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The map label for this gene is accA [H]

Identifier: 78047018

GI number: 78047018

Start: 1641428

End: 1642387

Strand: Reverse

Name: accA [H]

Synonym: XCV1462

Alternate gene names: 78047018

Gene position: 1642387-1641428 (Counterclockwise)

Preceding gene: 78047019

Following gene: 78047017

Centisome position: 31.72

GC content: 65.73

Gene sequence:

>960_bases
ATGAATCCTAACTACCTCGACTTCGAGCAACCCATCGCCGATCTGGAAGCAAAGATCCAGGAACTGCGCAAGGCCAGTAC
CGGGCCTGCGGTCAACGTGGAGACCGAAGTGCGGGCGCTGCGCGACAAGCTGCGCGTGCGCACCGCGCAGATCTTCCGCG
ATCTGTCGGCCTGGCAGGTCTCGCAGCTGGCGCGTCATCCGCAGCGCCCGTACACGCTGGACTACATCGACACCATCTGC
GACGAATTCCAGGAGTTGGCCGGCGACCGCGCCTATGCCGACGACAAGGCCATCGTCGGTGGCCTGGGCCGCATCGACGG
GCGCCCGGTGGTGATCATCGGCCACCAGAAGGGCCGCGACACCAAGACCAAGGTGGCGCGCAACTTCGGCATGCCGCGCC
CGGAGGGCTACCGCAAGGCCTTGCGCCTGATGAAGCTGGCCGAGCGCTTCCGCCTGCCGCTGCTGACCTTCATCGACACC
CCCGGCGCCTACCCTGGCATCGGCGCCGAAGAGCGCGGCCAGAGCGAGGCGATCGCGCGCAACCTGCTGGAAATGGCCGA
GCTGAAAATACCGGTGATCTGCACCGTCATCGGCGAAGGCGGCTCCGGCGGCGCGCTGGCCATCGGCGTGGGCGACCGCA
CCTTGATGCTGGAATACGGCACCTATTCGGTGATTTCGCCGGAAGGCTGCGCCTCGATCCTGTGGAAGGACGCGGCTAAG
GCCAAGGACGCCGCCGAACAGCTCGGCCTGACCGCCAAGCGCCTGAAGGGTCTGGGCCTGGTCGACAAGGTGATCCGTGA
ACCCACCGGCGGTGCGCATCGCAATCCCGAACAGATGGGCAAGCGCCTGAAAGCGGTGCTGCTCAACGAGCTGGACGCGC
TGGAAAAGATTCCAGTGGATGCGTTGCTGCAGCAGCGCTACGAGCGCCTGCGCAGCTATGGTGCCTACGAAGGGCATTGA

Upstream 100 bases:

>100_bases
TCCCGAATCCCCAATCCCGGCCATGCAACCGCACGGCTGCGTACGGGCCAGCCACACCGCTTCAGCTACACTCCCCGCCT
TACGTTGACGACGCCATTGC

Downstream 100 bases:

>100_bases
TTCGCACGATGGCCGGCCGCGCCCAGTGCGCGGCCATGGAAAGGACGCCACACCCGCATGTCTCCGCTCCTGCTGATCTC
GCTGCTGCTGCAAGCCGCCT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYIDTIC
DEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDT
PGAYPGIGAEERGQSEAIARNLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVDALLQQRYERLRSYGAYEGH

Sequences:

>Translated_319_residues
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYIDTIC
DEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDT
PGAYPGIGAEERGQSEAIARNLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVDALLQQRYERLRSYGAYEGH
>Mature_319_residues
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYIDTIC
DEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDT
PGAYPGIGAEERGQSEAIARNLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVDALLQQRYERLRSYGAYEGH

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=67.5078864353312, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 35233; Mature: 35233

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQV
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLARHPQRPYTLDYIDTICDEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCC
TKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDTPGAYPGIGAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCHHHHHHH
NLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
HHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEEEEECCEEEECCHHHHHHHHHHHHH
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVD
HHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
ALLQQRYERLRSYGAYEGH
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQV
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLARHPQRPYTLDYIDTICDEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCC
TKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDTPGAYPGIGAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCHHHHHHH
NLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
HHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEEEEECCEEEECCHHHHHHHHHHHHH
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVD
HHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
ALLQQRYERLRSYGAYEGH
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]