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The map label for this gene is ruvA [H]

Identifier: 78048836

GI number: 78048836

Start: 3747299

End: 3747883

Strand: Reverse

Name: ruvA [H]

Synonym: XCV3280

Alternate gene names: 78048836

Gene position: 3747883-3747299 (Counterclockwise)

Preceding gene: 78048837

Following gene: 78048835

Centisome position: 72.37

GC content: 67.52

Gene sequence:

>585_bases
ATGATCGGCCGTCTGCGCGGGATCCTGGCCTACAAGCAGCCGCCGTGGCTGGTGATCGACGTGGGTGGGGTGGGGTATGA
GCTGGAGGCGCCGATGAGCACCTTCTACGATCTGCCCGATGTCGGTCGCGACGTGATCCTGTTCACCCATTACGCGCAGA
AGGAAGACAGCGTCGCGCTGTACGGTTTCCTGCGCGAAGGCGAGCGGCGGTTGTTCCGCGATGTGCAGAAGGTCACCGGT
ATCGGCGCCAAGATTGCGCTGGCGGTGTTGTCCGGGGTCAGCGTGGACGAGTTCGCCCGCCTGATCACCAGCGGCGACAT
CACCGCGCTGACGCGCATTCCCGGCATCGGCAAGAAGACCGCCGAGCGCATGGTGGTGGAACTGCGCGACCGCGCGGCCG
ATTTCAGCAGCGGCGCCCCGATCACCGGCCAGTTGGGGCCCGACGCCGTTTCCGAAGCCACCGTGGCCTTGCAACAGCTG
GGCTACAAGCCGGCCGAGGCCGCCCGCATGGCGCGCGACGCCGGTGCAGAAGGCGACGAGGTCGCCACGGTCATCCGCAA
GGCACTGCAAGCCGCGCTGCGCTGA

Upstream 100 bases:

>100_bases
TACCGCTTCGGCGGTGCGCAGCCGTCGTCAACGGCAGCGAGGGAGTTCGCCAATCCCCAATCTCGAATCCCCAATCCCGG
CACCACAACGGCGGTGCCCA

Downstream 100 bases:

>100_bases
GCGCGGCCACGAACCATCGCCTGGCCGCAAAGCGGGCGCGGCCGGCACTCGGCATCGACAGGGGCGGCCCGTACACTGCG
CATCCTTGCCCGCGGCCAGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVALYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQL
GYKPAEAARMARDAGAEGDEVATVIRKALQAALR

Sequences:

>Translated_194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVALYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQL
GYKPAEAARMARDAGAEGDEVATVIRKALQAALR
>Mature_194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVALYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQL
GYKPAEAARMARDAGAEGDEVATVIRKALQAALR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=207, Percent_Identity=47.3429951690821, Blast_Score=187, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20862; Mature: 20862

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVAL
CCCCHHHHHEECCCCEEEEECCCCCEECCCCHHHHCCCCCCCCCEEEEEECCCCCCCEEE
YGFLREGERRLFRDVQKVTGIGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQLGYKPAEAARMARDAGAEGDE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
VATVIRKALQAALR
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVAL
CCCCHHHHHEECCCCEEEEECCCCCEECCCCHHHHCCCCCCCCCEEEEEECCCCCCCEEE
YGFLREGERRLFRDVQKVTGIGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQLGYKPAEAARMARDAGAEGDE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
VATVIRKALQAALR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]