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The map label for this gene is rimK [H]

Identifier: 78048923

GI number: 78048923

Start: 3854991

End: 3855878

Strand: Reverse

Name: rimK [H]

Synonym: XCV3367

Alternate gene names: 78048923

Gene position: 3855878-3854991 (Counterclockwise)

Preceding gene: 78048925

Following gene: 78048922

Centisome position: 74.46

GC content: 67.0

Gene sequence:

>888_bases
ATGAAAATCGCCATCCTTTCCCGCAACAGCAAGCTGTATTCGACCCGGCGGCTGATCGAAGCCGGACGCAAGCGCGGGCA
CACCGTGCGCATCCTCGACCCGTTGCGCTGCTACATGCGCATCGCCGCCGACGGCTTCAGCCTGCACTACAAGGGCAAGC
CGATCACCGGCTTCGATGCGGTGATCCCGCGCATCGGCGCCTCGGTCACCCGCTATGCCACCGCAGTGCTGCGCCAGCTC
GAGTTCATGGGCACCTACACGCCCAACCCGTCGGACGCCATCCTGCGCTCGCGCGACAAACTGCGCGCGCACCAATTGTT
GGCCGCGCAGGGCATCGACATGCCGGTCACCGTCTTCGGCGACAACCCCGACGACACCCAGGACCTGCTCTCCATGCTCG
GCCCGCCGCCGCATGTGGTGAAGTTGAACGAGGGGGCGCAAGGCGCCGGGGTGATCCTGACCGAAAAGGCCAGCGCTTCG
CGCGGGGTGGTCGAAGCGCTGCGCGGGCTGTACGCCAACTTCATCGTGCAGGAGTTCATCGGTGAAGCCGAAGGGGCCGA
CCTGCGCTGCTTCGTGGTCGGCGACAAGGTCGTCGCAGCAATGCGCCGCCAGGCGGCCGAAGGCGATTTCCGGTCCAATC
TGCACCTGGGTGGCACTGCAGCCGTGACCGAGGCAACCGAGCAGGAGCAGGAGGTGGCGGTGCGCTCGGCACGCGCCTTG
GGCCTGACAGTGGCAGGGGTCGACCTGATCCGGTCAAAACGCGGCCCACTGGTGCTGGAGGTCAACTCCACCCCAGGTCT
GGAAGGAGTGGAAGGCGTGTGCGGCGTGGACGTCGCCGCGGCGATTGTCCAGCACCTGGAGCAGTCCGTCCGCCGATCGG
CCGGCTAA

Upstream 100 bases:

>100_bases
GGGCCTGCCGCGAACGCGCAATCGGCCTGCACTGTACGGACTTGGGTCACTTCGTCATCAGACTCTGCCCATGTCCAAGC
CGCGCCGCGTACCCGCCGCG

Downstream 100 bases:

>100_bases
CGGCTTTACCAAAAAATTAACGAAAATCTAATTACGGCCTCGCTAGCCTCTCCCGACCGTAGCTCCGCTCTCGGCAGTGA
CGGTGATCGGGATGAACTTT

Product: ribosomal protein S6 modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYATAVLRQL
EFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASAS
RGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVTEATEQEQEVAVRSARAL
GLTVAGVDLIRSKRGPLVLEVNSTPGLEGVEGVCGVDVAAAIVQHLEQSVRRSAG

Sequences:

>Translated_295_residues
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYATAVLRQL
EFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASAS
RGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVTEATEQEQEVAVRSARAL
GLTVAGVDLIRSKRGPLVLEVNSTPGLEGVEGVCGVDVAAAIVQHLEQSVRRSAG
>Mature_295_residues
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYATAVLRQL
EFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASAS
RGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVTEATEQEQEVAVRSARAL
GLTVAGVDLIRSKRGPLVLEVNSTPGLEGVEGVCGVDVAAAIVQHLEQSVRRSAG

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 [H]

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI164663810, Length=244, Percent_Identity=28.6885245901639, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI134254462, Length=257, Percent_Identity=29.1828793774319, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1787076, Length=288, Percent_Identity=57.6388888888889, Blast_Score=345, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR004666 [H]

Pfam domain/function: PF08443 RimK [H]

EC number: NA

Molecular weight: Translated: 31638; Mature: 31638

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDA
CEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCCHHH
VIPRIGASVTRYATAVLRQLEFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFG
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASASRGVVEALRGLYANFIVQEFI
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVTEATEQEQEVAVRSARAL
CCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GLTVAGVDLIRSKRGPLVLEVNSTPGLEGVEGVCGVDVAAAIVQHLEQSVRRSAG
EEHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDA
CEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCCHHH
VIPRIGASVTRYATAVLRQLEFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFG
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASASRGVVEALRGLYANFIVQEFI
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVTEATEQEQEVAVRSARAL
CCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GLTVAGVDLIRSKRGPLVLEVNSTPGLEGVEGVCGVDVAAAIVQHLEQSVRRSAG
EEHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]