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The map label for this gene is tldD [H]

Identifier: 78048479

GI number: 78048479

Start: 3323679

End: 3325124

Strand: Reverse

Name: tldD [H]

Synonym: XCV2923

Alternate gene names: 78048479

Gene position: 3325124-3323679 (Counterclockwise)

Preceding gene: 78048481

Following gene: 78048478

Centisome position: 64.21

GC content: 68.33

Gene sequence:

>1446_bases
ATGACCGATAACGCTCTCACTCTGGCCGAAACCCGGCTGCTGCTTCCTTCCGGCCTGGACGCCGGCCATCTCGACCGCAC
CTTCGGCGCCCTGCTGGGCCCGGGCATCGACTTCGGCGATCTGTATTTCCAGCATTCGCGGCGCGAGAGCTGGAGCGTGG
AAGACGGCATCGTCAAGGACGGCGCGCATTCCATCGAACAAGGCGTGGGCGTGCGCGCAATCGCCGGCGAAAAAACCGGC
TTCGCCTATTCCGACGACATCCACCGCGATGCGCTGCTGGAAGCGGCACAGTCCGCGCGCGCGATCTCGCGCGAGGGCGG
GGCGCAATCCACCCGCGCGCTGGTACGCGGCAATGGCCGTGCGCTGTACCCGGCCACCGATCCCATCGACGACATGGACA
GCGCCACCAAGGTGGACCTGCTGCGCCGAATCGACCAGTTCCTGCGCGCTGCCGACCCGCGCGTCAAGCAGGTGATGGTG
AGCCTGTCCGGCGGCGTGGACACGGTGCTGATCGCCCGCAGCGACGGCGTGCTGGCAGCAGACGTGCGGCCGCTGGTGCG
CTTGAACGTGCAGGTGATCGTCGAACAGGGCGGCCGGCGCGAATCCGGTTATTCCGGCGGCGGCGGCCGCTATGGCTATG
CCGAACTGTTCGCCGACGGCCGCCCGGAAGGGTTTGCGCGCGAAGCGCTGCGCCAGGCGCTGGTGAATCTGGACGCGATC
CCGGCGCCGGCTGGGGTGATGCCGGTGGTGCTCGGTCCGGGCTGGCCCGGCGTGCTGTTGCACGAGGCGGTGGGGCATGG
CCTGGAAGGCGACTTCAACCGCAAGGGCACCAGCGTCTACGCCGGCCGCATCGGCGAGCGCGTGGCCTCGCCGGGCGTGA
CCATTGTCGATGACGGCACCCTGGACGGGCGCCGCGGCTCGCTCAATATCGACGACGAAGGCACGCCCAGCCAGTGCACC
ACGCTGATCGAAGACGGCGTGCTGGTGGGCTACATGCAGGACAGCCACAACGCGCGCCTGATGGGCGTGGCGCCCACCGG
CAACGGCCGCCGCGAATCGTTCGCGCACCTGACCATGCCGCGCATGACCAACACCTACATGCGCGCCGGCCAGCACGACC
CGGAAGAGATGATCCGCTCGGTCAAGAAGGGCATCTACGCGGTGAACTTCGGTGGCGGCCAGGTCGACATCACCAGCGGC
AAATACGTATTTTCGGCCACCGAGGCCTACCTGATCGAAGACGGCAAGGTCACCGCACCGGTCAAGGGCGCCACCCTGAT
CGGCAACGGCCCGGAAACCATGCAGAAGGTGCGCATGATCGGCAACGACCTGGCGCTGGACGAAGGCGTGGGCGTGTGCG
GCAAGGACGGGCAGAGCGTGCCGGTCGGCGTCGGCCAGCCGTCGCTGCTGATCGACGGCATCACGGTTGGCGGAACGCAG
GCCTGA

Upstream 100 bases:

>100_bases
ATGCGCGGGCGATCGGTGAAGAACTGGCCAGCGATGATAGCCGTGCGCATGTTCAGCCGAACGACTTGTCTCCCCGGCGC
GCGGGCCCCATCCTGACCAC

Downstream 100 bases:

>100_bases
GATGCGGGGAATCGGGAATCGGGATTTGGGAATCGTAGCGGCAGGAGCGCAAAGCAGTGCGTCAGGCCTTTGCGATGCAC
TGGTCCCGATGCGCTTGCGG

Product: putative modulator of DNA gyrase TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTG
FAYSDDIHRDALLEAAQSARAISREGGAQSTRALVRGNGRALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMV
SLSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPSQCT
TLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSG
KYVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
A

Sequences:

>Translated_481_residues
MTDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTG
FAYSDDIHRDALLEAAQSARAISREGGAQSTRALVRGNGRALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMV
SLSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPSQCT
TLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSG
KYVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
A
>Mature_480_residues
TDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTGF
AYSDDIHRDALLEAAQSARAISREGGAQSTRALVRGNGRALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMVS
LSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAIP
APAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPSQCTT
LIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSGK
YVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=479, Percent_Identity=62.0041753653445, Blast_Score=569, Evalue=1e-163,
Organism=Escherichia coli, GI1790682, Length=319, Percent_Identity=23.5109717868339, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50734; Mature: 50603

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKD
CCCCCEEHHHHEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHC
GAHSIEQGVGVRAIAGEKTGFAYSDDIHRDALLEAAQSARAISREGGAQSTRALVRGNGR
CHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
ALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMVSLSGGVDTVLIARSDGVLAA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCEEEE
DVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
CCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGT
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCC
LDGRRGSLNIDDEGTPSQCTTLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMP
CCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCCHHHEEECC
RMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSGKYVFSATEAYLIEDGKVTAP
HHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCEEECC
VKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
A
C
>Mature Secondary Structure 
TDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKD
CCCCEEHHHHEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHC
GAHSIEQGVGVRAIAGEKTGFAYSDDIHRDALLEAAQSARAISREGGAQSTRALVRGNGR
CHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
ALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMVSLSGGVDTVLIARSDGVLAA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCEEEE
DVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
CCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGT
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCC
LDGRRGSLNIDDEGTPSQCTTLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMP
CCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCCHHHEEECC
RMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSGKYVFSATEAYLIEDGKVTAP
HHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCEEECC
VKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]