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The map label for this gene is yheS [H]

Identifier: 78048852

GI number: 78048852

Start: 3765398

End: 3767362

Strand: Reverse

Name: yheS [H]

Synonym: XCV3296

Alternate gene names: 78048852

Gene position: 3767362-3765398 (Counterclockwise)

Preceding gene: 78048858

Following gene: 78048851

Centisome position: 72.75

GC content: 65.6

Gene sequence:

>1965_bases
ATGCTGCTCATCTGCTCATTCCTTTTCGTTCTATCGGACTGTCCATCAATGATTTCCCTGCGTAACTTCTCCATGCGACG
CGGCGAGCGTCTGCTGCTCTCCAACGTCGACCTGACCATGCACGCCGGCTACCGCGTCGGTGTGGTGGGCCGTAACGGCA
CCGGCAAGTCCAGCCTGTTCGCTGCGGTGAAGGGCGAGCTGGAAGCCGACAAGGGCGATGTCGATCTGCCCGGCAAGGTG
CGCACGGCCAGCGTGTCGCAGGAAACTCCCTCGCTGCCCGACCCGGCGCTGTCGTTCGTACTGGGCGGGGACATCGAGGT
GTCTGCGGTACTGCAGGAAGAAGCCGCAGCTACCGCGCGCGAGGACTGGGAGGCAGTGGCCAATGCACACCAGAAGATGG
CCGAGATCGGCGCCTACGACGCCGAAGCGCGCGCCGGCAAGTTGCTGCACGGCCTGGGCTTCCCGGCCGACACGCACCAT
CGCGCGGTGTCGTCGTTCTCCGGCGGCTGGCGGGTGCGGCTGAATCTGGCGCGCGCGCTGATGATGCCCAGCGACCTGCT
GCTGCTCGACGAGCCGACCAACCACCTGGACATGGATGCGGTGCTGTGGCTGGAGCAGTGGTTGCTCAAGTACCCGGGCA
CGCTGCTGCTGATTTCGCACGACCGCGAATTTCTCGACAACGTGGCCACCCACACCCTCCACCTGCACGGCGGCACCGCC
AAGCTGTACGTCGGCGGCTACACCGATTTCGAACGCCAGCGCATCGAGCATTTGCGCCAGCAGCAGATCGCGCACGAGAA
GGAACAGGCCGAGCGCGCGCATCTGCAGAGCTTCATCGACCGCTTCAAGGCGCAGGCCAGCAAGGCGACCCAGGCGCAGA
GCCGTATGAAGCGGCTGGCCAAGATGGCCGGTACCGAGGCGGTGCGTGCCGAGCGCGAGTTCCGCATCCAGTTCGCGCAG
CCCAGCCGGCTGCCGTTCTCGCTGATCCGGCTCAATCACGTGGAAGCCGGCTATGCCGCTGCGCCGCGGGAATCGGGAAT
CGGGAATGGGGAATCGCAAAAGCGTGGTTCCAGCGATGCCATTACCGTGCTGCATGATGTCGGATTCGGGCTAGAGGCGG
GTGACCGGATTGGTTTGCTTGGGCCCAATGGCGCAGGTAAGTCCACCCTGGTCAAGACCTTGGTGGGCGAACTGGCACCG
CTGGCAGGCGAGCGCAGCGCACATCCGGATTTGCGCATCGGCTACTTCGCCCAGCACACGGTGGAGTCGCTGCACGAAGG
CCAGTCGCCGATGGACCATTTCCGCGAGTTGTCGCCGGATGGTTCCAACCAGGCGTTCCGCGACTTTTTGGGGAAATGGA
ATTTTGCCGGCGACCGCGCCTTCGAAGTGGTGGATGGTTTCTCCGGCGGCGAGCGCGCGCGCCTGGCGCTGGCGTTGATC
GCCTGGCAGCAGCCGAACGTGCTGCTGCTGGACGAACCGACCAACCACTTGGACCTGGAAATGCGCGAAGCGCTGGCCGA
GGCGCTGAGCGATTTCGAAGGCGCCATCGTGATGGTCTCGCACGATCGCCATCTGATCGGCCTGGTCTGCGACAGTTTCT
GGCGCGTGGCCGATGGCGTGGTCGAGCCGTTCGCCGGCGACCTGGACGAATACGCCGCCTGGTTGCGGAGCCGCCCGGCC
GCGCAGGGGACCAAGCAGAAGATGGCCGAGGCGGCGCCGACCCCGCCACCGCCGACCAAGCCGCTGCCGCCGAAAAAAGC
CGTCAACCCGCACAAGCTGGCCAGTGCCGAAAAGCGCGTCGGCGAGCTGGAAGCGGCGCTCGCTGCGCTGGATCGCGAGC
TGGCCAATCCCGGCAACTACGCCGACAGCGAAAAGATGGCGGTGCTCGGACGCGACCGCGAAGCAACCGCGCAGCAGCTG
GCTGAAGCCGAGACCGCATGGATGGAGTTGATCGACGGTGCGTAA

Upstream 100 bases:

>100_bases
CAGGCAAGGCTAGGCAGGCGGCGGTCGCGGGAGGGCGAACAAGACGGCGGCCACGCTGAAGGCGCTAATTATTCGTTAAC
GCTAGAATGGCGTCGCAGGA

Downstream 100 bases:

>100_bases
GCGTCACTGACAAAAACGCCTGCGCAACCGTACGATGGCGTGTCAGATGGTCGTTGCGAGATGTACCAGGCGTACATCGC
GGTTGCCGCGCCTGGTCTAC

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MLLICSFLFVLSDCPSMISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDLPGKV
RTASVSQETPSLPDPALSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHH
RAVSSFSGGWRVRLNLARALMMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTA
KLYVGGYTDFERQRIEHLRQQQIAHEKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRIQFAQ
PSRLPFSLIRLNHVEAGYAAAPRESGIGNGESQKRGSSDAITVLHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAP
LAGERSAHPDLRIGYFAQHTVESLHEGQSPMDHFRELSPDGSNQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALI
AWQQPNVLLLDEPTNHLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWLRSRPA
AQGTKQKMAEAAPTPPPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQL
AEAETAWMELIDGA

Sequences:

>Translated_654_residues
MLLICSFLFVLSDCPSMISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDLPGKV
RTASVSQETPSLPDPALSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHH
RAVSSFSGGWRVRLNLARALMMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTA
KLYVGGYTDFERQRIEHLRQQQIAHEKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRIQFAQ
PSRLPFSLIRLNHVEAGYAAAPRESGIGNGESQKRGSSDAITVLHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAP
LAGERSAHPDLRIGYFAQHTVESLHEGQSPMDHFRELSPDGSNQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALI
AWQQPNVLLLDEPTNHLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWLRSRPA
AQGTKQKMAEAAPTPPPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQL
AEAETAWMELIDGA
>Mature_654_residues
MLLICSFLFVLSDCPSMISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDLPGKV
RTASVSQETPSLPDPALSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHH
RAVSSFSGGWRVRLNLARALMMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTA
KLYVGGYTDFERQRIEHLRQQQIAHEKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRIQFAQ
PSRLPFSLIRLNHVEAGYAAAPRESGIGNGESQKRGSSDAITVLHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAP
LAGERSAHPDLRIGYFAQHTVESLHEGQSPMDHFRELSPDGSNQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALI
AWQQPNVLLLDEPTNHLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWLRSRPA
AQGTKQKMAEAAPTPPPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQL
AEAETAWMELIDGA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=555, Percent_Identity=37.1171171171171, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI10947137, Length=548, Percent_Identity=35.036496350365, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI27881506, Length=548, Percent_Identity=35.036496350365, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI10947135, Length=558, Percent_Identity=33.3333333333333, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI69354671, Length=558, Percent_Identity=33.3333333333333, Blast_Score=250, Evalue=4e-66,
Organism=Escherichia coli, GI1789751, Length=642, Percent_Identity=45.1713395638629, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1787041, Length=550, Percent_Identity=33.8181818181818, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1787182, Length=533, Percent_Identity=29.6435272045028, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI2367384, Length=566, Percent_Identity=28.9752650176678, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87081782, Length=543, Percent_Identity=27.255985267035, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788165, Length=170, Percent_Identity=34.7058823529412, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=28.6307053941909, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788506, Length=262, Percent_Identity=24.4274809160305, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17553372, Length=546, Percent_Identity=38.0952380952381, Blast_Score=352, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17555318, Length=537, Percent_Identity=34.4506517690875, Blast_Score=316, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17559834, Length=562, Percent_Identity=33.0960854092527, Blast_Score=292, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321121, Length=578, Percent_Identity=33.9100346020761, Blast_Score=334, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6320874, Length=546, Percent_Identity=30.5860805860806, Blast_Score=273, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6325030, Length=411, Percent_Identity=31.6301703163017, Blast_Score=169, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6323278, Length=419, Percent_Identity=29.5942720763723, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324314, Length=233, Percent_Identity=30.0429184549356, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24666836, Length=542, Percent_Identity=37.2693726937269, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=560, Percent_Identity=35.5357142857143, Blast_Score=342, Evalue=5e-94,
Organism=Drosophila melanogaster, GI18859989, Length=560, Percent_Identity=35.5357142857143, Blast_Score=342, Evalue=5e-94,
Organism=Drosophila melanogaster, GI24641342, Length=551, Percent_Identity=32.3049001814882, Blast_Score=288, Evalue=8e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71413; Mature: 71413

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLICSFLFVLSDCPSMISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLF
CHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCEEEECCEEEEEEECCCCCHHHHH
AAVKGELEADKGDVDLPGKVRTASVSQETPSLPDPALSFVLGGDIEVSAVLQEEAAATAR
HHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHEECCCCEEHHHHHHHHHHHHH
EDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHHRAVSSFSGGWRVRLNLARAL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEHHHHH
MMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTA
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHEEEEEECCEE
KLYVGGYTDFERQRIEHLRQQQIAHEKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMAGTEAVRAEREFRIQFAQPSRLPFSLIRLNHVEAGYAAAPRESGIGNGESQKRGSSDA
HHHCHHHHHCCHHEEEEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCCHHCCCCCCC
ITVLHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAPLAGERSAHPDLRIGYFAQHT
EEEEHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHH
VESLHEGQSPMDHFRELSPDGSNQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALI
HHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHEEEEEE
AWQQPNVLLLDEPTNHLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGV
EECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
VEPFAGDLDEYAAWLRSRPAAQGTKQKMAEAAPTPPPPTKPLPPKKAVNPHKLASAEKRV
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQLAEAETAWMELIDGA
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLICSFLFVLSDCPSMISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLF
CHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCEEEECCEEEEEEECCCCCHHHHH
AAVKGELEADKGDVDLPGKVRTASVSQETPSLPDPALSFVLGGDIEVSAVLQEEAAATAR
HHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHEECCCCEEHHHHHHHHHHHHH
EDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHHRAVSSFSGGWRVRLNLARAL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEHHHHH
MMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTA
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHEEEEEECCEE
KLYVGGYTDFERQRIEHLRQQQIAHEKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMAGTEAVRAEREFRIQFAQPSRLPFSLIRLNHVEAGYAAAPRESGIGNGESQKRGSSDA
HHHCHHHHHCCHHEEEEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCCHHCCCCCCC
ITVLHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAPLAGERSAHPDLRIGYFAQHT
EEEEHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHH
VESLHEGQSPMDHFRELSPDGSNQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALI
HHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHEEEEEE
AWQQPNVLLLDEPTNHLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGV
EECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
VEPFAGDLDEYAAWLRSRPAAQGTKQKMAEAAPTPPPPTKPLPPKKAVNPHKLASAEKRV
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQLAEAETAWMELIDGA
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]