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The map label for this gene is ubiG [H]

Identifier: 78048130

GI number: 78048130

Start: 2901451

End: 2902170

Strand: Reverse

Name: ubiG [H]

Synonym: XCV2574

Alternate gene names: 78048130

Gene position: 2902170-2901451 (Counterclockwise)

Preceding gene: 78048131

Following gene: 78048129

Centisome position: 56.04

GC content: 64.58

Gene sequence:

>720_bases
ATGAATTCGAATACGCACGCCAAATCCAGCAATTTCCATCAGAGCGAGCTGGATAAATTCGCCGCGCTGGCCAACCGCTG
GTGGGATGCCGACGGCCCGCAGAAGCCGCTGCATGCGCTCAATCCTGTGCGTCTGGAGTATGTGTCCACGCGGCTGGAAC
TTGCCGGTGCGCGCGTGCTCGATGTCGGCTGCGGTGGCGGTTTGCTCAGCGAATCGATGGCACGTCTGGGCGCGCAGGTG
ACTGCGATCGACCTGGCGCCGGAACTGGTGAAGGTGGCGCGTCTGCACAGCCTGGAATCGGGCGTGCAGGTCGACTATCG
CGTGCAATCGGTGGAAGACCTGGCCGCCGAACAGCCGGGCAGCTTCGATACGGTGACCTGCATGGAAATGCTCGAACACG
TGCCGGATCCGACCGCGATCATCCGTGCCTGCGCCAGCCTGCTCAAGCCGGGCGGCAAGCTGTTCCTGTCCACGCTCAAT
CGCACCCCTGCCGCGTTCGCGCTGGCGGTGGTGGGCGCCGAATACATCGCGCGCCTGCTGCCCAAGGGCACGCACCACTA
CAAGGATTTCATCAAGCCGGCCGAGCTTGCGGCGTGGCTGCGCAACGCCGGGCTGCAGCTCGAAGACGTCAGCGGCATGC
TGTACGAGCCGTGGCGCAATCGCGCCCGCCTGTCCTCGCGTACCGAGGTGAATTACCTGGCGTATGCGGTGAAGCCGTGA

Upstream 100 bases:

>100_bases
CATGGATACCGCCGCCCTGGTCGCCAATGCGCGGCAGTGGCGCGAACGCATCCGCACCGTCCGCGCCTGAGCGCGCGTCA
CCGCATCACGGAGCCCCCGC

Downstream 100 bases:

>100_bases
TGGGCGGGGATTCGGGAATCGGGAATCGGGAATCGCAAAGGCGGTTGGCTGAGGGTTTGAGATTTTCTCGTTTCGGGTGG
AGTGCATGCAGTTGCAGGCC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNSNTHAKSSNFHQSELDKFAALANRWWDADGPQKPLHALNPVRLEYVSTRLELAGARVLDVGCGGGLLSESMARLGAQV
TAIDLAPELVKVARLHSLESGVQVDYRVQSVEDLAAEQPGSFDTVTCMEMLEHVPDPTAIIRACASLLKPGGKLFLSTLN
RTPAAFALAVVGAEYIARLLPKGTHHYKDFIKPAELAAWLRNAGLQLEDVSGMLYEPWRNRARLSSRTEVNYLAYAVKP

Sequences:

>Translated_239_residues
MNSNTHAKSSNFHQSELDKFAALANRWWDADGPQKPLHALNPVRLEYVSTRLELAGARVLDVGCGGGLLSESMARLGAQV
TAIDLAPELVKVARLHSLESGVQVDYRVQSVEDLAAEQPGSFDTVTCMEMLEHVPDPTAIIRACASLLKPGGKLFLSTLN
RTPAAFALAVVGAEYIARLLPKGTHHYKDFIKPAELAAWLRNAGLQLEDVSGMLYEPWRNRARLSSRTEVNYLAYAVKP
>Mature_239_residues
MNSNTHAKSSNFHQSELDKFAALANRWWDADGPQKPLHALNPVRLEYVSTRLELAGARVLDVGCGGGLLSESMARLGAQV
TAIDLAPELVKVARLHSLESGVQVDYRVQSVEDLAAEQPGSFDTVTCMEMLEHVPDPTAIIRACASLLKPGGKLFLSTLN
RTPAAFALAVVGAEYIARLLPKGTHHYKDFIKPAELAAWLRNAGLQLEDVSGMLYEPWRNRARLSSRTEVNYLAYAVKP

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=237, Percent_Identity=40.9282700421941, Blast_Score=196, Evalue=2e-50,
Organism=Escherichia coli, GI1788564, Length=237, Percent_Identity=52.3206751054852, Blast_Score=267, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI115533050, Length=236, Percent_Identity=34.3220338983051, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324476, Length=271, Percent_Identity=32.8413284132841, Blast_Score=152, Evalue=6e-38,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=36.4754098360656, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24585589, Length=265, Percent_Identity=33.5849056603774, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26162; Mature: 26162

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNTHAKSSNFHQSELDKFAALANRWWDADGPQKPLHALNPVRLEYVSTRLELAGARVL
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCEEE
DVGCGGGLLSESMARLGAQVTAIDLAPELVKVARLHSLESGVQVDYRVQSVEDLAAEQPG
EECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCC
SFDTVTCMEMLEHVPDPTAIIRACASLLKPGGKLFLSTLNRTPAAFALAVVGAEYIARLL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PKGTHHYKDFIKPAELAAWLRNAGLQLEDVSGMLYEPWRNRARLSSRTEVNYLAYAVKP
CCCCHHHHHHCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure
MNSNTHAKSSNFHQSELDKFAALANRWWDADGPQKPLHALNPVRLEYVSTRLELAGARVL
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCEEE
DVGCGGGLLSESMARLGAQVTAIDLAPELVKVARLHSLESGVQVDYRVQSVEDLAAEQPG
EECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCC
SFDTVTCMEMLEHVPDPTAIIRACASLLKPGGKLFLSTLNRTPAAFALAVVGAEYIARLL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PKGTHHYKDFIKPAELAAWLRNAGLQLEDVSGMLYEPWRNRARLSSRTEVNYLAYAVKP
CCCCHHHHHHCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]