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The map label for this gene is pilQ [H]

Identifier: 78049053

GI number: 78049053

Start: 4008015

End: 4009964

Strand: Reverse

Name: pilQ [H]

Synonym: XCV3497

Alternate gene names: 78049053

Gene position: 4009964-4008015 (Counterclockwise)

Preceding gene: 78049054

Following gene: 78049052

Centisome position: 77.44

GC content: 59.9

Gene sequence:

>1950_bases
ATGACGTTTTCCAATGCCCAGCGGCTGCGTCCGGTACGACGCCACGCGATCTTCCAGGCCTGCGCGTTGGGGTTCGCGCT
GGCGCTGGCGAGCGGCAGCGCGTTCGCCGCCGCGGCGCTGACTCAGCCCGCGCAGGATCCGGCCAAGGTCGCTCCGGCGA
GCCTGGCGGTGTCCAAAATCGATTTCAAGCGCGGCGAAGACGGCGCTGGCCGTCTGATCCTGCAGTTCGACGGCCAGGGC
GCCAGCCCGGACCTGCGGACGCAAGGCGACAACGTGCTGGTGGACATCAGCAATGCCAAGCTACCCGCCGAGCTGCAACG
CCCGCTCAATGTCACCGACTTCGCCACGCCGGTGCAGCGCGTTGAAGTGAAGCCGTCCGGCTCCGGTTCGCAGCTGGTGC
TGTCGACCAAGGGTGCCTTCGACTCGCTGGCCTACCAGACCGGCAACGAATACGTGGTGGAAATCACCCCGCGCAAGGGC
CAGCCGGCGGTTGGCGGTGTGAGCCCGGCGGCGGTCACGCAGGCTGCCGCGCAGATCGCTGCGCGCGGCTACAGCGGCCG
CCCGGTGACGTTCAACTTCCAGGACGTGCCGGTGCGCACCGTGCTGCAGCTGATCGCCGAGGAGTCCAACCTCAATATCG
TCGCTTCCGACACCGTGCAGGGCAACGTCACGCTGCGCCTGATGAACGTGCCGTGGGACCAGGCGCTGGACATCGTGCTG
CGTGCCAAGGGCCTGGACAAGCGCCGCGATGGTGGCGTGGTTTGGGTCGCCCCGCAACCGGAGCTGGCCAAGTTCGAGCA
GGACAAGGAAGACGCCCGCATCGCGATCGAGAACCGTGAGGACTTGATCACCGATTATGTGCAGATCAATTACCACAACG
CTGCGGTGATCTTCAAAGCGCTGACGGAGGCCAAGGGGATTGGTGGCGGTGGTGGCGGCCAGGGCGGCCAGGGCGGACAA
GGTGGTGCGGGGCAGCAGGACAATGGTTTCCTTTCGCCACGTGGTCGGTTGGTTGCCGATGAACGCACCAACACATTGAT
GATCAGCGATATTCCGAAGAAGGTCGCGCAAATGCGCGAGCTGATTTCGCATATTGACCGCCCAGTGGATCAGGTGCTGA
TCGAGAGCCGGATTGTCATTGCGACGGATACTTTTGCGCGTGATTTGGGTGCGCGGTTCGGCATCACTGGCGCAACCGGA
CGTGGGATTTTGAGCGGGGCGCTGGAGAGTAACGTCAACTTCCAGAACACTTCAGCGCAACGAGCTAATGAAATCGCTAA
TACTGGTACCAGTACAACGCTGGCTTCGCATTTGTTCCCTTCGGGGTTGAATGTCGATTTGGGGGCTAGTGGCTTTACCA
ATAGCAGAGCGGCCGGCTTGGCGTATACCTTGCTTGGATCCAATTTCAACCTCGACATTGAGCTATCGGCAATGCAAGAG
GAAGGGCGAGGTGAGGTCGTCTCAAATCCGCGGATCGTGACGGCCAATCAGCGTGAGGGTGTCATCAAGCAAGGTCGGGA
GATTGGGTATGTGACAATCAGTGGTGGTGGTGCGGCAGGTTCCGCCGCGCAGGCGAATGTGCAGTTCAAGGAAGTTCTAC
TTGAATTGAAGGTTACGCCCACCATCACGAATGACAATCGCGTCTTCTTGAATATGAATGTCAAGAAGGACGAGGTGGCT
CGATTCATTATTTTGGAAGGCTACGGAACAGTTCCCGAGATTAATCGCCGGGAGGTCAATACTGCTGTGCTAGTAGGCGA
CGGTGAGACAGTAGTCATTGGTGGTGTCTATGAATTTACCGATCGCGAAAGCGTCTCCAAAGTTCCGTTCCTTGGAGATA
TTCCGTTCCTGGGAAATCTCTTCAAGAAGCGCGGACGCAGCAAGGAGAAGGCCGAGCTCCTGGTGTTTGTAACTCCTAAG
GTTCTTCGCGTGGCCAGCGCGAATCCGTAA

Upstream 100 bases:

>100_bases
ATCGAGCTGATTGAACTTGTGCCGGACGGTGCGGGTGGATGGCTTGAACGGCCGGCCGCACTCGCATTGGATGATCAATA
AAGTGATAGGGGATAGCACG

Downstream 100 bases:

>100_bases
TTGAAACTTTTACCGGAAAAGGCCGCGAAAGCGGCCTTTCTCGTATGGATTGCAAATGAGGGGAGTCGCTAGCAGGGTTG
GCCGCGTCTGATATATGCCA

Product: fimbrial assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MTFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKIDFKRGEDGAGRLILQFDGQG
ASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQRVEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKG
QPAVGGVSPAAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGQGGQGGQ
GGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGITGATG
RGILSGALESNVNFQNTSAQRANEIANTGTSTTLASHLFPSGLNVDLGASGFTNSRAAGLAYTLLGSNFNLDIELSAMQE
EGRGEVVSNPRIVTANQREGVIKQGREIGYVTISGGGAAGSAAQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVA
RFIILEGYGTVPEINRREVNTAVLVGDGETVVIGGVYEFTDRESVSKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPK
VLRVASANP

Sequences:

>Translated_649_residues
MTFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKIDFKRGEDGAGRLILQFDGQG
ASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQRVEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKG
QPAVGGVSPAAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGQGGQGGQ
GGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGITGATG
RGILSGALESNVNFQNTSAQRANEIANTGTSTTLASHLFPSGLNVDLGASGFTNSRAAGLAYTLLGSNFNLDIELSAMQE
EGRGEVVSNPRIVTANQREGVIKQGREIGYVTISGGGAAGSAAQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVA
RFIILEGYGTVPEINRREVNTAVLVGDGETVVIGGVYEFTDRESVSKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPK
VLRVASANP
>Mature_648_residues
TFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKIDFKRGEDGAGRLILQFDGQGA
SPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQRVEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQ
PAVGGVSPAAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVLR
AKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGQGGQGGQG
GAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGITGATGR
GILSGALESNVNFQNTSAQRANEIANTGTSTTLASHLFPSGLNVDLGASGFTNSRAAGLAYTLLGSNFNLDIELSAMQEE
GRGEVVSNPRIVTANQREGVIKQGREIGYVTISGGGAAGSAAQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVAR
FIILEGYGTVPEINRREVNTAVLVGDGETVVIGGVYEFTDRESVSKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKV
LRVASANP

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=462, Percent_Identity=28.5714285714286, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI87082242, Length=311, Percent_Identity=28.9389067524116, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 69042; Mature: 68911

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHCCHHHEEEEE
DFKRGEDGAGRLILQFDGQGASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQR
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCCE
VEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQPAVGGVSPAAVTQAAAQIA
EEECCCCCCCEEEEEECCCHHHHHEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
ARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
HCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCEECEEEEEEEECCHHHHHHHHH
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKA
HHCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEECCHHHEEEEEEEEECCHHHHHHH
LTEAKGIGGGGGGQGGQGGQGGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEEHHHHHHHHHHH
LISHIDRPVDQVLIESRIVIATDTFARDLGARFGITGATGRGILSGALESNVNFQNTSAQ
HHHHHCCCHHHHHHHCEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHH
RANEIANTGTSTTLASHLFPSGLNVDLGASGFTNSRAAGLAYTLLGSNFNLDIELSAMQE
HHHHHHCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECC
EGRGEVVSNPRIVTANQREGVIKQGREIGYVTISGGGAAGSAAQANVQFKEVLLELKVTP
CCCCCEECCCEEEECCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHEEEEEEEEE
TITNDNRVFLNMNVKKDEVARFIILEGYGTVPEINRREVNTAVLVGDGETVVIGGVYEFT
EEECCCEEEEEECCCHHHEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEECEEECC
DRESVSKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVASANP
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCHHEEECCCCC
>Mature Secondary Structure 
TFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHCCHHHEEEEE
DFKRGEDGAGRLILQFDGQGASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQR
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCCE
VEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQPAVGGVSPAAVTQAAAQIA
EEECCCCCCCEEEEEECCCHHHHHEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
ARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
HCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCEECEEEEEEEECCHHHHHHHHH
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKA
HHCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEECCHHHEEEEEEEEECCHHHHHHH
LTEAKGIGGGGGGQGGQGGQGGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEEHHHHHHHHHHH
LISHIDRPVDQVLIESRIVIATDTFARDLGARFGITGATGRGILSGALESNVNFQNTSAQ
HHHHHCCCHHHHHHHCEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHH
RANEIANTGTSTTLASHLFPSGLNVDLGASGFTNSRAAGLAYTLLGSNFNLDIELSAMQE
HHHHHHCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECC
EGRGEVVSNPRIVTANQREGVIKQGREIGYVTISGGGAAGSAAQANVQFKEVLLELKVTP
CCCCCEECCCEEEECCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHEEEEEEEEE
TITNDNRVFLNMNVKKDEVARFIILEGYGTVPEINRREVNTAVLVGDGETVVIGGVYEFT
EEECCCEEEEEECCCHHHEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEECEEECC
DRESVSKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVASANP
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]