Click here to switch to the map view.

The map label for this gene is waaA [H]

Identifier: 78049148

GI number: 78049148

Start: 4125503

End: 4126819

Strand: Reverse

Name: waaA [H]

Synonym: XCV3592

Alternate gene names: 78049148

Gene position: 4126819-4125503 (Counterclockwise)

Preceding gene: 78049150

Following gene: 78049144

Centisome position: 79.69

GC content: 66.29

Gene sequence:

>1317_bases
ATGCGGAAAGATCCGATCGAATGGCTGTTGCGCGGGCTGTACTCGGCGCTGCTCTACCTGTTGTTGCCGGTCACGGTGTA
CCACCTGGTGTGGCGCGGTTTCCGCGTGCGCGAATACTTCAATCGCTGGAACGAGCGCTATGCGTCCTACACGCACGCCT
GCGGGCGCCCGCGGGTGTGGGTGCATGCGGTGTCGGTGGGCGAGGTCAACGCGTCCGCGCCGCTGGTCAATGCGCTACGA
GCGCAGCGCCCGGATATCCGTTGGGTCATCACCACCATCACCCCCACCGGCTCCGAGCGCGTGCGCGCGCTGTGGGGCGA
TGCGGTGGACCATGTGTATCTGCCCTACGACGTGCCGGGCAGCGTGGGGCGGTTTCTCGAACACTTCCGCCCGCGCCTGG
CCTTGATCCTGGAAACCGAGCTGTGGCCAAACATGTTGTTCGGCTGCCGCGATCGCCAGATTCCGGTGTACATCCTCAAC
GCACGGTTGTCGGCGCGCTCGTTGCGCGGCTATCGGTTGCTGGCGCCGTTGATCAGTCGTGCGCTGCGTACCGTCACCTG
CGTGGCGGCGCAGTCGCAGGACGATGCCGAGCGGTTCGTCACCCTGGGCGCGCGCCCGAATCAGGTGATCGCGCTGGGCA
ATCTCAAGTTCGATATCGCCGCGCCAACGCAATTGCAGGCGTTGGTCGCGCAGTTTCGCACGCACGTGCCAGCCACGCGC
CCAGTGTGGATCGCCGCCAGTACGCACGAAGGCGAAGAGGCCGCCGTTGCCGATATCCACGCACGGTTGCTGCTGCAATT
TCCGGATTTGCTGCTGTTGTGGGCACCGCGCCATCCCGAGCGCTTTCCCAAGGTCGAGACGTTGGCACGCGAGCGCGGCT
GGCGCGTTGCCACGCGCAAGGCGCAGCAATGGCCGCAGGCGGGCGACAAGGTATTCGTCATCGACACCCTGGGCGAGCTG
ATGAGCTTCTATGCGTGCGCGCAGGTGGCTTTCGTCGGTGGCAGTCTGCAACCGATCGGCGGGCATAACCTGCTTGAGCC
GGCCGCCGTCGGAACGCCGGCAATCACTGGCCCGCATCTGCATAACTTCTCGGAGATTTCGCGGCGCATGCGCCAAGCCG
ATGCGGTTGCCATCTGCGAGGATGCCGAGTGCGTCTACCAGGCATTGGCGCGCCTGCTCGCCGACCCCGCACAACGCGAG
GCGATGACCACTGCAGGCCTGGCGCTGGTCGCCAACGGCAAGGGCGCGGTGGCCCGCACCTTGGTGCAGATCGCTGCCGA
TCTGCCGCCGCTGGCGAGCGCGGGCGTTGTGGCATGA

Upstream 100 bases:

>100_bases
GCTTCGCACTCACCTCAACGTACATACCACGCTCTAAGGGATTGCGCCCAGCAGGCAGCGTGCACATGCGCACGCACGGA
CGCTCCCGTATCCTGCACGG

Downstream 100 bases:

>100_bases
GGTTTGTCGCTCGCTGCGTGGCTGCGTGGCTGCGTGCATGGGCGTGCCGCACTCCGCCGAGCCTGGCGCCGGAGTGCAGC
CCTCGTTGCGCTCAACCGTG

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVWVHAVSVGEVNASAPLVNALR
AQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPGSVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILN
ARLSARSLRGYRLLAPLISRALRTVTCVAAQSQDDAERFVTLGARPNQVIALGNLKFDIAAPTQLQALVAQFRTHVPATR
PVWIAASTHEGEEAAVADIHARLLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRKAQQWPQAGDKVFVIDTLGEL
MSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHLHNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQRE
AMTTAGLALVANGKGAVARTLVQIAADLPPLASAGVVA

Sequences:

>Translated_438_residues
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVWVHAVSVGEVNASAPLVNALR
AQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPGSVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILN
ARLSARSLRGYRLLAPLISRALRTVTCVAAQSQDDAERFVTLGARPNQVIALGNLKFDIAAPTQLQALVAQFRTHVPATR
PVWIAASTHEGEEAAVADIHARLLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRKAQQWPQAGDKVFVIDTLGEL
MSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHLHNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQRE
AMTTAGLALVANGKGAVARTLVQIAADLPPLASAGVVA
>Mature_438_residues
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVWVHAVSVGEVNASAPLVNALR
AQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPGSVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILN
ARLSARSLRGYRLLAPLISRALRTVTCVAAQSQDDAERFVTLGARPNQVIALGNLKFDIAAPTQLQALVAQFRTHVPATR
PVWIAASTHEGEEAAVADIHARLLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRKAQQWPQAGDKVFVIDTLGEL
MSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHLHNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQRE
AMTTAGLALVANGKGAVARTLVQIAADLPPLASAGVVA

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=422, Percent_Identity=46.4454976303318, Blast_Score=370, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 48621; Mature: 48621

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
VHAVSVGEVNASAPLVNALRAQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPG
EEEEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEECCCCCC
SVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILNARLSARSLRGYRLLAPLISR
HHHHHHHHHCCCEEEEEECHHCHHHHHCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHH
ALRTVTCVAAQSQDDAERFVTLGARPNQVIALGNLKFDIAAPTQLQALVAQFRTHVPATR
HHHHHHHHHCCCCCCHHHHEEECCCCCCEEEEECEEEEECCCHHHHHHHHHHHHCCCCCC
PVWIAASTHEGEEAAVADIHARLLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRK
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHH
AQQWPQAGDKVFVIDTLGELMSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHL
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQREAMTTAGLALVANGKGAVART
CCHHHHHHHHHHHCHHEEECCHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCHHHHH
LVQIAADLPPLASAGVVA
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
VHAVSVGEVNASAPLVNALRAQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPG
EEEEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEECCCCCC
SVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILNARLSARSLRGYRLLAPLISR
HHHHHHHHHCCCEEEEEECHHCHHHHHCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHH
ALRTVTCVAAQSQDDAERFVTLGARPNQVIALGNLKFDIAAPTQLQALVAQFRTHVPATR
HHHHHHHHHCCCCCCHHHHEEECCCCCCEEEEECEEEEECCCHHHHHHHHHHHHCCCCCC
PVWIAASTHEGEEAAVADIHARLLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRK
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHH
AQQWPQAGDKVFVIDTLGELMSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHL
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQREAMTTAGLALVANGKGAVART
CCHHHHHHHHHHHCHHEEECCHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCHHHHH
LVQIAADLPPLASAGVVA
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]