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The map label for this gene is yaeL [C]

Identifier: 78047027

GI number: 78047027

Start: 1653567

End: 1654913

Strand: Reverse

Name: yaeL [C]

Synonym: XCV1471

Alternate gene names: 78047027

Gene position: 1654913-1653567 (Counterclockwise)

Preceding gene: 78047028

Following gene: 78047026

Centisome position: 31.96

GC content: 65.7

Gene sequence:

>1347_bases
ATGGGTGATTTCATCGGTTCGGTCTGGTGGATGATCGTCAGCCTGGGCGTGTTGGTGACCTTTCACGAATTCGGGCATTT
CTGGGTGGCGCGGCGCTGCGGCGTCAAGGTGCTGCGCTTTTCGGTGGGCTTCGGCAAACCGCTGTGGATGCGCCGCAACC
GCCACGGCACCGAGTTCGTGGTTGCCGCGATTCCGCTGGGCGGCTACGTCAAAATGCTCGACGAGCGCGAAGGCGACGTG
CATCCGGCCGAGCAGGGCCAAGCCTTCAATCGCAAGACCGTGTGGCAGCGCATCGCGATCGTCGCAGCCGGTCCCATTGC
CAACCTGTTGCTGTGCATGGCGATGCTGTGGGCGATGTTCGTGGTAGGCAAGCAGGATTATTCGGCAACCATTGGTCGGG
CCGATGGCCTGGCCGCCGAGGCCGGGCTGGGCCCGGGCGAGCGCATCGTGCGCATCGACGGTCGCAGCGTGAGCAGCTGG
AGCGATGCCAGCATGCAGCTCACCACTGCGGCAATGGACAGGCGCGATGTCCGCGTCCTGACCGCCTCTGACGCTGCGGG
CAGCAGTGAGCACACCTTGCGCTTGTCGCAGCTGCCGGTCGGTTTCGACGAACGCCGCGTGGCCGCACTGGCCGGCATCG
GCTGGCAGTTCATGCTGAAGCCACCGGTGATTGCCGAAGTGGTGAAGGGCTCGGTGGCCGATGGCCTGCTCAAGCCGGGC
GACCGCATCGTGGCCATCGACGGCCAGCCGATCCGCTCGGCCGAAGACATCATTCCGCAAGTTCAGGCGTTGGGCGCCCA
CGGCGGGCCGGGCATGATCGAGGTGGCGCGCGGCGAAGACCGGCTGGCGCTGGAGATTGCCCCGCGCAAGTCGCCGCAGG
GCCAATGGATGATCGGCGTGCGTCCGGCCGCTGCGCCGGCTCCGGAATACGACAGCCGCCAGCAGTACGGGCTGTTCGCC
GCCGTGCCGGCCGCGATCCGCGAAACCGGCCGGATGACCGCCGACTCGCTGGGCATGATGAAGCGCATGCTGACCGGCCA
GGCCTCGGTCAAGAACATCTCCGGCCCGGTCACCATTGCGCGTGCCGCCAACGCCTCGGCCGAACGCGGGCTCGACTGGT
TCCTGTATTTCCTCGGATTGCTGTCGCTCAGCCTTGCGATCATCAACCTGATGCCCATCCCGATCTTGGACGGTGGGCAT
CTGCTGTATTACCTTATCGAGTTGATCAAGGGCAGCCCGATCAGCGAACGGGCCATGATTGCCGGACAATACGTCGGCCT
GGCGGTCCTGGCCGGGTTGATGGGACTGGCGTTCTACAACGACATCCTCGGCCTGGTTCCACGATGA

Upstream 100 bases:

>100_bases
CCCTGCTTTTTGCCGATGCGCAAGCCCGGCAAATCACTGAACGCGCCCTCGCCCACCACGCCCTTCATGCCTGATCGTTC
CACGCACGCGAGCTGCACAC

Downstream 100 bases:

>100_bases
AGCTGCTCCACTCTTTCCGCCTGTTGTCGTCGTCATACGCCGGCATCCAGCAACACCCGAATACGACTCCAACCGGATGT
GACATGACGCGTCTTCCCAC

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MGDFIGSVWWMIVSLGVLVTFHEFGHFWVARRCGVKVLRFSVGFGKPLWMRRNRHGTEFVVAAIPLGGYVKMLDEREGDV
HPAEQGQAFNRKTVWQRIAIVAAGPIANLLLCMAMLWAMFVVGKQDYSATIGRADGLAAEAGLGPGERIVRIDGRSVSSW
SDASMQLTTAAMDRRDVRVLTASDAAGSSEHTLRLSQLPVGFDERRVAALAGIGWQFMLKPPVIAEVVKGSVADGLLKPG
DRIVAIDGQPIRSAEDIIPQVQALGAHGGPGMIEVARGEDRLALEIAPRKSPQGQWMIGVRPAAAPAPEYDSRQQYGLFA
AVPAAIRETGRMTADSLGMMKRMLTGQASVKNISGPVTIARAANASAERGLDWFLYFLGLLSLSLAIINLMPIPILDGGH
LLYYLIELIKGSPISERAMIAGQYVGLAVLAGLMGLAFYNDILGLVPR

Sequences:

>Translated_448_residues
MGDFIGSVWWMIVSLGVLVTFHEFGHFWVARRCGVKVLRFSVGFGKPLWMRRNRHGTEFVVAAIPLGGYVKMLDEREGDV
HPAEQGQAFNRKTVWQRIAIVAAGPIANLLLCMAMLWAMFVVGKQDYSATIGRADGLAAEAGLGPGERIVRIDGRSVSSW
SDASMQLTTAAMDRRDVRVLTASDAAGSSEHTLRLSQLPVGFDERRVAALAGIGWQFMLKPPVIAEVVKGSVADGLLKPG
DRIVAIDGQPIRSAEDIIPQVQALGAHGGPGMIEVARGEDRLALEIAPRKSPQGQWMIGVRPAAAPAPEYDSRQQYGLFA
AVPAAIRETGRMTADSLGMMKRMLTGQASVKNISGPVTIARAANASAERGLDWFLYFLGLLSLSLAIINLMPIPILDGGH
LLYYLIELIKGSPISERAMIAGQYVGLAVLAGLMGLAFYNDILGLVPR
>Mature_447_residues
GDFIGSVWWMIVSLGVLVTFHEFGHFWVARRCGVKVLRFSVGFGKPLWMRRNRHGTEFVVAAIPLGGYVKMLDEREGDVH
PAEQGQAFNRKTVWQRIAIVAAGPIANLLLCMAMLWAMFVVGKQDYSATIGRADGLAAEAGLGPGERIVRIDGRSVSSWS
DASMQLTTAAMDRRDVRVLTASDAAGSSEHTLRLSQLPVGFDERRVAALAGIGWQFMLKPPVIAEVVKGSVADGLLKPGD
RIVAIDGQPIRSAEDIIPQVQALGAHGGPGMIEVARGEDRLALEIAPRKSPQGQWMIGVRPAAAPAPEYDSRQQYGLFAA
VPAAIRETGRMTADSLGMMKRMLTGQASVKNISGPVTIARAANASAERGLDWFLYFLGLLSLSLAIINLMPIPILDGGHL
LYYLIELIKGSPISERAMIAGQYVGLAVLAGLMGLAFYNDILGLVPR

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=466, Percent_Identity=39.2703862660944, Blast_Score=296, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48295; Mature: 48164

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDFIGSVWWMIVSLGVLVTFHEFGHFWVARRCGVKVLRFSVGFGKPLWMRRNRHGTEFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCEEE
VAAIPLGGYVKMLDEREGDVHPAEQGQAFNRKTVWQRIAIVAAGPIANLLLCMAMLWAMF
EEEECCCHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VVGKQDYSATIGRADGLAAEAGLGPGERIVRIDGRSVSSWSDASMQLTTAAMDRRDVRVL
HHCCCCCHHHCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCCEEEEHHHHCCCCEEEE
TASDAAGSSEHTLRLSQLPVGFDERRVAALAGIGWQFMLKPPVIAEVVKGSVADGLLKPG
EECCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHCHHHHHCCCCC
DRIVAIDGQPIRSAEDIIPQVQALGAHGGPGMIEVARGEDRLALEIAPRKSPQGQWMIGV
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCCEEEEE
RPAAAPAPEYDSRQQYGLFAAVPAAIRETGRMTADSLGMMKRMLTGQASVKNISGPVTIA
ECCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEE
RAANASAERGLDWFLYFLGLLSLSLAIINLMPIPILDGGHLLYYLIELIKGSPISERAMI
ECCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCHHHHH
AGQYVGLAVLAGLMGLAFYNDILGLVPR
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GDFIGSVWWMIVSLGVLVTFHEFGHFWVARRCGVKVLRFSVGFGKPLWMRRNRHGTEFV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCEEE
VAAIPLGGYVKMLDEREGDVHPAEQGQAFNRKTVWQRIAIVAAGPIANLLLCMAMLWAMF
EEEECCCHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VVGKQDYSATIGRADGLAAEAGLGPGERIVRIDGRSVSSWSDASMQLTTAAMDRRDVRVL
HHCCCCCHHHCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCCEEEEHHHHCCCCEEEE
TASDAAGSSEHTLRLSQLPVGFDERRVAALAGIGWQFMLKPPVIAEVVKGSVADGLLKPG
EECCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHCHHHHHCCCCC
DRIVAIDGQPIRSAEDIIPQVQALGAHGGPGMIEVARGEDRLALEIAPRKSPQGQWMIGV
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCCEEEEE
RPAAAPAPEYDSRQQYGLFAAVPAAIRETGRMTADSLGMMKRMLTGQASVKNISGPVTIA
ECCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEE
RAANASAERGLDWFLYFLGLLSLSLAIINLMPIPILDGGHLLYYLIELIKGSPISERAMI
ECCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCHHHHH
AGQYVGLAVLAGLMGLAFYNDILGLVPR
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]