Translated_627_residues
MIQSSSTQVLVLACCVLAASCSTALAANPNANADAAAANAQRQQAMANAPVDRIIVRYRSGQVGTARDIGRSASAAVSAA
ASRASVRLAPAARTSATAAPTYLRTLAAGGELIKLPAQLSRADADRLVQELSADPAVESAQVDLRMYPLQTSGALPNDPL
LQTNQWHLIDPVDGIDVAQAWKTTQGEGVVVAVLDTGVLPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWI
VEDGDCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGRLSDISDAIVWASGGHVDGVPDNR
DPAEVINLSLGGGGACGSAMQAAIDGAVARGTTVVVAAGNSTADVSTTTPANCANVIAVAATRATGALADYSNFGRQIDL
AGPGGSSMSFITNDGPIRSFVWQTLYTGKTTPTSGQFTYGGTRYAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMES
LLKRTARAFPVSIPVATPAGAGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLSGDAGVFTFQAQAGAVL
SFISFGGSGQAGLYVAFGREPTATDNDGASTRRGTSQTVRFTAPRAGTYILKLEGSGFDAVSLLARQ
>Mature_627_residues
MIQSSSTQVLVLACCVLAASCSTALAANPNANADAAAANAQRQQAMANAPVDRIIVRYRSGQVGTARDIGRSASAAVSAA
ASRASVRLAPAARTSATAAPTYLRTLAAGGELIKLPAQLSRADADRLVQELSADPAVESAQVDLRMYPLQTSGALPNDPL
LQTNQWHLIDPVDGIDVAQAWKTTQGEGVVVAVLDTGVLPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWI
VEDGDCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGRLSDISDAIVWASGGHVDGVPDNR
DPAEVINLSLGGGGACGSAMQAAIDGAVARGTTVVVAAGNSTADVSTTTPANCANVIAVAATRATGALADYSNFGRQIDL
AGPGGSSMSFITNDGPIRSFVWQTLYTGKTTPTSGQFTYGGTRYAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMES
LLKRTARAFPVSIPVATPAGAGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLSGDAGVFTFQAQAGAVL
SFISFGGSGQAGLYVAFGREPTATDNDGASTRRGTSQTVRFTAPRAGTYILKLEGSGFDAVSLLARQ

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324576, Length=379, Percent_Identity=27.1767810026385, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320775, Length=325, Percent_Identity=28.6153846153846, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319893, Length=306, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 63677; Mature: 63677

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQSSSTQVLVLACCVLAASCSTALAANPNANADAAAANAQRQQAMANAPVDRIIVRYRS
CCCCCCCHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECC
GQVGTARDIGRSASAAVSAAASRASVRLAPAARTSATAAPTYLRTLAAGGELIKLPAQLS
CCCCCHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCHHHH
RADADRLVQELSADPAVESAQVDLRMYPLQTSGALPNDPLLQTNQWHLIDPVDGIDVAQA
HCHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHH
WKTTQGEGVVVAVLDTGVLPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWI
HCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCHHHCCCHHHHCCHHHHCCCCCCCCCEE
VEDGDCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGRLSD
EECCCCCEEEECCCCCCCCCEEEEEHHHHCCCCCCCCCCEEEEEEEEEHHHHHCCCCHHC
ISDAIVWASGGHVDGVPDNRDPAEVINLSLGGGGACGSAMQAAIDGAVARGTTVVVAAGN
CCCEEEEECCCCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
STADVSTTTPANCANVIAVAATRATGALADYSNFGRQIDLAGPGGSSMSFITNDGPIRSF
CCCCCCCCCCCCHHHEEEEEEHHCCCCHHHHHHCCCEEEECCCCCCCCEEEECCCCHHHH
VWQTLYTGKTTPTSGQFTYGGTRYAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMES
HHHHHHCCCCCCCCCEEECCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
LLKRTARAFPVSIPVATPAGAGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGI
HHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHH
SNLSGDAGVFTFQAQAGAVLSFISFGGSGQAGLYVAFGREPTATDNDGASTRRGTSQTVR
HHCCCCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
FTAPRAGTYILKLEGSGFDAVSLLARQ
EECCCCCEEEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MIQSSSTQVLVLACCVLAASCSTALAANPNANADAAAANAQRQQAMANAPVDRIIVRYRS
CCCCCCCHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECC
GQVGTARDIGRSASAAVSAAASRASVRLAPAARTSATAAPTYLRTLAAGGELIKLPAQLS
CCCCCHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCHHHH
RADADRLVQELSADPAVESAQVDLRMYPLQTSGALPNDPLLQTNQWHLIDPVDGIDVAQA
HCHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHH
WKTTQGEGVVVAVLDTGVLPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWI
HCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCHHHCCCHHHHCCHHHHCCCCCCCCCEE
VEDGDCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGRLSD
EECCCCCEEEECCCCCCCCCEEEEEHHHHCCCCCCCCCCEEEEEEEEEHHHHHCCCCHHC
ISDAIVWASGGHVDGVPDNRDPAEVINLSLGGGGACGSAMQAAIDGAVARGTTVVVAAGN
CCCEEEEECCCCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
STADVSTTTPANCANVIAVAATRATGALADYSNFGRQIDLAGPGGSSMSFITNDGPIRSF
CCCCCCCCCCCCHHHEEEEEEHHCCCCHHHHHHCCCEEEECCCCCCCCEEEECCCCHHHH
VWQTLYTGKTTPTSGQFTYGGTRYAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMES
HHHHHHCCCCCCCCCEEECCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
LLKRTARAFPVSIPVATPAGAGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGI
HHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHH
SNLSGDAGVFTFQAQAGAVLSFISFGGSGQAGLYVAFGREPTATDNDGASTRRGTSQTVR
HHCCCCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
FTAPRAGTYILKLEGSGFDAVSLLARQ
EECCCCCEEEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]