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The map label for this gene is nreB [H]

Identifier: 78047596

GI number: 78047596

Start: 2321826

End: 2323958

Strand: Reverse

Name: nreB [H]

Synonym: XCV2040

Alternate gene names: 78047596

Gene position: 2323958-2321826 (Counterclockwise)

Preceding gene: 78047598

Following gene: 78047595

Centisome position: 44.88

GC content: 66.39

Gene sequence:

>2133_bases
ATGGCCGCATCGCCAGCACTCAAGGTCGTCCGCGGATCCATGCAACAGCCCGTCGCCGCGCCCGCATTTTCGTCTGCCCC
CGTCTCCTGCCTCCGTCTGGCCGAGCGCCTGCAGCAAGGCTTGTGGACACTGACCGGCCTGTACCTGCTGGTTGGCGTGA
TCTGGCTGCTGCTGGGCAACCGGCTGCTCAACCTGGCCGGCGCCGCCATGCCGGAGCGCTGGTCGGATGCGAGCTTTCTG
GTGCTGTCCAGCATCGTCATCCACCTGGTGCTGCGCCGCTTTACCGGCTTGATCGTGGACGAGTACGCCCAGCTGGCGCA
GTCCGAGGCGTTGCTGCAAGCCAAGTTCCTGGCATTGCCCAGCCCGGCCTTCATTTACGACCTGGCCACCATGCGCATCC
TCGACGCCAATCCGGCGGCGCTGGAATTCTTCGGCTGGGAGCGCGACGAGTTCCTGCAGCAGACGCTGCAGGCGATCTGG
CCCAATGCCGATGGCGAGCGGCTGGAAGAGATCATTGCGCAGATCCGTGGCAAGGGGGATGCCACCTGCGTGTTGAACGA
GGACCTGATGACGCGCAGCGGCCCGCGGCATGTCGAGGTGCGCAGCAACCAGCTGCATCTGGCCAGCGGTCCTGCCCGCC
TGGTCGTCACCGTAGACCGCAGCGAAGAGCGCCGGGCGCAGGATCTGCGCGACGAGGCGCTCGAACGCCTGGAAGAGGCG
CAGAGCATCGCGCGGCTGGGCTCCTGGCAACTGGATCGCACCACTGGCCTGGGGCGCTATTCGCCAGCGGTCTACCGCCT
GCTGGGGCGCAGCGTGCCGATGCACCGTCGTGAGCATCGGCTGGAAGAATTGCTGACCGCCTCCGACAGCGCGACCCAGG
TGCGCATCGAACGCATGATCGAAGACATGTGTACCGGTGGCGAGGTGCAGATCGATGTGCTGCTGCCGCTGACCGGTGGC
GATTCGCAACCGCGCACGGTGCATCTGCGCGCCGAAAGCGTGACCAGCCCCAGCGGCGTGCGCCATGTGCACGGCACCTT
GCAGGACGTGAGCGAACGCGAGCAATCGCGCCGGCTGCTGCGCGAACGCGAGGAGCAGTTTCGCGAGTTGGTGCGCGTGC
TGCCCGACGGTGTGCTGATTCTCGCCGACGAGCATGTGATGTATGCCAACGCGGCCGGCTCGGCCCAGTTCGGCTTCCAG
GGCGAAACCATCCTGGGCGAACCACTGCAGACCCTGGTGGGCGACAACGACCTGCCGGTGGTGCGCGAATACCTGCGCGC
AGGCAGCGATCGCAATGAGCCGGTGTCCAGCGCACGCGCGATGCGTCGTCGCGACGGCAGCACCTTCTACGCAGGTCTGT
CGGCCGGCGACATCCGCTACGGCGGACGCAGCTGCAAGTTGCTGGTGGTGCGCGATCTGAGCGAACCCGAGCGCATGCGC
GATGCCCTGGCCGAGAGCAATGCCGAACTGCAGGCGATGGCCAAACGTCTGTTTTCGTTGCAGGAAGATGAGCGGCGTGC
CATCTCGCGCGACCTGCATGACGACATCGGGCAAGCGATCACTGCGATGAAGTTGTCTGCGCACGCAGCCCTGGATGAGC
CGGACGCGGACGCGCGCCGCGAGGACTTGCTGGAAGTCGTGTCGCTGGCCGACACCACGGTGACCAAGCTGCGCAATCTG
TCGATGCTGTTGCGCCCGCCACAACTCGATGCCCTGGGCCTGGAGGCAGCGCTGCGTTGGCAGGCATCGATGCTGTTCCG
CGCCTCGCAGGTTCGGCTGGAGCTCGATATTCAGGCACTCGAGGAACGGCCGGGCAACGAGATCGAACAGGCCTGCTTCC
GGATCGCGCAGGAAAGCCTGACCAATGCGTTGCGGCACGCCTGCGCCGGCGAAGTGCACCTGCGTCTGCATTCGATCGAT
GGCGACAGTTTCCGCCTGGAAGTCAGCGACGACGGCGATGGGTTCGAGCCGGAGGGTCCGCGTGGGCTGGGGCTGATCGT
GATGCGTGAGCGTGCGCAAACCGTCGGCGGCACGCTCGCGATAGAATCAGCCCCCGGAGCAGGCACGCGCGTGACGTTGC
GCCTGCCCTATCACCCGGTCGGCGAGTCCGTCCACGACGATGGTGGACGTTGA

Upstream 100 bases:

>100_bases
TCGACCCCGGCCTCGGAGTCGCAATGGATAACGGCCGTGCCGGCCAATAGTTGAGCCACCTGTTGCGAGCTGGACCGAAC
CGGCCCGAGTTACGGCTAAG

Downstream 100 bases:

>100_bases
GTCATGTGGAGTCCCGTAATCCCGCCCGGACTGGAAATCGTCAAGCCCACCCGGCTTGGCGCGGGCAACCCCGAATTGCT
GCACCTGGTGGATGCGGCCG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MAASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLQQGLWTLTGLYLLVGVIWLLLGNRLLNLAGAAMPERWSDASFL
VLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFLALPSPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIW
PNADGERLEEIIAQIRGKGDATCVLNEDLMTRSGPRHVEVRSNQLHLASGPARLVVTVDRSEERRAQDLRDEALERLEEA
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQVRIERMIEDMCTGGEVQIDVLLPLTGG
DSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLLREREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQ
GETILGEPLQTLVGDNDLPVVREYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLSEPERMR
DALAESNAELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARREDLLEVVSLADTTVTKLRNL
SMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQALEERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSID
GDSFRLEVSDDGDGFEPEGPRGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR

Sequences:

>Translated_710_residues
MAASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLQQGLWTLTGLYLLVGVIWLLLGNRLLNLAGAAMPERWSDASFL
VLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFLALPSPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIW
PNADGERLEEIIAQIRGKGDATCVLNEDLMTRSGPRHVEVRSNQLHLASGPARLVVTVDRSEERRAQDLRDEALERLEEA
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQVRIERMIEDMCTGGEVQIDVLLPLTGG
DSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLLREREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQ
GETILGEPLQTLVGDNDLPVVREYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLSEPERMR
DALAESNAELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARREDLLEVVSLADTTVTKLRNL
SMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQALEERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSID
GDSFRLEVSDDGDGFEPEGPRGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR
>Mature_709_residues
AASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLQQGLWTLTGLYLLVGVIWLLLGNRLLNLAGAAMPERWSDASFLV
LSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFLALPSPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIWP
NADGERLEEIIAQIRGKGDATCVLNEDLMTRSGPRHVEVRSNQLHLASGPARLVVTVDRSEERRAQDLRDEALERLEEAQ
SIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQVRIERMIEDMCTGGEVQIDVLLPLTGGD
SQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLLREREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQG
ETILGEPLQTLVGDNDLPVVREYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLSEPERMRD
ALAESNAELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARREDLLEVVSLADTTVTKLRNLS
MLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQALEERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSIDG
DSFRLEVSDDGDGFEPEGPRGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=236, Percent_Identity=36.4406779661017, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787474, Length=257, Percent_Identity=28.0155642023346, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788812, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78559; Mature: 78428

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLQQGLWTLTGLYLLVGVIWLLLGN
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLNLAGAAMPERWSDASFLVLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFLALP
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIWPNADGERLEEIIAQIRGKGD
CCHHHHHHHHHEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
ATCVLNEDLMTRSGPRHVEVRSNQLHLASGPARLVVTVDRSEERRAQDLRDEALERLEEA
EEEEECCHHHHCCCCCEEEEECCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQVRIERMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
EDMCTGGEVQIDVLLPLTGGDSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLL
HHHCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
REREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQGETILGEPLQTLVGDNDLPV
HHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCCCHH
VREYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLSEPERMR
HHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEECCCCEEEEEEECCCCHHHHH
DALAESNAELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARR
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
EDLLEVVSLADTTVTKLRNLSMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHH
EERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSIDGDSFRLEVSDDGDGFEPEGP
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCC
RGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR
CCCEEEEEEHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLQQGLWTLTGLYLLVGVIWLLLGN
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLNLAGAAMPERWSDASFLVLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFLALP
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIWPNADGERLEEIIAQIRGKGD
CCHHHHHHHHHEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
ATCVLNEDLMTRSGPRHVEVRSNQLHLASGPARLVVTVDRSEERRAQDLRDEALERLEEA
EEEEECCHHHHCCCCCEEEEECCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQVRIERMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
EDMCTGGEVQIDVLLPLTGGDSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLL
HHHCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
REREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQGETILGEPLQTLVGDNDLPV
HHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCCCHH
VREYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLSEPERMR
HHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEECCCCEEEEEEECCCCHHHHH
DALAESNAELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARR
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
EDLLEVVSLADTTVTKLRNLSMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHH
EERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSIDGDSFRLEVSDDGDGFEPEGP
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCC
RGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR
CCCEEEEEEHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA