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The map label for this gene is kdsB1 [H]

Identifier: 78047559

GI number: 78047559

Start: 2285418

End: 2286167

Strand: Reverse

Name: kdsB1 [H]

Synonym: XCV2003

Alternate gene names: 78047559

Gene position: 2286167-2285418 (Counterclockwise)

Preceding gene: 78047560

Following gene: 78047558

Centisome position: 44.15

GC content: 60.53

Gene sequence:

>750_bases
ATGACTTACGCCATCATCATCCCCGCGCGGCGCGACTCTTCGCGCCTGCCCGGAAAACCGCTGATCGAGTTGGGCGGCGT
GCCCATGATCGTGCGCACCTATCAGCAATGCGCCAAAGCGGCGCCAGCCGAGCGCATTCTCGTCGCCACCGATTGCGATG
TGATTCAACGTACCTGCGAGCAGGCCGGCATCCGCACCTTGATGACCTCCAGCGACTGCCTGACCGGCACCGATCGTGTT
GCCGAGGTCGCGCAGCAGCTCGATGTGGACACCTATATCAATGTGCAAGGTGACGATCCGCTATTCAATCCGCAGGACGT
GCGTCTGCTGATCGACGCTGCGGCAGCTTCACCGAATGATGTCATCAACGGTTACTGCCCTGTCGCCAACATCGACGAGT
TACGTAACCCGAGCGTGCCCAAGGTGGTGGTTCGCCCGGATGGGCGTCTGCTGTACATGTCGCGCGCGGCGATCCCGGTC
ACCAAGCAAGGCGAGTTCCGGCGTGCCTGGCGGCAGGTGTGTGCGTACGCGTTTCCCAAACAAGCCTTGCAGGCGTTTGC
GTCGGTATCTTGCAAGACCACGTTGGAAGACATTGAGGACATCGAGATCCTGCGTTTTCTGGAACTTGGCTTTGAAGTGC
GTATGGTGCAGATGAGCAACCAATCGATCGCGGTGGATACGCCGGCTGATGTCGTGCGGGTGGAAGCAGCACTACGCATG
ACGCAGCTCGGCGAGCGGAACGCGCCATGA

Upstream 100 bases:

>100_bases
AAGCAGTCAGCCGGCTGGCGCTCAATTCGACCGACTTCTGGCAAGGACGAGCGGGCTGACCGCTCCGAACGGCCAATATA
TCGGTTGCCAGGAGGCTTCC

Downstream 100 bases:

>100_bases
CGCAGGATAAGATGCCCCACACGCCGCCCGGCGTGCATTCGCCCATCTGTGGCACTTCCGATCTCAGAAATGAAGAACAT
GCCCGGGCGTATTCGCCACG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTYAIIIPARRDSSRLPGKPLIELGGVPMIVRTYQQCAKAAPAERILVATDCDVIQRTCEQAGIRTLMTSSDCLTGTDRV
AEVAQQLDVDTYINVQGDDPLFNPQDVRLLIDAAAASPNDVINGYCPVANIDELRNPSVPKVVVRPDGRLLYMSRAAIPV
TKQGEFRRAWRQVCAYAFPKQALQAFASVSCKTTLEDIEDIEILRFLELGFEVRMVQMSNQSIAVDTPADVVRVEAALRM
TQLGERNAP

Sequences:

>Translated_249_residues
MTYAIIIPARRDSSRLPGKPLIELGGVPMIVRTYQQCAKAAPAERILVATDCDVIQRTCEQAGIRTLMTSSDCLTGTDRV
AEVAQQLDVDTYINVQGDDPLFNPQDVRLLIDAAAASPNDVINGYCPVANIDELRNPSVPKVVVRPDGRLLYMSRAAIPV
TKQGEFRRAWRQVCAYAFPKQALQAFASVSCKTTLEDIEDIEILRFLELGFEVRMVQMSNQSIAVDTPADVVRVEAALRM
TQLGERNAP
>Mature_248_residues
TYAIIIPARRDSSRLPGKPLIELGGVPMIVRTYQQCAKAAPAERILVATDCDVIQRTCEQAGIRTLMTSSDCLTGTDRVA
EVAQQLDVDTYINVQGDDPLFNPQDVRLLIDAAAASPNDVINGYCPVANIDELRNPSVPKVVVRPDGRLLYMSRAAIPVT
KQGEFRRAWRQVCAYAFPKQALQAFASVSCKTTLEDIEDIEILRFLELGFEVRMVQMSNQSIAVDTPADVVRVEAALRMT
QLGERNAP

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=251, Percent_Identity=36.2549800796813, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27452; Mature: 27321

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYAIIIPARRDSSRLPGKPLIELGGVPMIVRTYQQCAKAAPAERILVATDCDVIQRTCE
CEEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
QAGIRTLMTSSDCLTGTDRVAEVAQQLDVDTYINVQGDDPLFNPQDVRLLIDAAAASPND
HHCHHEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCC
VINGYCPVANIDELRNPSVPKVVVRPDGRLLYMSRAAIPVTKQGEFRRAWRQVCAYAFPK
CCCCCCCCCCHHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCHH
QALQAFASVSCKTTLEDIEDIEILRFLELGFEVRMVQMSNQSIAVDTPADVVRVEAALRM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCHHHHHHHHHHHH
TQLGERNAP
HHHCCCCCC
>Mature Secondary Structure 
TYAIIIPARRDSSRLPGKPLIELGGVPMIVRTYQQCAKAAPAERILVATDCDVIQRTCE
EEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
QAGIRTLMTSSDCLTGTDRVAEVAQQLDVDTYINVQGDDPLFNPQDVRLLIDAAAASPND
HHCHHEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCC
VINGYCPVANIDELRNPSVPKVVVRPDGRLLYMSRAAIPVTKQGEFRRAWRQVCAYAFPK
CCCCCCCCCCHHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCHH
QALQAFASVSCKTTLEDIEDIEILRFLELGFEVRMVQMSNQSIAVDTPADVVRVEAALRM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCHHHHHHHHHHHH
TQLGERNAP
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA