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The map label for this gene is lhr [H]

Identifier: 78048183

GI number: 78048183

Start: 2959960

End: 2964354

Strand: Reverse

Name: lhr [H]

Synonym: XCV2627

Alternate gene names: 78048183

Gene position: 2964354-2959960 (Counterclockwise)

Preceding gene: 78048185

Following gene: 78048181

Centisome position: 57.24

GC content: 68.24

Gene sequence:

>4395_bases
ATGCATCCTGTCCTGCAACACTTCCATCCTGTGGTCGCTGCGTGGTTCGCGCAGACCTTCGCTGCGCCGACACCGGCGCA
GGTCGCCGCGTGGCCGGCGATCCAGGCCGGACGCCACACGCTGGTGGCCGCGCCGACCGGCTCGGGCAAGACGCTGACGG
CCTTCTTCGCCGCCATCGATGCATTGATTCGCGACGGGCTGGCCAACGGCGGTGCGTTGCCCGACGAAACCCGTGTGGTC
TACGTCTCGCCGTTGAAGGCCTTGTCCAACGACATCCACCTCAATCTGGACGCGCCCTTGCAGGGCATCCGTGCGGCGCT
GGTCGCCGGCGGCTTGCCGGATGTGCCGATTCGTACCGCGGTGCGTACCGGCGATACCCCGCAGCGCGAGCGCGCGCAGG
CGCGTCGCACGCCGCCGCATATTCTGGTGACCACCCCGGAGTCGCTGTACGTACTGTTGGGGTCGGCATCCGGGCGCGCG
TCGCTGCAGCATGTGCGCACCGTGATCGTCGATGAAATCCACGCGGTGGCGTCGGACAAGCGCGGCAGCCACCTGAGCCT
GACGCTGGAGCGCTTGCAGCGGCTGGTCGCGCAGCCGATCACGCGGGTGGGGCTGTCGGCCACCCAGAAGCCCATCGAAA
CGGTGGCGCAATTCCTGGTCGGTGTCGACGCAGACGGCGTGCCGCCGCCGTGCGAGATCGTCGATATCGGCTACACCCGC
AAGCGTGATCTGGCCCTGGCGTTGCCGCCCACGCCGCTGAGCGTGGTGATGTCCAACGACCAGTGGCTGCAGGTGTATGC
CGATGTGGCTGCACTGGCGCAGCAACATCGCACCACGCTGGTGTTCGTCAACACACGGCGCATGGCCGAACGCGCGGCGC
GGCATCTGGGCGATCTGCTCGGCAAGCAGCGCGTGTCGGCGCATCACGGCAGCCTGTCGCGCGAGACGCGCCTGCTGGCC
GTGCAACGGCTCAAGGCCGGCGATCTCACCGTGTTGGTGGCGACCGCATCGCTGGAACTGGGGCTGGATATCGGCGATGT
CGATCTGGTCTGCCAGCTCGGTTCGCCGCGCTCGATTGCCACCTTCCTGCAACGCGCCGGGCGTTCCGGACACAAGGTCG
GCGGCACGCCCAAGGCGCGCCTGTTTCCGCAGACCCGCGACGAACTGGTCGAATGCGCCGCGCTGCTGGACAGCATCCGC
CGCGGCGAACTGGATGCCTTGCGCATTGTGACGGCGCCGGTGGATGTGCTGGCGCAGCAGATCGTTGCCGAAGCCGCATG
CGAAGACTGGGACGAAGATGCGCTGTTCGCGCTGGTGCGGCGCGCGTGGCCGTTCGCCGGGTTGAGCCGTGCCACCTTCG
ACAGCGTGGTGCGCATGTTGTGCGATGGCTTCAGCACCCGCCTCGGTCCGCGCGCCGGGTATCTGCATCGCGATGCCGTG
CACCGGCGCCTGCATGCACGGCGCGGTGCGCGCATGACGGCGCTCACTTCCGGCGGCACCATTCCCGAAACCGGCGACTA
CAGCGTGGTGCTGGAACCGCAGGCCGAAAAGATCGGCACGGTGAACGAGGATTTCGCCGTTGAAAGCCTCACCGGCGATG
TGTTCCAGCTCGGCAATGCGAGCTACCGCATCCTGCGCGTGGAGGCCGGGCGCGTGCGCGTGGAAGATGCCAAGGGCGCG
CCGCCGAACATTCCGTTCTGGCTGGGCGAAGCGCCGGGTCGCAGCGATGAGCTGTCTGCGGCGGTGTCGCGCCTGCGTGG
CGAGATTGCCGCGCGGCTGGACACCGCGCCGCACCAATCCGCGCGCGACTGGCTGCAGCGCGAGCTGGAGATGTCTGCCG
AAGCGGCGCGGCAACTGGTGGATTATCTGGCAAACGCTTGCACGGCATTGGGCGCGATGCCCACCCAGCAGTGTCTGGTC
ATGGAGCGCTTCTTCGATGCCAGCGGCGGTACCCAGCTGGTCATCCATTCGCCGTACGGCAGCCGCATCAATCGTGCGTG
GGGGTTGGCGCTGCGCAAGCGCTTCTGCCGCACCTTCAATTTCGAATTGCAGGCGGCGGCCACCGAAGATGCGATTGTGT
TGTCGCTGTCGACCAGTCATAGCTTTGCGCTGGAAGAGGTTGGCCGTTACCTGCATTCGTCGTCGGCCGAGCATGTATTG
ATCCAGGCATTGCTGGACGCACCACTATTCGGCGTGCGCTGGCGCTGGAACGCCACCAACGCAATGGCGCTGCCGCGCTT
CAGTGGCGGCAACAAGGTGGCGCCGCAGTTGCAACGCATGAAGTCCGAAGATTTGCTCGCCACGGTATTCCCGGACCAGG
TGGCCTGTGCGGAGAATCTGGTCGGCGAACGCGAGGTGCCCGACCACCCGTTGGTGGCACAGACCCTGGAAGATTGCCTG
CATCACGCCATGGATAGCGACGGCTGGCTGCAGGTTTTGCGCGGCCTGGAATCGGGCGCGGTGACGCTGGTCGCGCGCGA
CCTGGCCGCGCCGTCGCCGCTGGCCGCCGAAGCCTTGAATGCGCGTCCGTATGCATTTCTCGACGATGCGCCGCTGGAAG
AACGCCGTACCCAGGCCGTGCAAAGTCGCCGCTACACGCCGCAGACCAGCGACGACCTGGGCCAGCTCGATCCGCAGGCG
ATTGCCGCAGTGTGCGAAGAGGCCTGGCCACAGCCGCGCGATGCCGAAGAAATGCACGAGGCATTGGTGGGGCTGGGCGT
GTTGCCGGTCGCAGAGGCTACCGACGCGCAGTGGCAGGCATGGTTGGCCGCGCTGGCCGCAGCGGGTCGTGCCAGCTGCA
TTGCCTTGCACGGCAGCCCGGCGCTGTGGGTCAGCGCCGAGCGTATCGACTGGTTCTTGCCGTTGTATCGGCAAGCAACT
GTGCAGCCGCCGTTGCAGGCGCCGGCCGATTGCCGCGTTGCCGACTGGCAGCGCGACTGGGCGGTGCGCGAACTGCTGCG
CGGGCGCTTGTCCGCGGTCGGCCCGGCACAGGTGCCGGCCTTGTCCCACGCATTGCAGGTGCCGGAAGCAGAAATCGCGC
TCGCACTGGCGGCCTTGCAACGCGAGGGCTACGTCATGGCCGGGCAGTTCAATGCGCATGTGCAGGGCGAAGAGTGGTGC
GAGCGCCATCTGTTGGCACGCATCCACCGCTACACGCTGGGGCGCCTGCGCCGCGAGATCGAACCGGTATCGCAACGCGA
TTACGCGCGTTTTCTGTTCGAGTGGCAGCACGTGGACAGCAGCAGCCGGGTGGCCGGGCCGGATGCGCTGGCCGGTGTGG
TGGGGCAGCTCGAAGGCTTCGAGGCGCCTGCGGTGCTGTGGGAGAGCGAGCTATTGCCGGCGCGCATCCGCGACTATCAA
CCGGCCTGGCTGGATGAGTTGTGCACTGCCGGGCGCACGCTGTGGGCACGCCTGCGGCCCGGCGGCGGCCGCAGCGGCGC
TGCACTGCGCAGTACGCCGATCGTGCTGCTGCCACGACGCGAAGCGCAGCATTGGAGCGCGTTGGCGCGCGATGCCGACG
ACGCGCCATTGAGCTCCCGCGCGCAACGGGTCATGCAGGTGCTGCAGCAGCAAGGCGCGCTGTTCTTCGACGAAATCGCC
GACGCGGCACATCTGATGAACACCGAGCTGGAAGATGCCTTGAGCGAGCTGGTGATGCGTGGCCGCGCGCATTGCGACAG
CTATGCCGGCCTGCGCGCGCTGCTGGTGCCTGCGTCCAAGCGACCGTCGGCACTGTCGCGGCAGCGTCGCCGTGCCAGCG
CACTGGGCATCCGCGATGCGGGCCGCTGGGCACCGGTGCGGGCGCTGCCCGACCTGCCGCTTGCCGAAGCCGCGCAGCGC
CATCAGGACACGCTCGAACACGTCGCGCGCACGCTGCTGCGGCGCTACGGCGTGGTGTGCTGGCGGCTGCTCGAACGCGA
GGCTGCATGGCTGCCGCCATGGCGGGAATTGCTGCGCATGTATCAACGGCTGGAAGCGCGCGGCGAAATCCGCGGCGGGC
GGTTTATCGCCGGGCTGTCCGGCGAGCAGTTTGCGTTGCCGGACGCGATTGCGGCCCTGCGCCGTGCGCGCGCGCAGCCG
TTGCCGCAGCAATGGATCTGCGTCAGTGCCAGCGATCCAAGCAATCTGCTCGGCAGTCTGCTGCCGGGCGAGCGGGTCGC
GCGCGTGCCGGGCAATCGCGTCGCTTCGCTGGATGGGCTGCCGATGGCGGTCTGGGCGGCAGACCGCTTCCAGGCCTTGC
AGGAGCTCACCCCCGAGCAGGCCGAGCAGGCGTTGCGTCTGCTACAGCGCGGACCGGGCGCGGCCGAGCAATCGCCGATG
GAGCGCTGGTTGGCTCAATCGCCCGCGGGCGCCGTGCCTTTTCCGGTCACGCGCGGAAGCGGACGCGACACATAG

Upstream 100 bases:

>100_bases
GCTTGTCTGGACCGCTGCGCAGCCCCATTGATTATGGTTCACGCCGAGTTATATCCGCGCGCCTTGCCGTCATGATGAGC
AATGGTGTCGGGCATTGCCA

Downstream 100 bases:

>100_bases
CGGCTATCTGCAACCACCCAGCGCCATGGCGCATCCACGGCCTTGCGGATGCCGATGCGCGGCGTTGCCACTGGATGGGA
GGGGGGCGGCACGCCGTCGT

Product: ATP-dependent DNA helicase Lhr

Products: NA

Alternate protein names: Large helicase-related protein [H]

Number of amino acids: Translated: 1464; Mature: 1464

Protein sequence:

>1464_residues
MHPVLQHFHPVVAAWFAQTFAAPTPAQVAAWPAIQAGRHTLVAAPTGSGKTLTAFFAAIDALIRDGLANGGALPDETRVV
YVSPLKALSNDIHLNLDAPLQGIRAALVAGGLPDVPIRTAVRTGDTPQRERAQARRTPPHILVTTPESLYVLLGSASGRA
SLQHVRTVIVDEIHAVASDKRGSHLSLTLERLQRLVAQPITRVGLSATQKPIETVAQFLVGVDADGVPPPCEIVDIGYTR
KRDLALALPPTPLSVVMSNDQWLQVYADVAALAQQHRTTLVFVNTRRMAERAARHLGDLLGKQRVSAHHGSLSRETRLLA
VQRLKAGDLTVLVATASLELGLDIGDVDLVCQLGSPRSIATFLQRAGRSGHKVGGTPKARLFPQTRDELVECAALLDSIR
RGELDALRIVTAPVDVLAQQIVAEAACEDWDEDALFALVRRAWPFAGLSRATFDSVVRMLCDGFSTRLGPRAGYLHRDAV
HRRLHARRGARMTALTSGGTIPETGDYSVVLEPQAEKIGTVNEDFAVESLTGDVFQLGNASYRILRVEAGRVRVEDAKGA
PPNIPFWLGEAPGRSDELSAAVSRLRGEIAARLDTAPHQSARDWLQRELEMSAEAARQLVDYLANACTALGAMPTQQCLV
MERFFDASGGTQLVIHSPYGSRINRAWGLALRKRFCRTFNFELQAAATEDAIVLSLSTSHSFALEEVGRYLHSSSAEHVL
IQALLDAPLFGVRWRWNATNAMALPRFSGGNKVAPQLQRMKSEDLLATVFPDQVACAENLVGEREVPDHPLVAQTLEDCL
HHAMDSDGWLQVLRGLESGAVTLVARDLAAPSPLAAEALNARPYAFLDDAPLEERRTQAVQSRRYTPQTSDDLGQLDPQA
IAAVCEEAWPQPRDAEEMHEALVGLGVLPVAEATDAQWQAWLAALAAAGRASCIALHGSPALWVSAERIDWFLPLYRQAT
VQPPLQAPADCRVADWQRDWAVRELLRGRLSAVGPAQVPALSHALQVPEAEIALALAALQREGYVMAGQFNAHVQGEEWC
ERHLLARIHRYTLGRLRREIEPVSQRDYARFLFEWQHVDSSSRVAGPDALAGVVGQLEGFEAPAVLWESELLPARIRDYQ
PAWLDELCTAGRTLWARLRPGGGRSGAALRSTPIVLLPRREAQHWSALARDADDAPLSSRAQRVMQVLQQQGALFFDEIA
DAAHLMNTELEDALSELVMRGRAHCDSYAGLRALLVPASKRPSALSRQRRRASALGIRDAGRWAPVRALPDLPLAEAAQR
HQDTLEHVARTLLRRYGVVCWRLLEREAAWLPPWRELLRMYQRLEARGEIRGGRFIAGLSGEQFALPDAIAALRRARAQP
LPQQWICVSASDPSNLLGSLLPGERVARVPGNRVASLDGLPMAVWAADRFQALQELTPEQAEQALRLLQRGPGAAEQSPM
ERWLAQSPAGAVPFPVTRGSGRDT

Sequences:

>Translated_1464_residues
MHPVLQHFHPVVAAWFAQTFAAPTPAQVAAWPAIQAGRHTLVAAPTGSGKTLTAFFAAIDALIRDGLANGGALPDETRVV
YVSPLKALSNDIHLNLDAPLQGIRAALVAGGLPDVPIRTAVRTGDTPQRERAQARRTPPHILVTTPESLYVLLGSASGRA
SLQHVRTVIVDEIHAVASDKRGSHLSLTLERLQRLVAQPITRVGLSATQKPIETVAQFLVGVDADGVPPPCEIVDIGYTR
KRDLALALPPTPLSVVMSNDQWLQVYADVAALAQQHRTTLVFVNTRRMAERAARHLGDLLGKQRVSAHHGSLSRETRLLA
VQRLKAGDLTVLVATASLELGLDIGDVDLVCQLGSPRSIATFLQRAGRSGHKVGGTPKARLFPQTRDELVECAALLDSIR
RGELDALRIVTAPVDVLAQQIVAEAACEDWDEDALFALVRRAWPFAGLSRATFDSVVRMLCDGFSTRLGPRAGYLHRDAV
HRRLHARRGARMTALTSGGTIPETGDYSVVLEPQAEKIGTVNEDFAVESLTGDVFQLGNASYRILRVEAGRVRVEDAKGA
PPNIPFWLGEAPGRSDELSAAVSRLRGEIAARLDTAPHQSARDWLQRELEMSAEAARQLVDYLANACTALGAMPTQQCLV
MERFFDASGGTQLVIHSPYGSRINRAWGLALRKRFCRTFNFELQAAATEDAIVLSLSTSHSFALEEVGRYLHSSSAEHVL
IQALLDAPLFGVRWRWNATNAMALPRFSGGNKVAPQLQRMKSEDLLATVFPDQVACAENLVGEREVPDHPLVAQTLEDCL
HHAMDSDGWLQVLRGLESGAVTLVARDLAAPSPLAAEALNARPYAFLDDAPLEERRTQAVQSRRYTPQTSDDLGQLDPQA
IAAVCEEAWPQPRDAEEMHEALVGLGVLPVAEATDAQWQAWLAALAAAGRASCIALHGSPALWVSAERIDWFLPLYRQAT
VQPPLQAPADCRVADWQRDWAVRELLRGRLSAVGPAQVPALSHALQVPEAEIALALAALQREGYVMAGQFNAHVQGEEWC
ERHLLARIHRYTLGRLRREIEPVSQRDYARFLFEWQHVDSSSRVAGPDALAGVVGQLEGFEAPAVLWESELLPARIRDYQ
PAWLDELCTAGRTLWARLRPGGGRSGAALRSTPIVLLPRREAQHWSALARDADDAPLSSRAQRVMQVLQQQGALFFDEIA
DAAHLMNTELEDALSELVMRGRAHCDSYAGLRALLVPASKRPSALSRQRRRASALGIRDAGRWAPVRALPDLPLAEAAQR
HQDTLEHVARTLLRRYGVVCWRLLEREAAWLPPWRELLRMYQRLEARGEIRGGRFIAGLSGEQFALPDAIAALRRARAQP
LPQQWICVSASDPSNLLGSLLPGERVARVPGNRVASLDGLPMAVWAADRFQALQELTPEQAEQALRLLQRGPGAAEQSPM
ERWLAQSPAGAVPFPVTRGSGRDT
>Mature_1464_residues
MHPVLQHFHPVVAAWFAQTFAAPTPAQVAAWPAIQAGRHTLVAAPTGSGKTLTAFFAAIDALIRDGLANGGALPDETRVV
YVSPLKALSNDIHLNLDAPLQGIRAALVAGGLPDVPIRTAVRTGDTPQRERAQARRTPPHILVTTPESLYVLLGSASGRA
SLQHVRTVIVDEIHAVASDKRGSHLSLTLERLQRLVAQPITRVGLSATQKPIETVAQFLVGVDADGVPPPCEIVDIGYTR
KRDLALALPPTPLSVVMSNDQWLQVYADVAALAQQHRTTLVFVNTRRMAERAARHLGDLLGKQRVSAHHGSLSRETRLLA
VQRLKAGDLTVLVATASLELGLDIGDVDLVCQLGSPRSIATFLQRAGRSGHKVGGTPKARLFPQTRDELVECAALLDSIR
RGELDALRIVTAPVDVLAQQIVAEAACEDWDEDALFALVRRAWPFAGLSRATFDSVVRMLCDGFSTRLGPRAGYLHRDAV
HRRLHARRGARMTALTSGGTIPETGDYSVVLEPQAEKIGTVNEDFAVESLTGDVFQLGNASYRILRVEAGRVRVEDAKGA
PPNIPFWLGEAPGRSDELSAAVSRLRGEIAARLDTAPHQSARDWLQRELEMSAEAARQLVDYLANACTALGAMPTQQCLV
MERFFDASGGTQLVIHSPYGSRINRAWGLALRKRFCRTFNFELQAAATEDAIVLSLSTSHSFALEEVGRYLHSSSAEHVL
IQALLDAPLFGVRWRWNATNAMALPRFSGGNKVAPQLQRMKSEDLLATVFPDQVACAENLVGEREVPDHPLVAQTLEDCL
HHAMDSDGWLQVLRGLESGAVTLVARDLAAPSPLAAEALNARPYAFLDDAPLEERRTQAVQSRRYTPQTSDDLGQLDPQA
IAAVCEEAWPQPRDAEEMHEALVGLGVLPVAEATDAQWQAWLAALAAAGRASCIALHGSPALWVSAERIDWFLPLYRQAT
VQPPLQAPADCRVADWQRDWAVRELLRGRLSAVGPAQVPALSHALQVPEAEIALALAALQREGYVMAGQFNAHVQGEEWC
ERHLLARIHRYTLGRLRREIEPVSQRDYARFLFEWQHVDSSSRVAGPDALAGVVGQLEGFEAPAVLWESELLPARIRDYQ
PAWLDELCTAGRTLWARLRPGGGRSGAALRSTPIVLLPRREAQHWSALARDADDAPLSSRAQRVMQVLQQQGALFFDEIA
DAAHLMNTELEDALSELVMRGRAHCDSYAGLRALLVPASKRPSALSRQRRRASALGIRDAGRWAPVRALPDLPLAEAAQR
HQDTLEHVARTLLRRYGVVCWRLLEREAAWLPPWRELLRMYQRLEARGEIRGGRFIAGLSGEQFALPDAIAALRRARAQP
LPQQWICVSASDPSNLLGSLLPGERVARVPGNRVASLDGLPMAVWAADRFQALQELTPEQAEQALRLLQRGPGAAEQSPM
ERWLAQSPAGAVPFPVTRGSGRDT

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI169218225, Length=402, Percent_Identity=22.8855721393035, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI40217847, Length=402, Percent_Identity=23.134328358209, Blast_Score=74, Evalue=1e-12,
Organism=Escherichia coli, GI1787942, Length=1495, Percent_Identity=31.0367892976589, Blast_Score=545, Evalue=1e-155,
Organism=Escherichia coli, GI1787016, Length=380, Percent_Identity=26.8421052631579, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537127, Length=352, Percent_Identity=29.2613636363636, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537519, Length=364, Percent_Identity=26.3736263736264, Blast_Score=75, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320497, Length=369, Percent_Identity=27.10027100271, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI9755332, Length=353, Percent_Identity=25.7790368271955, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6321710, Length=386, Percent_Identity=26.9430051813472, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24647182, Length=368, Percent_Identity=26.6304347826087, Blast_Score=84, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 159929; Mature: 159929

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPVLQHFHPVVAAWFAQTFAAPTPAQVAAWPAIQAGRHTLVAAPTGSGKTLTAFFAAID
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCEEEEEECCCCCCHHHHHHHHHH
ALIRDGLANGGALPDETRVVYVSPLKALSNDIHLNLDAPLQGIRAALVAGGLPDVPIRTA
HHHHHCCCCCCCCCCCCEEEEECCHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHH
VRTGDTPQRERAQARRTPPHILVTTPESLYVLLGSASGRASLQHVRTVIVDEIHAVASDK
CCCCCCCHHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
RGSHLSLTLERLQRLVAQPITRVGLSATQKPIETVAQFLVGVDADGVPPPCEIVDIGYTR
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
KRDLALALPPTPLSVVMSNDQWLQVYADVAALAQQHRTTLVFVNTRRMAERAARHLGDLL
CCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHH
GKQRVSAHHGSLSRETRLLAVQRLKAGDLTVLVATASLELGLDIGDVDLVCQLGSPRSIA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCHHHH
TFLQRAGRSGHKVGGTPKARLFPQTRDELVECAALLDSIRRGELDALRIVTAPVDVLAQQ
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
IVAEAACEDWDEDALFALVRRAWPFAGLSRATFDSVVRMLCDGFSTRLGPRAGYLHRDAV
HHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
HRRLHARRGARMTALTSGGTIPETGDYSVVLEPQAEKIGTVNEDFAVESLTGDVFQLGNA
HHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCHHHHHHCCHHHHCCCC
SYRILRVEAGRVRVEDAKGAPPNIPFWLGEAPGRSDELSAAVSRLRGEIAARLDTAPHQS
CEEEEEEECCEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
ARDWLQRELEMSAEAARQLVDYLANACTALGAMPTQQCLVMERFFDASGGTQLVIHSPYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
SRINRAWGLALRKRFCRTFNFELQAAATEDAIVLSLSTSHSFALEEVGRYLHSSSAEHVL
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
IQALLDAPLFGVRWRWNATNAMALPRFSGGNKVAPQLQRMKSEDLLATVFPDQVACAENL
HHHHHCCCCCCEEEEECCCCCEECCCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHH
VGEREVPDHPLVAQTLEDCLHHAMDSDGWLQVLRGLESGAVTLVARDLAAPSPLAAEALN
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHC
ARPYAFLDDAPLEERRTQAVQSRRYTPQTSDDLGQLDPQAIAAVCEEAWPQPRDAEEMHE
CCCCEEECCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCHHHHHH
ALVGLGVLPVAEATDAQWQAWLAALAAAGRASCIALHGSPALWVSAERIDWFLPLYRQAT
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHCC
VQPPLQAPADCRVADWQRDWAVRELLRGRLSAVGPAQVPALSHALQVPEAEIALALAALQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
REGYVMAGQFNAHVQGEEWCERHLLARIHRYTLGRLRREIEPVSQRDYARFLFEWQHVDS
HCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SSRVAGPDALAGVVGQLEGFEAPAVLWESELLPARIRDYQPAWLDELCTAGRTLWARLRP
CCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCCCHHHHHHHHCCHHEEEEECC
GGGRSGAALRSTPIVLLPRREAQHWSALARDADDAPLSSRAQRVMQVLQQQGALFFDEIA
CCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
DAAHLMNTELEDALSELVMRGRAHCDSYAGLRALLVPASKRPSALSRQRRRASALGIRDA
HHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCC
GRWAPVRALPDLPLAEAAQRHQDTLEHVARTLLRRYGVVCWRLLEREAAWLPPWRELLRM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YQRLEARGEIRGGRFIAGLSGEQFALPDAIAALRRARAQPLPQQWICVSASDPSNLLGSL
HHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHC
LPGERVARVPGNRVASLDGLPMAVWAADRFQALQELTPEQAEQALRLLQRGPGAAEQSPM
CCCCCEECCCCCCEECCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHH
ERWLAQSPAGAVPFPVTRGSGRDT
HHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHPVLQHFHPVVAAWFAQTFAAPTPAQVAAWPAIQAGRHTLVAAPTGSGKTLTAFFAAID
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCEEEEEECCCCCCHHHHHHHHHH
ALIRDGLANGGALPDETRVVYVSPLKALSNDIHLNLDAPLQGIRAALVAGGLPDVPIRTA
HHHHHCCCCCCCCCCCCEEEEECCHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHH
VRTGDTPQRERAQARRTPPHILVTTPESLYVLLGSASGRASLQHVRTVIVDEIHAVASDK
CCCCCCCHHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
RGSHLSLTLERLQRLVAQPITRVGLSATQKPIETVAQFLVGVDADGVPPPCEIVDIGYTR
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
KRDLALALPPTPLSVVMSNDQWLQVYADVAALAQQHRTTLVFVNTRRMAERAARHLGDLL
CCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHH
GKQRVSAHHGSLSRETRLLAVQRLKAGDLTVLVATASLELGLDIGDVDLVCQLGSPRSIA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCHHHH
TFLQRAGRSGHKVGGTPKARLFPQTRDELVECAALLDSIRRGELDALRIVTAPVDVLAQQ
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
IVAEAACEDWDEDALFALVRRAWPFAGLSRATFDSVVRMLCDGFSTRLGPRAGYLHRDAV
HHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
HRRLHARRGARMTALTSGGTIPETGDYSVVLEPQAEKIGTVNEDFAVESLTGDVFQLGNA
HHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCHHHHHHCCHHHHCCCC
SYRILRVEAGRVRVEDAKGAPPNIPFWLGEAPGRSDELSAAVSRLRGEIAARLDTAPHQS
CEEEEEEECCEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
ARDWLQRELEMSAEAARQLVDYLANACTALGAMPTQQCLVMERFFDASGGTQLVIHSPYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
SRINRAWGLALRKRFCRTFNFELQAAATEDAIVLSLSTSHSFALEEVGRYLHSSSAEHVL
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
IQALLDAPLFGVRWRWNATNAMALPRFSGGNKVAPQLQRMKSEDLLATVFPDQVACAENL
HHHHHCCCCCCEEEEECCCCCEECCCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHH
VGEREVPDHPLVAQTLEDCLHHAMDSDGWLQVLRGLESGAVTLVARDLAAPSPLAAEALN
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHC
ARPYAFLDDAPLEERRTQAVQSRRYTPQTSDDLGQLDPQAIAAVCEEAWPQPRDAEEMHE
CCCCEEECCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCHHHHHH
ALVGLGVLPVAEATDAQWQAWLAALAAAGRASCIALHGSPALWVSAERIDWFLPLYRQAT
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHCC
VQPPLQAPADCRVADWQRDWAVRELLRGRLSAVGPAQVPALSHALQVPEAEIALALAALQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
REGYVMAGQFNAHVQGEEWCERHLLARIHRYTLGRLRREIEPVSQRDYARFLFEWQHVDS
HCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SSRVAGPDALAGVVGQLEGFEAPAVLWESELLPARIRDYQPAWLDELCTAGRTLWARLRP
CCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCCCHHHHHHHHCCHHEEEEECC
GGGRSGAALRSTPIVLLPRREAQHWSALARDADDAPLSSRAQRVMQVLQQQGALFFDEIA
CCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
DAAHLMNTELEDALSELVMRGRAHCDSYAGLRALLVPASKRPSALSRQRRRASALGIRDA
HHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCC
GRWAPVRALPDLPLAEAAQRHQDTLEHVARTLLRRYGVVCWRLLEREAAWLPPWRELLRM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YQRLEARGEIRGGRFIAGLSGEQFALPDAIAALRRARAQPLPQQWICVSASDPSNLLGSL
HHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHC
LPGERVARVPGNRVASLDGLPMAVWAADRFQALQELTPEQAEQALRLLQRGPGAAEQSPM
CCCCCEECCCCCCEECCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHH
ERWLAQSPAGAVPFPVTRGSGRDT
HHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7559321; 9097039; 9278503; 1460056 [H]