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The map label for this gene is yhdG [H]

Identifier: 78047443

GI number: 78047443

Start: 2133366

End: 2134796

Strand: Reverse

Name: yhdG [H]

Synonym: XCV1887

Alternate gene names: 78047443

Gene position: 2134796-2133366 (Counterclockwise)

Preceding gene: 78047444

Following gene: 78047442

Centisome position: 41.22

GC content: 65.97

Gene sequence:

>1431_bases
ATGTTCAAACAACTTTGGGCCACCAAACACCCGCACGCCAGCCATGAGGCGGCCGACGGGCTGGGCCTGCAACGCGCGCT
TGGCCCCTGGGGGCTGACCGCCCTGGGAATCGGCGCGGTGATCGGCGGCGGCATCTTCGTCATCACCGGCCAGGCGGCGG
CCGACCATGCCGGCCCGGCGATCATGCTCTCGTTCGTGCTCGCAGCGGTGTGCTGTGCGTTCTGTGCGATGGCCTACGCC
GAATTCGCTGCGATGGTGCCGGTCTCCGGCAGCGCCTACACCTACACCTACGCCACCTTCGGCGAGCTGGCCGCGTGGCT
CATCGGCTGGATGCTGGTGCTGGAATACGGCGTGTCTGCCTCGGCAGTGGCGGTCAGCTGGACCGGCTACTTCTTGAGCC
TGCTCGAGCATTTCGACATCCACCTGCCGGCCGCATTCGTCAGCGCGCCGCTGGACGGCAAATTGCAACCCACCGGGGCG
ATCGCCAACCTGCCGGCGGCCGGGATCGTGCTGCTGCTGACATGGCTGTGCTATGTCGGCATCCGCAAGTCGTCGGCAAT
GAACATGGCCATGGTGATCCTCAAGACGGGCTTGATCCTGCTGGTGATCGCGGTAGGCTGGAAATACGTGGACACCTCCA
ACTGGCACCCGTTCATCCCGGCCAACGAAGGCCCGGGCAAGTACGGCATGGAAGGCGTGCTGCGCGGCGCAGCGATGGTG
TTCTTCGCCTATATCGGCTTCGAAGCGGTGTCGGTGGCGGCGCAGGAATCGCATCGCCCGCAACGCGACCTGCCGATCGG
CATGATCCTGTCGCTGGTGATCTGCACCGTGCTCTACATCGCGATGGCGGCGGTCATGACCGGCTTGGTGCCGTACACCC
TGCTCGGCACCGACGAGCCGGTGGTGACCGCGGTGGCGGCGCATTCGCAGCTGGCCTGGTTGCGCGTGGTCGTGGAAGTG
GGCGCGTTGATCGGGCTGTCGTCGGTGGTGCTGGTGATGATCATCGGGCAGCCGCGCATCTTCATGATCATTGCGCGCGA
TGGCCTGCTGCCCTCGATCTTCACCCGCATCCACCCCAAGTACCGCACCCCGCATGTCAATACCGTCATCACCGGTGTCG
GCATCGCACTGCTGGCAGCGGTGTTCCCGCTGGATGTGCTGGGCGAACTGACGTCGATGGGCACGCTGATCGCCTTCGCG
GCGGTCTGCGCCGGCGTGCTGATCCTGCGTCGCACGCACCCGGAACTGCCGCGTCCGTTCCGCATGCCGGCCGCCTGGCT
GATCTGCAGCGCCGGCGTGTTGAGCTGCCTTGCGCTGCTATCGGCGATGACGCTGCACAACTGGATGCTGATGGGCCTGT
GGACGCTGGTCGGGCTGGTGATCTACTTCGGCTATGGGTATCGCCACAGCCGTCTGCGCGACGGCCGCTGA

Upstream 100 bases:

>100_bases
AGTCGCCTCGCGAAACGGGCCTAAGCTTCTCTCAAGACCGGCGCGCGACGCCGGTCTTCTTGTTCAATGACCGCGCGTAG
CGCCAAGCCGGAACCGCTTC

Downstream 100 bases:

>100_bases
GCCCACGCATGATCGGGCGTCTGGCGCGGCAGGACGATGCCTGCTGCGCTGCACCTGCCCATGCACCGGGGGCGCAGTAG
AATAGGTCCATGAATGCGAC

Product: amino acid-polyamine-organocation superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPAIMLSFVLAAVCCAFCAMAYA
EFAAMVPVSGSAYTYTYATFGELAAWLIGWMLVLEYGVSASAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGA
IANLPAAGIVLLLTWLCYVGIRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEPVVTAVAAHSQLAWLRVVVEV
GALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPKYRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFA
AVCAGVLILRRTHPELPRPFRMPAAWLICSAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR

Sequences:

>Translated_476_residues
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPAIMLSFVLAAVCCAFCAMAYA
EFAAMVPVSGSAYTYTYATFGELAAWLIGWMLVLEYGVSASAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGA
IANLPAAGIVLLLTWLCYVGIRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEPVVTAVAAHSQLAWLRVVVEV
GALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPKYRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFA
AVCAGVLILRRTHPELPRPFRMPAAWLICSAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR
>Mature_476_residues
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPAIMLSFVLAAVCCAFCAMAYA
EFAAMVPVSGSAYTYTYATFGELAAWLIGWMLVLEYGVSASAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGA
IANLPAAGIVLLLTWLCYVGIRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEPVVTAVAAHSQLAWLRVVVEV
GALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPKYRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFA
AVCAGVLILRRTHPELPRPFRMPAAWLICSAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=422, Percent_Identity=34.1232227488152, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI258614003, Length=422, Percent_Identity=34.1232227488152, Blast_Score=215, Evalue=9e-56,
Organism=Homo sapiens, GI114326544, Length=414, Percent_Identity=34.5410628019324, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI114326550, Length=414, Percent_Identity=34.5410628019324, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI258645169, Length=422, Percent_Identity=34.3601895734597, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI4507047, Length=443, Percent_Identity=31.1512415349887, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI110347453, Length=389, Percent_Identity=34.4473007712082, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI181337167, Length=396, Percent_Identity=33.0808080808081, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI71979932, Length=452, Percent_Identity=27.8761061946903, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI33286428, Length=433, Percent_Identity=25.4041570438799, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI115648063, Length=429, Percent_Identity=22.8438228438228, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI115648022, Length=429, Percent_Identity=22.8438228438228, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI186910308, Length=424, Percent_Identity=24.0566037735849, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186910306, Length=424, Percent_Identity=24.0566037735849, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186910304, Length=424, Percent_Identity=24.0566037735849, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI187423910, Length=462, Percent_Identity=20.7792207792208, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7657591, Length=462, Percent_Identity=20.7792207792208, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7657683, Length=368, Percent_Identity=23.6413043478261, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI71999149, Length=426, Percent_Identity=23.0046948356808, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082250, Length=431, Percent_Identity=23.8979118329466, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081869, Length=401, Percent_Identity=22.4438902743142, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788480, Length=387, Percent_Identity=24.2894056847545, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786694, Length=403, Percent_Identity=24.0694789081886, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081915, Length=456, Percent_Identity=23.6842105263158, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=395, Percent_Identity=36.2025316455696, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17531343, Length=422, Percent_Identity=33.6492890995261, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17533459, Length=395, Percent_Identity=34.6835443037975, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17540018, Length=451, Percent_Identity=24.8337028824834, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17568033, Length=427, Percent_Identity=23.8875878220141, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566699, Length=382, Percent_Identity=24.6073298429319, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982612, Length=428, Percent_Identity=22.4299065420561, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982608, Length=428, Percent_Identity=22.4299065420561, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24666159, Length=417, Percent_Identity=34.052757793765, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI221512776, Length=417, Percent_Identity=34.052757793765, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24667468, Length=410, Percent_Identity=35.3658536585366, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24668806, Length=426, Percent_Identity=31.6901408450704, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI21356285, Length=426, Percent_Identity=31.6901408450704, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24668802, Length=426, Percent_Identity=31.6901408450704, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI281366235, Length=415, Percent_Identity=32.289156626506, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI116007820, Length=415, Percent_Identity=32.289156626506, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI116007818, Length=415, Percent_Identity=32.289156626506, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI85725152, Length=415, Percent_Identity=32.289156626506, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI161077963, Length=410, Percent_Identity=32.9268292682927, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI45550968, Length=471, Percent_Identity=22.7176220806794, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921172, Length=471, Percent_Identity=22.7176220806794, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221331183, Length=441, Percent_Identity=24.7165532879819, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17647653, Length=441, Percent_Identity=24.7165532879819, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24664379, Length=441, Percent_Identity=24.7165532879819, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357367, Length=424, Percent_Identity=25.7075471698113, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24651635, Length=408, Percent_Identity=24.5098039215686, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24651633, Length=408, Percent_Identity=24.5098039215686, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641993, Length=409, Percent_Identity=22.9828850855746, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641995, Length=409, Percent_Identity=22.9828850855746, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50809; Mature: 50809

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPA
CCHHHHCCCCCCCCCHHHCCCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHH
IMLSFVLAAVCCAFCAMAYAEFAAMVPVSGSAYTYTYATFGELAAWLIGWMLVLEYGVSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC
SAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGAIANLPAAGIVLLLTWLCYVG
CCEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
IRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
CCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCH
VVTAVAAHSQLAWLRVVVEVGALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCHHHHHHHCCCC
YRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFAAVCAGVLILRRTHPELPRPF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RMPAAWLICSAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPA
CCHHHHCCCCCCCCCHHHCCCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHH
IMLSFVLAAVCCAFCAMAYAEFAAMVPVSGSAYTYTYATFGELAAWLIGWMLVLEYGVSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC
SAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGAIANLPAAGIVLLLTWLCYVG
CCEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
IRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
CCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCH
VVTAVAAHSQLAWLRVVVEVGALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCHHHHHHHCCCC
YRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFAAVCAGVLILRRTHPELPRPF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RMPAAWLICSAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]