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The map label for this gene is slyD [H]

Identifier: 78048462

GI number: 78048462

Start: 3309112

End: 3309591

Strand: Reverse

Name: slyD [H]

Synonym: XCV2906

Alternate gene names: 78048462

Gene position: 3309591-3309112 (Counterclockwise)

Preceding gene: 78048465

Following gene: 78048461

Centisome position: 63.91

GC content: 63.12

Gene sequence:

>480_bases
ATGAAGATCGAAAAAGACAGCGTCGTCCGCTTCCATTACACCGTTTCGGAGATCGGCCAGGAGCCGATCGAGAGCTCCAA
GGAGCGTGACCCGTTGGCGATCATGATCGGCCACGGCAACATCATCCCGGGCCTGGAAGCGGCCATGATGGGGAAGGCGG
CCGGCGAGAGCTTCGGCGTGGACGTCAAGGCCGCCGACGCCTACGGCGAATACCGCGAAGGCCTGAGCCAGCGCGTGCCC
AAGAAGCATTTCGGCGCCACCAAGCTGGTGCCCGGCACCCAGGTCGTGCTGCAGACCAACTTCGGCCCGCGCGCAGTGAC
GGTGCAGAAAGTCGGCATGAGCGTGGTCGATGTGGACCTCAATCACCCCATGGCCGGCAAGGATCTGCATTTCGACGTGG
AGATCGTCGAAGTGCGTGAAGCCACCGCAGAAGAACGCGACCACGGCCATGTGCACGGCGACGGCGGTCATCACCACTAA

Upstream 100 bases:

>100_bases
ATAATGGGCGGTTCGAAAGGTCGCCATGATGGCGGCGCACCCGGCGGCCGACAAGCCGTCCTCAACCGTCTGCCACCGGG
CAGCCCATTCAGAGCCAGGC

Downstream 100 bases:

>100_bases
GGGTGGGGCACGCGCTCGCATGGCGGTTGGACGGGTGCGACGCCTGCGCGCCACTGACGTAGGCCGGTCATCCGGCGCTG
CGCTGGCGCATGCACTCCAC

Product: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMGKAAGESFGVDVKAADAYGEYREGLSQRVP
KKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH

Sequences:

>Translated_159_residues
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMGKAAGESFGVDVKAADAYGEYREGLSQRVP
KKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH
>Mature_159_residues
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMGKAAGESFGVDVKAADAYGEYREGLSQRVP
KKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=146, Percent_Identity=43.8356164383562, Blast_Score=104, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17284; Mature: 17284

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMGKAAGESFGV
CCCCCCCEEEEEEEHHHHCCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCC
DVKAADAYGEYREGLSQRVPKKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDL
EEEEHHHHHHHHHHHHHCCCHHHCCCEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEEC
NHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH
CCCCCCCCEEEEEEEEEEHHHHHHHCCCCCEECCCCCCC
>Mature Secondary Structure
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMGKAAGESFGV
CCCCCCCEEEEEEEHHHHCCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCC
DVKAADAYGEYREGLSQRVPKKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDL
EEEEHHHHHHHHHHHHHCCCHHHCCCEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEEC
NHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH
CCCCCCCCEEEEEEEEEEHHHHHHHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]