BacMap

Definition	Xanthomonas campestris pv. vesicatoria str. 85-10 chromosome, complete genome.
Accession	NC_007508
Length	5,178,466

Click here to switch to the map view.

The map label for this gene is yvrD [H]

Identifier: 78047728

GI number: 78047728

Start: 2497903

End: 2498682

Strand: Reverse

Name: yvrD [H]

Synonym: XCV2172

Alternate gene names: 78047728

Gene position: 2498682-2497903 (Counterclockwise)

Preceding gene: 78047729

Following gene: 78047727

Centisome position: 48.25

GC content: 65.51

Gene sequence:

>780_bases
ATGAAGGCAGATCCGACCGAATTCGCCGGCAAGCGCGTGCTCGTCAGCGGTGGCACCAAAGGGCTGGGCCGTGCCACGGT
CGAGCGCTTCCTCGCTGGCGGCGCCCGTGTCATCACCGCGGCTCGCACGATCAACACCCCTATCGAAGGCGTCGAATACG
TGCAGGCCGACCTGACGACCGCGGAAGGCGGCCAGGCGTTTGCCACGGCGGCGCTTGAGCGGCTGGGTGGCGTCGACATC
CTGGCCCATGTCGTCGGTGGCTCCTCTTCGCCAGCCGGAGGTTTCGCCGCGCTGACGGACGAGCACTGGCTTGCCGAACT
GAACCTCAACCTGCTGGCGACCGTGCGACTCGATCGGCTGTTGATTCCGCAGATGCTGGAGCGTGGCAGCGGCGTTGTGG
TGCACATCACCTCGATTCAGTCGGTTCTGCCGTTGCCCGAGTCGACGACAGGCTATGCCGCCGCCAAGGCCGCGCTGCGG
ACCTACAGCAAGTCGATTTCCAAAGAGCTCGGCCCCAAGGGCGTGCGGGTCAATGCCGTCTCACCGGGCTGGATCATGAC
CGAGGCCATGCAGGACTTTCTGGAAACGCTCAGCAAATCTGGCGGCACGATCGAGCAAGCGCGTCAGTCTGTGCTCGATG
CCCTGGGCGGTATCCCGATCGGGCGCGCAGCCGAACCTGAAGAGGTGGCCGATCTTATCGCCTACCTCGCTGCCGATCGT
GCGGCGGCGATCCACGGCGCCGAGTTCGTCATCGATGGCGGCACGATCAGGACGGTGTAG

Upstream 100 bases:

>100_bases
GCCCCACCCATGGCGACTTCCCCGGTAGCCCGCTGCGCTTCACCTATCGTTTCACGATGGTCAACGATGCCATCAAGACC
CTGGAGACAAGGGTATGGGC

Downstream 100 bases:

>100_bases
GCATGGCTTTGCGGTATTCCCGCAAGCGCGCCGCTCACCTCCCCTTGCCGGTGGATGAAGTGGTTGCCCAATGCCAGCCC
GCGGATTGATTGAAGAGAGG

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKADPTEFAGKRVLVSGGTKGLGRATVERFLAGGARVITAARTINTPIEGVEYVQADLTTAEGGQAFATAALERLGGVDI
LAHVVGGSSSPAGGFAALTDEHWLAELNLNLLATVRLDRLLIPQMLERGSGVVVHITSIQSVLPLPESTTGYAAAKAALR
TYSKSISKELGPKGVRVNAVSPGWIMTEAMQDFLETLSKSGGTIEQARQSVLDALGGIPIGRAAEPEEVADLIAYLAADR
AAAIHGAEFVIDGGTIRTV

Sequences:

>Translated_259_residues
MKADPTEFAGKRVLVSGGTKGLGRATVERFLAGGARVITAARTINTPIEGVEYVQADLTTAEGGQAFATAALERLGGVDI
LAHVVGGSSSPAGGFAALTDEHWLAELNLNLLATVRLDRLLIPQMLERGSGVVVHITSIQSVLPLPESTTGYAAAKAALR
TYSKSISKELGPKGVRVNAVSPGWIMTEAMQDFLETLSKSGGTIEQARQSVLDALGGIPIGRAAEPEEVADLIAYLAADR
AAAIHGAEFVIDGGTIRTV
>Mature_259_residues
MKADPTEFAGKRVLVSGGTKGLGRATVERFLAGGARVITAARTINTPIEGVEYVQADLTTAEGGQAFATAALERLGGVDI
LAHVVGGSSSPAGGFAALTDEHWLAELNLNLLATVRLDRLLIPQMLERGSGVVVHITSIQSVLPLPESTTGYAAAKAALR
TYSKSISKELGPKGVRVNAVSPGWIMTEAMQDFLETLSKSGGTIEQARQSVLDALGGIPIGRAAEPEEVADLIAYLAADR
AAAIHGAEFVIDGGTIRTV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=265, Percent_Identity=29.0566037735849, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=30.3149606299213, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI66933014, Length=205, Percent_Identity=29.7560975609756, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI126723750, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI59889578, Length=241, Percent_Identity=27.3858921161826, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=26.865671641791, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031737, Length=262, Percent_Identity=25.9541984732824, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=255, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI226371731, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI10190704, Length=267, Percent_Identity=24.7191011235955, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=217, Percent_Identity=27.6497695852535, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=29.6875, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=31.0077519379845, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=27.9693486590038, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=30.5882352941176, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=26.7175572519084, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=267, Percent_Identity=26.5917602996255, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367175, Length=258, Percent_Identity=29.8449612403101, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367365, Length=261, Percent_Identity=28.3524904214559, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790717, Length=268, Percent_Identity=23.8805970149254, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788459, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787891, Length=253, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=23.3716475095785, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=277, Percent_Identity=32.129963898917, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=29.7397769516729, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=31.9852941176471, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=30.3703703703704, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=29.4776119402985, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=29.4776119402985, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=29.3233082706767, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=30.4832713754647, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=266, Percent_Identity=29.6992481203008, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=29.2592592592593, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=26.6917293233083, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=29.520295202952, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=28.3018867924528, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=27.5735294117647, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=29.7397769516729, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=28.3088235294118, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=27.3408239700375, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=29.2592592592593, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=28.6792452830189, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=265, Percent_Identity=27.9245283018868, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=25.968992248062, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=199, Percent_Identity=28.1407035175879, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=198, Percent_Identity=26.7676767676768, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=27.0916334661355, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=28.1632653061224, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=265, Percent_Identity=23.7735849056604, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=29.6875, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=29.8449612403101, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=28.1853281853282, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571526, Length=265, Percent_Identity=30.188679245283, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=27.6923076923077, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358495, Length=219, Percent_Identity=29.6803652968037, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24644339, Length=264, Percent_Identity=26.8939393939394, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=261, Percent_Identity=25.6704980842912, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644337, Length=126, Percent_Identity=35.7142857142857, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 26856; Mature: 26856

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADPTEFAGKRVLVSGGTKGLGRATVERFLAGGARVITAARTINTPIEGVEYVQADLTT
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHEEEHHHHHCCCHHHHHHHHHHCCC
AEGGQAFATAALERLGGVDILAHVVGGSSSPAGGFAALTDEHWLAELNLNLLATVRLDRL
CCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCCHHEEHHCCCEEEHHHHHHH
LIPQMLERGSGVVVHITSIQSVLPLPESTTGYAAAKAALRTYSKSISKELGPKGVRVNAV
HHHHHHHCCCCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
SPGWIMTEAMQDFLETLSKSGGTIEQARQSVLDALGGIPIGRAAEPEEVADLIAYLAADR
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AAAIHGAEFVIDGGTIRTV
HHHCCCCEEEECCCEEECC
>Mature Secondary Structure
MKADPTEFAGKRVLVSGGTKGLGRATVERFLAGGARVITAARTINTPIEGVEYVQADLTT
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHEEEHHHHHCCCHHHHHHHHHHCCC
AEGGQAFATAALERLGGVDILAHVVGGSSSPAGGFAALTDEHWLAELNLNLLATVRLDRL
CCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCCHHEEHHCCCEEEHHHHHHH
LIPQMLERGSGVVVHITSIQSVLPLPESTTGYAAAKAALRTYSKSISKELGPKGVRVNAV
HHHHHHHCCCCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
SPGWIMTEAMQDFLETLSKSGGTIEQARQSVLDALGGIPIGRAAEPEEVADLIAYLAADR
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AAAIHGAEFVIDGGTIRTV
HHHCCCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]