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The map label for this gene is acrE [C]

Identifier: 78049000

GI number: 78049000

Start: 3943152

End: 3944222

Strand: Reverse

Name: acrE [C]

Synonym: XCV3444

Alternate gene names: 78049000

Gene position: 3944222-3943152 (Counterclockwise)

Preceding gene: 78049001

Following gene: 78048999

Centisome position: 76.17

GC content: 67.88

Gene sequence:

>1071_bases
ATGCCTGTTCTGCCCAGCGCGCGCGTTTGCGCCGCGCTCTTGTTGGCCGCTGTCCTGGCCGGTTGTAGCCGTCAGGCCAG
CACGCCGGCCGCCGCCAAACCCATTCCGGTCTCGGTGCAGACGGTGGCCACCCAACCCTGGAACTCGACCGTGCAGTCGA
TCGCCACCGTGCGTGCGCGCGAATCGGTGGCGCTCACCGCCGCGGTCAGCGATGTGGTGGAGCAGGTGTATTTCGACAGC
GGCGACGAGGTCAAGGCCGGGCAATTGCTGCTGCGTCTGCGCGGCAATTCGCAGCAGGCGGCACTGACCGCCGCACAGGC
CACCTTCGAAGAGACCGACCAGTTGTACCGCCGTCAGTTGAGTCTGGTTGGCCAGCAACTGGTGGCCAAGTCCACCGTGG
ACACGCAGCGCGCGCTGCGCGATGCCGCACAGGCGCGCGTGCAGCAGATGCGCGCGGAAATCACCGACCGCGAAGTGCGC
GCGCCGTTTTCCGGTGTGCTGGGCATCCGCCAGATCAGCCCTGGCTCGCTGATCACCTCCAGCACGGTGATCGCCACGTT
GGACGATGTGGCGCGCATGTACGTGGATTTCCAGGTGCCGGAATCGCAGTTCGGCCTGGTGCAACTCGGTAATGCCGTGA
GCGGCAGCGCGGCGGCGTATCCGGGCGCGCAGTTCCAGGGCGAGGTGGTGACCATCGATTCGCGGATCGATGAGACCACG
CGCTCGGTGACGGTACGTGCGGATTTCCCCAACGACGATCGCCGGCTGCGTCCGGGCATGCTGCTGGATGTGCGGCTGTT
CCAGCCGGCGCGGCAGGCGGTGGTGATTCCGGAAATTGCGGTGGTGCAGGTGGGGCGCGAATCGTACGTCTTCCGGGTCA
AGCCCGACAGCACCGTGGAGCGCGCCGATGTGCGGCTGGGCGAGCGCCGCGACGGCAAGGTGGAAATCCTCGAAGGCATC
AAGGCCGGCGAGCGCATCGTAGTGGACGGCACCGGCAAGCTGCGCCCGGGCCTGAAGATTGCCGATCAGGCCGCGCCCGC
AGCGCCCCGCCCGCAGGCGGCCGCACAATGA

Upstream 100 bases:

>100_bases
GACAGCAAGGGTCTTTGGTCATGGTGCAAAGCGCGCCCTTTCTGTCAATTCATGGCGGCTAGGTCGGTAAACTTTCGACG
TACCCCGCCAGGATGTTCTG

Downstream 100 bases:

>100_bases
AACTCTCCGACCTGTCTATCACCCGCCCGGTGATGGCGGTGGTGATGAGTTTGCTGCTGATCGTGCTGGGGGTGATGTCG
TTCACCCGCCTCACGCTACG

Product: membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MPVLPSARVCAALLLAAVLAGCSRQASTPAAAKPIPVSVQTVATQPWNSTVQSIATVRARESVALTAAVSDVVEQVYFDS
GDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQLSLVGQQLVAKSTVDTQRALRDAAQARVQQMRAEITDREVR
APFSGVLGIRQISPGSLITSSTVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVERADVRLGERRDGKVEILEGI
KAGERIVVDGTGKLRPGLKIADQAAPAAPRPQAAAQ

Sequences:

>Translated_356_residues
MPVLPSARVCAALLLAAVLAGCSRQASTPAAAKPIPVSVQTVATQPWNSTVQSIATVRARESVALTAAVSDVVEQVYFDS
GDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQLSLVGQQLVAKSTVDTQRALRDAAQARVQQMRAEITDREVR
APFSGVLGIRQISPGSLITSSTVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVERADVRLGERRDGKVEILEGI
KAGERIVVDGTGKLRPGLKIADQAAPAAPRPQAAAQ
>Mature_355_residues
PVLPSARVCAALLLAAVLAGCSRQASTPAAAKPIPVSVQTVATQPWNSTVQSIATVRARESVALTAAVSDVVEQVYFDSG
DEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQLSLVGQQLVAKSTVDTQRALRDAAQARVQQMRAEITDREVRA
PFSGVLGIRQISPGSLITSSTVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETTR
SVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVERADVRLGERRDGKVEILEGIK
AGERIVVDGTGKLRPGLKIADQAAPAAPRPQAAAQ

Specific function: May Affect Specific Membrane Functions, Such As Septum Formation During Cell Division, And Cell Membrane Permeability. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=365, Percent_Identity=27.9452054794521, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786668, Length=381, Percent_Identity=27.5590551181102, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87082036, Length=367, Percent_Identity=27.2479564032698, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789929, Length=357, Percent_Identity=25.4901960784314, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38149; Mature: 38018

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLPSARVCAALLLAAVLAGCSRQASTPAAAKPIPVSVQTVATQPWNSTVQSIATVRAR
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
ESVALTAAVSDVVEQVYFDSGDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SLVGQQLVAKSTVDTQRALRDAAQARVQQMRAEITDREVRAPFSGVLGIRQISPGSLITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCEEEECCCCCEEEC
STVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
CHHHHHHHHHHHHHEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVE
CEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCEEEEECCCCCHH
RADVRLGERRDGKVEILEGIKAGERIVVDGTGKLRPGLKIADQAAPAAPRPQAAAQ
HHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCEEHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PVLPSARVCAALLLAAVLAGCSRQASTPAAAKPIPVSVQTVATQPWNSTVQSIATVRAR
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
ESVALTAAVSDVVEQVYFDSGDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SLVGQQLVAKSTVDTQRALRDAAQARVQQMRAEITDREVRAPFSGVLGIRQISPGSLITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCEEEECCCCCEEEC
STVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
CHHHHHHHHHHHHHEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVE
CEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCEEEEECCCCCHH
RADVRLGERRDGKVEILEGIKAGERIVVDGTGKLRPGLKIADQAAPAAPRPQAAAQ
HHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCEEHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]