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The map label for this gene is zupT [H]

Identifier: 78047982

GI number: 78047982

Start: 2754385

End: 2755203

Strand: Reverse

Name: zupT [H]

Synonym: XCV2426

Alternate gene names: 78047982

Gene position: 2755203-2754385 (Counterclockwise)

Preceding gene: 78047983

Following gene: 78047981

Centisome position: 53.21

GC content: 62.15

Gene sequence:

>819_bases
ATGCTTGCAGTGTCATCACACAATCTCTGGATCGCGCTTGCGGTCACGCTGGCGGCCGGGCTGGCAACCGGGCTCGGCAG
CCTCATGGTGGTGTTCGCCAAAAAGCCCAATCCGCGGCTGTTGGCATTCGGCCTGGCCTTCGCCGGCGGCGCCATGGTGT
ACGTGTCGCTCACCGAGATCCTCAACAAGTCGATCGCCGCGTTTTCCCAGGCCTACAACGACAAGCTCGGCTTTACCTTC
GGCACACTGACCTTTCTGGGCGGCATGCTGCTGATCATGGTGATCGACCGCCTGGTGCCAAATCCGCACCAGAGTTTGTC
CAGCGACGATCCGCAGTTTCGCGAAGACAACCGGGCCTATATCCGCCGGGTTGGCCTGATGACCGCCGTCGCGATCACCG
CGCACAATTTCCCGGAAGGACTGGCGACTTTCTTCGCCACGCTTGAAAGCCCAGCGGTCGGCATGCCGCTGGCGTTCGCG
ATCGCCATCCACAATATTCCCGAAGGCATCGCGATCGCGGTGCCGGTGTATTTCGCCACGCGCAACAAGTTCTATGCGGT
GGGCGCCAGCCTGCTCAGCGGGTTGGCCGAACCGGTCGGTGCAGGCATCGGATATCTGGCCTTGTCCAGCGTGCTCTCGG
ATGCGGTCTTCGGCACCGTGTTCGGGCTGATCTCCGGGGTCATGGTGTTTCTGGCGCTGGACGAATTACTGCCGGCTGCC
AAGCGCTACGCACAAGGTCACGAGACCGTGTATGGCCTGGTCTCGGGCATGGGAACGCTGGCGATCAGCCTGGTGTTGTT
CCGTTTCGCAACCCCGTGA

Upstream 100 bases:

>100_bases
ATGGCCATCCTGCTTCCGCGGAGGGGTGTGCGTATCTGGCGAGCTGCAGTTGCCACGCTCTCCGCAGGAAGTTCTTCATT
CCACGAGGACGTCGCGCCAC

Downstream 100 bases:

>100_bases
AGCGCGTCATGCGCGGGCATCACCACTCGAGATGGCCTGGCGCGAAGTCTGTTGCAGCAAGTGCAGACAATGCCGCTTCA
GAAGCCCGATCGCTGTGTTG

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEILNKSIAAFSQAYNDKLGFTF
GTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAYIRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFA
IAIHNIPEGIAIAVPVYFATRNKFYAVGASLLSGLAEPVGAGIGYLALSSVLSDAVFGTVFGLISGVMVFLALDELLPAA
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP

Sequences:

>Translated_272_residues
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEILNKSIAAFSQAYNDKLGFTF
GTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAYIRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFA
IAIHNIPEGIAIAVPVYFATRNKFYAVGASLLSGLAEPVGAGIGYLALSSVLSDAVFGTVFGLISGVMVFLALDELLPAA
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP
>Mature_272_residues
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEILNKSIAAFSQAYNDKLGFTF
GTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAYIRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFA
IAIHNIPEGIAIAVPVYFATRNKFYAVGASLLSGLAEPVGAGIGYLALSSVLSDAVFGTVFGLISGVMVFLALDELLPAA
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577422, Length=136, Percent_Identity=34.5588235294118, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI229577418, Length=136, Percent_Identity=34.5588235294118, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1789419, Length=264, Percent_Identity=38.2575757575758, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17507805, Length=305, Percent_Identity=25.9016393442623, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24652846, Length=158, Percent_Identity=31.6455696202532, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28605; Mature: 28605

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEI
CCEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEHHHHHCCHHHHHHHHHH
LNKSIAAFSQAYNDKLGFTFGTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHCCHHH
IRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFAIAIHNIPEGIAIAVPVYFAT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEHC
RNKFYAVGASLLSGLAEPVGAGIGYLALSSVLSDAVFGTVFGLISGVMVFLALDELLPAA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEI
CCEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEHHHHHCCHHHHHHHHHH
LNKSIAAFSQAYNDKLGFTFGTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHCCHHH
IRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFAIAIHNIPEGIAIAVPVYFAT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEHC
RNKFYAVGASLLSGLAEPVGAGIGYLALSSVLSDAVFGTVFGLISGVMVFLALDELLPAA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]