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The map label for this gene is htpX [H]

Identifier: 78048152

GI number: 78048152

Start: 2926326

End: 2927204

Strand: Reverse

Name: htpX [H]

Synonym: XCV2596

Alternate gene names: 78048152

Gene position: 2927204-2926326 (Counterclockwise)

Preceding gene: 78048156

Following gene: 78048148

Centisome position: 56.53

GC content: 64.85

Gene sequence:

>879_bases
ATGTTCAACCGCATTTTCCTGTTCCTGCTGACCAATCTTGCGGTGCTGATGCTCGCCGGCATCGTCATGTCGTTGCTGGG
CGTCAATCCCGCGCAGATGAGTGGCCTGTTGGTGATGGCCGCCATCTTCGGTTTCGGCGGCTCGTTCATTTCCTTGCTGC
TGTCCAAGTTCATGGCCAAGCGCAGCACCGGTGCGCAGGTCATCACCGAGCCGCGCACGCCGACCGAGCGCTGGTTGCTG
GAGACCGTGCGCCGCCACGCCCAGGCTGCCGGCATCGGCATGCCGGAAGTAGCGGTCTACGACGGCCCGGAAATCAACGC
GTTCGCCACCGGCGCCAACCGCAACGACGCCCTGGTGGCGGTGTCCACCGGCCTGCTGCAGAACATGGACCAGGATGAAG
CCGAGGCGGTGCTTGGCCACGAGATCGCCCACGTGGCCAACGGCGATATGGTCACCATGGCGCTGCTGCAGGGCGTCCTC
AATACCTTCGTGATCGTGCTCGCCCGCGTGGTCGGCGGCATTATCGACAGCGCCTTGTCGGGCAACCGCGAGGGCGGTCG
TGGCTTTGCGTACTACATCATCGTGTTTGCGTTGGAGATGGTGTTCGGCTTGTTCGCGACCATGATTGCGATGTGGTTCT
CGCGACGCCGCGAATTCCGCGCCGATGCCGGTGGCGCGCAGCTGGCCGGCCGCAGCAAGATGATCGCTGCGCTGGAGCGG
CTGTCGCTCAACCATGGCCAGAACACCTTGCCCTCGCAAGTGCAGGCGTTCGGCATCTCCGGTGGGGTGGGCGAGGGCTT
GCGCCGGCTGTTCCTGAGCCATCCGCCGCTTACCGAACGCATCGCTGCGCTGCGCGCCGCCAGTGGTAGCGCCATGTAA

Upstream 100 bases:

>100_bases
CATGGGCAGCTGAATCGTCGGTCAGGTGCTTGCTTGATTTCAAGCCGCAACACCCGCAGATCCGCACCAGTTCACCCCGC
ATCCGTGGAGCCATCGCGCC

Downstream 100 bases:

>100_bases
GGTGTCGGAACTCCGGCTGCCTGGCAGGCAACAAAAAACCCGCGCAATGCGGGTTTTTTGTTATTTAGCGAGGTTGCGAA
CGAGCGGGCGCGCCGGCTTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFNRIFLFLLTNLAVLMLAGIVMSLLGVNPAQMSGLLVMAAIFGFGGSFISLLLSKFMAKRSTGAQVITEPRTPTERWLL
ETVRRHAQAAGIGMPEVAVYDGPEINAFATGANRNDALVAVSTGLLQNMDQDEAEAVLGHEIAHVANGDMVTMALLQGVL
NTFVIVLARVVGGIIDSALSGNREGGRGFAYYIIVFALEMVFGLFATMIAMWFSRRREFRADAGGAQLAGRSKMIAALER
LSLNHGQNTLPSQVQAFGISGGVGEGLRRLFLSHPPLTERIAALRAASGSAM

Sequences:

>Translated_292_residues
MFNRIFLFLLTNLAVLMLAGIVMSLLGVNPAQMSGLLVMAAIFGFGGSFISLLLSKFMAKRSTGAQVITEPRTPTERWLL
ETVRRHAQAAGIGMPEVAVYDGPEINAFATGANRNDALVAVSTGLLQNMDQDEAEAVLGHEIAHVANGDMVTMALLQGVL
NTFVIVLARVVGGIIDSALSGNREGGRGFAYYIIVFALEMVFGLFATMIAMWFSRRREFRADAGGAQLAGRSKMIAALER
LSLNHGQNTLPSQVQAFGISGGVGEGLRRLFLSHPPLTERIAALRAASGSAM
>Mature_292_residues
MFNRIFLFLLTNLAVLMLAGIVMSLLGVNPAQMSGLLVMAAIFGFGGSFISLLLSKFMAKRSTGAQVITEPRTPTERWLL
ETVRRHAQAAGIGMPEVAVYDGPEINAFATGANRNDALVAVSTGLLQNMDQDEAEAVLGHEIAHVANGDMVTMALLQGVL
NTFVIVLARVVGGIIDSALSGNREGGRGFAYYIIVFALEMVFGLFATMIAMWFSRRREFRADAGGAQLAGRSKMIAALER
LSLNHGQNTLPSQVQAFGISGGVGEGLRRLFLSHPPLTERIAALRAASGSAM

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=287, Percent_Identity=55.0522648083624, Blast_Score=316, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31156; Mature: 31156

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNRIFLFLLTNLAVLMLAGIVMSLLGVNPAQMSGLLVMAAIFGFGGSFISLLLSKFMAK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RSTGAQVITEPRTPTERWLLETVRRHAQAAGIGMPEVAVYDGPEINAFATGANRNDALVA
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCCCEEE
VSTGLLQNMDQDEAEAVLGHEIAHVANGDMVTMALLQGVLNTFVIVLARVVGGIIDSALS
EHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNREGGRGFAYYIIVFALEMVFGLFATMIAMWFSRRREFRADAGGAQLAGRSKMIAALER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHH
LSLNHGQNTLPSQVQAFGISGGVGEGLRRLFLSHPPLTERIAALRAASGSAM
HHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFNRIFLFLLTNLAVLMLAGIVMSLLGVNPAQMSGLLVMAAIFGFGGSFISLLLSKFMAK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RSTGAQVITEPRTPTERWLLETVRRHAQAAGIGMPEVAVYDGPEINAFATGANRNDALVA
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCCCEEE
VSTGLLQNMDQDEAEAVLGHEIAHVANGDMVTMALLQGVLNTFVIVLARVVGGIIDSALS
EHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNREGGRGFAYYIIVFALEMVFGLFATMIAMWFSRRREFRADAGGAQLAGRSKMIAALER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHH
LSLNHGQNTLPSQVQAFGISGGVGEGLRRLFLSHPPLTERIAALRAASGSAM
HHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]