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The map label for this gene is barA [H]

Identifier: 78046936

GI number: 78046936

Start: 1560181

End: 1560903

Strand: Reverse

Name: barA [H]

Synonym: XCV1380

Alternate gene names: 78046936

Gene position: 1560903-1560181 (Counterclockwise)

Preceding gene: 78046948

Following gene: 78046925

Centisome position: 30.14

GC content: 67.77

Gene sequence:

>723_bases
ATGAACATGGCCACACGCCAGGAACCCCACCCACGCCTACTGCTGGTGGAAGACGACCCGATCAGCCGCGGGTTCTTGCA
GGCTGTGCTTGAAAGTCTTCCGGCCACGGTCGACTGTGCCGATTCCCTTTCTTCCGCACTCGACCGCGCGCGCGAACGTC
GCCACGACCTCTGGCTGATCGACGTCAACCTCCCCGATGGCACCGGTAGCGGGCTACTGCGTGCATTGCGCCTGCTGCAC
CCGGACGTGCCGGCACTGGCGCACACCGCCGACGCGACCATGTCGATGCAGCACAGCCTGCAGTCCGACGGGTTCCTGGA
AATGCTGGTCAAACCAATGACCTCCGAGCGCCTGCTGCAGGCGGTGCGGCGCGGCCTGGCACGCGGTCGCTACAGCGTGG
CCCCGGTGGGCGTGCTGGACATCGCCGCCAGCGACTGGGACGAGACCGCTGCGCTGAGCGCGCTCAACGGCCAGCAGCAT
CATCTCAATGCCCTGCGCGAGCTGTTCCTGGCCGAGCTGCCGGGCACCCGGGATGCGGTGGATTCGGCCTTGCAGATCAG
CGACGAACAGGCACTGCGCAGCCATCTTCATCGGTTGCAGGCCAGCTGTGGCTTCGTCGGCGCGGCGCGGCTTGCCGGCG
CAGTGCGCCTGCTGCGCGGCGACCCGCACTCGCGGACCGCACGCACCCAATTCCACGCGGCGGTGGCTGCATTGCTGCAT
TGA

Upstream 100 bases:

>100_bases
CCGCGCCGGTCAGCGCAACAATTGTCGCGCCCCGCAAACACAGGCAAACTTCCGCTGCGCGCGACAAATCAGGACGCGGC
ATCGCTGACAAGGAGGCAGC

Downstream 100 bases:

>100_bases
GCGAATCGAGCGCAGCACCTCCTTGCCAGAGGAGGTGTGCCAGACGCCGGCGTCGGTGCGCTTCCGGCTCGCCGCCGCGG
TCGATGCATCGTCGTCCTGC

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MNMATRQEPHPRLLLVEDDPISRGFLQAVLESLPATVDCADSLSSALDRARERRHDLWLIDVNLPDGTGSGLLRALRLLH
PDVPALAHTADATMSMQHSLQSDGFLEMLVKPMTSERLLQAVRRGLARGRYSVAPVGVLDIAASDWDETAALSALNGQQH
HLNALRELFLAELPGTRDAVDSALQISDEQALRSHLHRLQASCGFVGAARLAGAVRLLRGDPHSRTARTQFHAAVAALLH

Sequences:

>Translated_240_residues
MNMATRQEPHPRLLLVEDDPISRGFLQAVLESLPATVDCADSLSSALDRARERRHDLWLIDVNLPDGTGSGLLRALRLLH
PDVPALAHTADATMSMQHSLQSDGFLEMLVKPMTSERLLQAVRRGLARGRYSVAPVGVLDIAASDWDETAALSALNGQQH
HLNALRELFLAELPGTRDAVDSALQISDEQALRSHLHRLQASCGFVGAARLAGAVRLLRGDPHSRTARTQFHAAVAALLH
>Mature_240_residues
MNMATRQEPHPRLLLVEDDPISRGFLQAVLESLPATVDCADSLSSALDRARERRHDLWLIDVNLPDGTGSGLLRALRLLH
PDVPALAHTADATMSMQHSLQSDGFLEMLVKPMTSERLLQAVRRGLARGRYSVAPVGVLDIAASDWDETAALSALNGQQH
HLNALRELFLAELPGTRDAVDSALQISDEQALRSHLHRLQASCGFVGAARLAGAVRLLRGDPHSRTARTQFHAAVAALLH

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=28.3185840707965, Blast_Score=77, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 26107; Mature: 26107

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMATRQEPHPRLLLVEDDPISRGFLQAVLESLPATVDCADSLSSALDRARERRHDLWLI
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEE
DVNLPDGTGSGLLRALRLLHPDVPALAHTADATMSMQHSLQSDGFLEMLVKPMTSERLLQ
EEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHH
AVRRGLARGRYSVAPVGVLDIAASDWDETAALSALNGQQHHLNALRELFLAELPGTRDAV
HHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
DSALQISDEQALRSHLHRLQASCGFVGAARLAGAVRLLRGDPHSRTARTQFHAAVAALLH
HHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNMATRQEPHPRLLLVEDDPISRGFLQAVLESLPATVDCADSLSSALDRARERRHDLWLI
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEE
DVNLPDGTGSGLLRALRLLHPDVPALAHTADATMSMQHSLQSDGFLEMLVKPMTSERLLQ
EEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHH
AVRRGLARGRYSVAPVGVLDIAASDWDETAALSALNGQQHHLNALRELFLAELPGTRDAV
HHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
DSALQISDEQALRSHLHRLQASCGFVGAARLAGAVRLLRGDPHSRTARTQFHAAVAALLH
HHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]