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The map label for this gene is ybhD [H]

Identifier: 78049160

GI number: 78049160

Start: 4145565

End: 4146467

Strand: Reverse

Name: ybhD [H]

Synonym: XCV3604

Alternate gene names: 78049160

Gene position: 4146467-4145565 (Counterclockwise)

Preceding gene: 78049164

Following gene: 78049155

Centisome position: 80.07

GC content: 65.23

Gene sequence:

>903_bases
GTGACCATCAAATTCGACCTCAACGATCTGCAGGCATTCCGTGCGGTTGCCGAAAACGGCAGCTTTCGCCGCGCTGCCGA
ACGCATCCGCATCACGCAACCGGCACTCAGCCGCAGGATCGACAAGCTCGAGTCGGCGTTGAACGTCAAACTGTTCGAGC
GCACCACGCGCAAGGTCACGCTCACCACCGTCGGCCAGGCGTTCATGCCGCAGGTCGAGCGCATGCTCGACGATCTGGAC
ATGGCGCTGATGAGCATCGGCGATGCAGGGTCCAGCAGGATGGGCACGGTGACCGTGGCCTGCGTGCCGTCTGCGGCGTA
CTACTTCATGCCGCAGGCGATCCACGGGCTGCATCAGTTGTTTCCCAAGATCCGCATCCGGCTGTTCGACGGCAGCGCCA
GTCATGTCAGTGCGGCAGTGGCCTCCGGCGAAGCGGATTTCGGGGTCAGCTTCAGCGGCAACCTGGCGCCGGAGGTGGAG
TTCGAACCGTTGTTGCAGGAGCGCTATGTGATTGCCTGCCGCCAGGACCATCCGCTGTCCGGGCGCGCACAGGTCAGCTG
GCAGGAGGCCTACGGTTACGACTACATCACGCTGGACAAGACATCGGGCAACCGGCTGGTGCTGGATCGGGCGCTGGCTG
CATTCACGCCGGACAAGCCGAGCATCTGCGAGACCCGGCATGTCACCACGTTGCTGGGGTTGGTGGAGGCCGGCGTCGGT
ATTGCCGCCGTGCCGTCGATTGCCATGCCGTCCGGCCCGCATCCGGTGCTGGCGGCGGTGCCGCTGGTCGAACCGGAGGT
GTCGCGCAACGTGGGGCTGCTGAAACGTCGCGGACGCACGCTGACACCGACCGCGCTGGAACTGGCGGAACTGGTGCGAC
GGATGCCCGCACGTTCAGGGTGA

Upstream 100 bases:

>100_bases
ACTGCGCCCGAATGCAGTGGCTCTCTTGGCGTCAGACGCAGCACCGCAGGCAAGCGTCTATGCTATGGCGACCGCCATCG
AACACTGAAGCCGTGGCACC

Downstream 100 bases:

>100_bases
CACCGGGTCCAGGCCGGTCGCGCGCGCCACCGCCTGCGCATTACCCGACTGCAGGTACGCAAGCAGGCGCTTGGCCGCCT
CGGGATGCTCCGCGTTGACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVTLTTVGQAFMPQVERMLDDLD
MALMSIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQLFPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVE
FEPLLQERYVIACRQDHPLSGRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSG

Sequences:

>Translated_300_residues
MTIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVTLTTVGQAFMPQVERMLDDLD
MALMSIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQLFPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVE
FEPLLQERYVIACRQDHPLSGRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSG
>Mature_299_residues
TIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVTLTTVGQAFMPQVERMLDDLDM
ALMSIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQLFPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVEF
EPLLQERYVIACRQDHPLSGRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVGI
AAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=42.1602787456446, Blast_Score=262, Evalue=2e-71,
Organism=Escherichia coli, GI1788748, Length=291, Percent_Identity=32.9896907216495, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=30.6122448979592, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI157672245, Length=273, Percent_Identity=28.5714285714286, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787601, Length=302, Percent_Identity=27.8145695364238, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789204, Length=239, Percent_Identity=25.1046025104602, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=27.4590163934426, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081904, Length=178, Percent_Identity=30.3370786516854, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787530, Length=259, Percent_Identity=24.7104247104247, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790208, Length=266, Percent_Identity=26.6917293233083, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=26.2948207171315, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=26.9709543568465, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787589, Length=154, Percent_Identity=32.4675324675325, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789506, Length=177, Percent_Identity=25.9887005649718, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786713, Length=192, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788296, Length=213, Percent_Identity=24.4131455399061, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082132, Length=153, Percent_Identity=30.718954248366, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787128, Length=126, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789173, Length=147, Percent_Identity=31.2925170068027, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=249, Percent_Identity=21.285140562249, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788481, Length=242, Percent_Identity=23.9669421487603, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788706, Length=169, Percent_Identity=26.0355029585799, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=150, Percent_Identity=30.6666666666667, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786401, Length=122, Percent_Identity=31.9672131147541, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786508, Length=184, Percent_Identity=26.6304347826087, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32717; Mature: 32586

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVT
CEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCEEE
LTTVGQAFMPQVERMLDDLDMALMSIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQL
EEHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHH
FPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVEFEPLLQERYVIACRQDHPLS
HHHHEEEEECCCCHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHCCEEEEECCCCCCC
GRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
CCEEEEEHHHCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSG
CEECCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVT
EEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCEEE
LTTVGQAFMPQVERMLDDLDMALMSIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQL
EEHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHH
FPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVEFEPLLQERYVIACRQDHPLS
HHHHEEEEECCCCHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHCCEEEEECCCCCCC
GRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
CCEEEEEHHHCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSG
CEECCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]