Click here to switch to the map view.

The map label for this gene is 78049225

Identifier: 78049225

GI number: 78049225

Start: 4224496

End: 4226379

Strand: Reverse

Name: 78049225

Synonym: XCV3669

Alternate gene names: NA

Gene position: 4226379-4224496 (Counterclockwise)

Preceding gene: 78049226

Following gene: 78049224

Centisome position: 81.61

GC content: 67.83

Gene sequence:

>1884_bases
GTGATCGACAAGAATTTCCGTCTCAACCCGCTGACCGGCGCCATCCTGATGATGGCCCTCGGTGCCTCTGGCACGCTCGC
TGCCGCCCCCAAACTGCTGGTCAAGGAACCGACCCAGGCAGCCCCGGCCGGCGCAGCGTTCGGTAGCCGGTTGATCGTGC
GCTACAAGGACAATACCGCCGCTGCAACCGATCGCAGCAGCAAGCTGAGCGCCGTGCAGGCCGCGGTGGGCCGCGTTGGC
GCCAGTACCGGCGCGCGCAGCAGCGCTGCCGCCGCCAAGGCGACGTATGTGCGCAAGCTGGGCATCGGCTCGGACCTGAT
CAAGCTGTCCAGCACGCTGACCGCCGCGCAGGTGGACAAGGTGGTGGTCGAGCTCAAGAACGACCCATCCGTGGCCGACG
TGCAGATCGACCGCATGCTGCGCCCGATCGATATCAGCAAAAGCCTGCCTGCCACCGACGTGAGCCCGCAGCTGGTTCCC
AACGACCCGTTCTACGCCCAGTACCAGTGGCACCTGAGCAACCCCAACGGCGGCATCAACGCACCGGGCGCCTGGGATCT
GTCGCAGGGCGCAGGCGTGGTGGTGGCGGTGCTGGATACCGGCATCCTGCCGGATCACCCCGATTTTGCCGGCAATCTCC
TGCAGGGCTACGACTTCATCACCGACGCCGAAGTCTCGCGTCGTCCCACCGATGCGCGCGTGCCGGGCGCACTCGATTAC
GGCGACTGGGAAGAGGCCGACAACGTTTGCTACGCGGGCTCGCAGGCGCAGGAAAGTTCCTGGCACGGCACCCACGTTTC
AGGCACCGTGGCCGAGGCGACCAATAACGGCGTGGGCATGGCGGGCGTCGCGCCGAAGGCGACCATCCTGCCGGTGCGCG
TGCTCGGCCGTTGCGGCGGCTACACCTCCGACATCGCCGATGCGATCGTGTGGGCCTCCGGCGGCAGCGTCGACGGCGTG
CCGGCCAACACCAATCCGGCCGAAGTGATCAACATGAGCCTCGGGGGCGGCGAGCCCTGCGATTCGGCCACCCAGCTGGC
GATCAATGGCGCGGTGTCGCGCGGCACCACCGTGGTGGTCGCGGCCGGCAACAGCAGCGAAGATGCGGCCAACCATTCGC
CGGCCAGCTGCAACAACACCATCACCGTTGGCGCCACGCGCATCACCGGTGGCATCGCCTACTACTCCAACAACGGCAGC
AAGGTCGACCTCTCTGGTCCGGGCGGCGGCGGTAGCGTGGACGGCAATCCGGGCGGTTACGTCTGGCAGGCCGGGTACAC
CGGTGCGACCACGCCGACCTCCGGTAGCTATACCTATATGGGTCTAGGCGGCACCTCGATGGCCTCGCCGCACGTGGCCG
GCGTCGTGGCGCTGGTGCAGAGCGCAGCCATCGGTCTGGGCGATGGCCCGCTGACCCCGGCTGCGGTCGAAGCCCTGCTC
AAGCAGACCAGCCGCCCCTTCCCGGTGACTCCGCCGGCCAGCACCCCGATCGGCAGCGGTATCGTCGACGCCAAGGCCGC
GCTGGAAGCCGTGCTGGAGGAGCCGTGCGACCCGGCCACCGAGAGCTGCGCGCCGAGCGCCATTGCGCTCACCAACAAGG
CGCCTGTTGCTGGATTGAGCGGTACCGCCGGCAGCTCCACGCTGTACAGCTTCGAGGCCAAGGCCGGCGCCGTGCTCAGC
TTCATGACCTACGGCGGCACCGGCGATGTGTCGATGTACGTCAGCTTCGAGGCCGAGCCCAGCGCCACAAGCTACGACGC
CAAGTCGACCCGTCCGGGCAACAGCGAAACCGTGCGTTTCACTGCCCCCAAGGCCGGCACCTACTACATCAAGTTGGTCG
GCGCGGCGAGCTACGCGAAGCTGACGCTCGTTGCACGACAGTAA

Upstream 100 bases:

>100_bases
GGGTGGCCGACAAGGACGCAGCGCACCGCACCGCGGCTACGCAGCGATTGCGCCGGCTGCGCCAAGCCTGATTCACGAAA
AATACGAAGAGGACTTCACC

Downstream 100 bases:

>100_bases
GTAGCGAAATAGTGTGACCGATGCCCCCGGCCAATCGCCGGGGGCATTGTTTTTCAGGGCGTTTCAAATGCGTGCGGTTG
ATCGTCGCGGCAAACTGCTA

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDNTAAATDRSSKLSAVQAAVGRVG
ASTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDKVVVELKNDPSVADVQIDRMLRPIDISKSLPATDVSPQLVP
NDPFYAQYQWHLSNPNGGINAPGAWDLSQGAGVVVAVLDTGILPDHPDFAGNLLQGYDFITDAEVSRRPTDARVPGALDY
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGGYTSDIADAIVWASGGSVDGV
PANTNPAEVINMSLGGGEPCDSATQLAINGAVSRGTTVVVAAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNNGS
KVDLSGPGGGGSVDGNPGGYVWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
KQTSRPFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIALTNKAPVAGLSGTAGSSTLYSFEAKAGAVLS
FMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRFTAPKAGTYYIKLVGAASYAKLTLVARQ

Sequences:

>Translated_627_residues
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDNTAAATDRSSKLSAVQAAVGRVG
ASTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDKVVVELKNDPSVADVQIDRMLRPIDISKSLPATDVSPQLVP
NDPFYAQYQWHLSNPNGGINAPGAWDLSQGAGVVVAVLDTGILPDHPDFAGNLLQGYDFITDAEVSRRPTDARVPGALDY
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGGYTSDIADAIVWASGGSVDGV
PANTNPAEVINMSLGGGEPCDSATQLAINGAVSRGTTVVVAAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNNGS
KVDLSGPGGGGSVDGNPGGYVWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
KQTSRPFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIALTNKAPVAGLSGTAGSSTLYSFEAKAGAVLS
FMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRFTAPKAGTYYIKLVGAASYAKLTLVARQ
>Mature_627_residues
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDNTAAATDRSSKLSAVQAAVGRVG
ASTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDKVVVELKNDPSVADVQIDRMLRPIDISKSLPATDVSPQLVP
NDPFYAQYQWHLSNPNGGINAPGAWDLSQGAGVVVAVLDTGILPDHPDFAGNLLQGYDFITDAEVSRRPTDARVPGALDY
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGGYTSDIADAIVWASGGSVDGV
PANTNPAEVINMSLGGGEPCDSATQLAINGAVSRGTTVVVAAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNNGS
KVDLSGPGGGGSVDGNPGGYVWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
KQTSRPFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIALTNKAPVAGLSGTAGSSTLYSFEAKAGAVLS
FMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRFTAPKAGTYYIKLVGAASYAKLTLVARQ

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=323, Percent_Identity=30.030959752322, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324576, Length=389, Percent_Identity=26.9922879177378, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319893, Length=282, Percent_Identity=29.0780141843972, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 63382; Mature: 63382

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDNTA
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCHHEECCCCCCCCCCCCCCCEEEEEECCCCC
AATDRSSKLSAVQAAVGRVGASTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDK
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCE
VVVELKNDPSVADVQIDRMLRPIDISKSLPATDVSPQLVPNDPFYAQYQWHLSNPNGGIN
EEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
APGAWDLSQGAGVVVAVLDTGILPDHPDFAGNLLQGYDFITDAEVSRRPTDARVPGALDY
CCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEECCHHHCCCCCCCCCCCCCC
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGG
CCCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCEEEHHHHHHHCCC
YTSDIADAIVWASGGSVDGVPANTNPAEVINMSLGGGEPCDSATQLAINGAVSRGTTVVV
CHHHHHHHEEEECCCCCCCCCCCCCHHHEEEEECCCCCCCCCHHEEEEECCCCCCCEEEE
AAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNNGSKVDLSGPGGGGSVDGNPGGY
ECCCCCCCCCCCCCCCCCCEEEEEEEEEECEEEEEECCCCEEEECCCCCCCCCCCCCCCE
VWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
EEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KQTSRPFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIALTNKAPVAGLS
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCCCCCCC
GTAGSSTLYSFEAKAGAVLSFMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRF
CCCCCCEEEEECCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEE
TAPKAGTYYIKLVGAASYAKLTLVARQ
ECCCCCEEEEEEEECCCEEEEEEEECC
>Mature Secondary Structure
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDNTA
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCHHEECCCCCCCCCCCCCCCEEEEEECCCCC
AATDRSSKLSAVQAAVGRVGASTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDK
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCE
VVVELKNDPSVADVQIDRMLRPIDISKSLPATDVSPQLVPNDPFYAQYQWHLSNPNGGIN
EEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
APGAWDLSQGAGVVVAVLDTGILPDHPDFAGNLLQGYDFITDAEVSRRPTDARVPGALDY
CCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEECCHHHCCCCCCCCCCCCCC
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGG
CCCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCEEEHHHHHHHCCC
YTSDIADAIVWASGGSVDGVPANTNPAEVINMSLGGGEPCDSATQLAINGAVSRGTTVVV
CHHHHHHHEEEECCCCCCCCCCCCCHHHEEEEECCCCCCCCCHHEEEEECCCCCCCEEEE
AAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNNGSKVDLSGPGGGGSVDGNPGGY
ECCCCCCCCCCCCCCCCCCEEEEEEEEEECEEEEEECCCCEEEECCCCCCCCCCCCCCCE
VWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
EEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KQTSRPFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIALTNKAPVAGLS
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCCCCCCC
GTAGSSTLYSFEAKAGAVLSFMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRF
CCCCCCEEEEECCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEE
TAPKAGTYYIKLVGAASYAKLTLVARQ
ECCCCCEEEEEEEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]