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The map label for this gene is yoeA [H]

Identifier: 78046902

GI number: 78046902

Start: 1510606

End: 1512168

Strand: Reverse

Name: yoeA [H]

Synonym: XCV1346

Alternate gene names: 78046902

Gene position: 1512168-1510606 (Counterclockwise)

Preceding gene: 78046906

Following gene: 78046893

Centisome position: 29.2

GC content: 65.13

Gene sequence:

>1563_bases
ATGCCCAAATCCGCTGTCCTGACCGAAGGCCCGATCGGCAAGAACCTGCTGTTGTTCGCGCTGCCGATCATGGCCGGCAA
CATCGCCCAGTCGCTCAACGGCTCGATCAACGCGATCTGGATCGGCCGCTATCTCGGCGAAGAAGCGCTGACCGCGGCGG
CCAATGCCAACAGCATCATGTTCTTCCTGATCGGCTCGGTGTTCGGCATCGGCATGGCTTCGACCATCCTGATCGGCCAG
GCGATGGGCGCACGCGATATCGCCCAGGCGCGCAAGGTGATGGGCACCAGCGCAAGCTTCTTCGGCGGGCTGTCGGCCGT
GATTGCCGTGCTCGGCTGGTACCTGGCGCCGCATCTGCTGACCGCCATGGGCACGCCCGCCGCCTCGCAAACGCTGGCCG
AAGACTATCTGCGGGTGATCTTCCTGGCGATGCCCACGCTGTATCTGTTCGCCTTCCTGTCGGCGGCCTTGCGCGGCACC
GGCGATGCGCGCACGCCGTTCCGTTTCCTGTTGCTGTCGGTGCTGCTGGATATCGTGTTCAACCCGCTGCTGTTGTTCGG
CATCGGCCCGTTTCCGGCATTGGGCATTGCCGGTGCGGCCTGGGCCACATTGATCGCGCAGGTCGTCGCACTGGCCGGGT
TGCTGGTGTATCTGCGCAACAAACGCCATGTCTTGTGGCTGGGCCGGAGCGACTTGCGCCTGTTTCGCATCGACCCAGCC
ATCCTGCGCGCGTTGATCGTCAAAGGCGTGCCGATGGGCCTGCAGATGGTGATGATCTCGCTGTCGATGATCGCCATGTT
GTCGCTGGTCAATGGCTTCGGCACCGAAACCGCTGCGGCATTCGGCGCAGGATTGCAGCTATGGAACTATGTGCAGATGC
CGGCCATGGCGGTGGGCGCCGCTTGTTCGTCGATGGCCGCGCAGAATGTGGGCGCCGGCCTGTGGCCACGCGTGGATGCG
GTCGCACGTACCGGCATCGCTGCCAATTTCCTGATGACGGGCCTGCTGATCGTGCTGCTGATCCTGTTCGATCGCTGGAC
CCTGGCCCTGTTCCTGCCCGAAGGCAGCGCCACGCTGGAGGTTGCGCGGCACCTCAACCACATCGCGATCTGGTCGTTCC
TGCTGTTCGGTGTCAGCTTCGTGGTCTCGGGTGTGGTGCGCGCCACCGGTGCGGTGATTCCGCCGTTGTTGATCCTGGCG
TTTTCGCTGTGGGGCGTGCGCGTGCCGTTGGCCAACGCGCTGCTGCCGCATCTGGGCGCCGATGCGGTGTGGTGGAGCTT
TCCGATCAGTTCGGCCTGTTCGATGCTGCTGTCGCTGGCGTATTACCGTTGGGGCGGCTGGCGCAAGGCGCGCATGCTGA
CCGCACCCACGCATCCGTCGGATGCTTGCGGCTGCAGCGGAAGTACCCGCGCATCCGGCCTCACCGGTCGCCGACCCGGC
CCCGCTCACCGACGCACCAGGCGGGCAGCAAGTATCGCGGACACCGCAGCGTTAGTTACGTTTGCGGCAGCGTACCGCCG
GGTCCGCAGCCATCCCGAGCACACGCGCTTGGAACCGTCATGA

Upstream 100 bases:

>100_bases
CGATCAGCGCGCCCCACGCCGCCTCGCCGCAAGTGCGCTGCATCCGGGCTCACCTGGGCAATGCTAGTGTGCGCACCTTC
TGCGCGACGATACGACTGCG

Downstream 100 bases:

>100_bases
GATCAGGGTAGCCAGCCTCCATATCTCGACCACCCGCGATCGAGAACACGGGGTTGCTGAAGAATTCCCGCAAGGCGCAG
TGTGCATCATGCGTGGATGC

Product: multi anti extrusion family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MPKSAVLTEGPIGKNLLLFALPIMAGNIAQSLNGSINAIWIGRYLGEEALTAAANANSIMFFLIGSVFGIGMASTILIGQ
AMGARDIAQARKVMGTSASFFGGLSAVIAVLGWYLAPHLLTAMGTPAASQTLAEDYLRVIFLAMPTLYLFAFLSAALRGT
GDARTPFRFLLLSVLLDIVFNPLLLFGIGPFPALGIAGAAWATLIAQVVALAGLLVYLRNKRHVLWLGRSDLRLFRIDPA
ILRALIVKGVPMGLQMVMISLSMIAMLSLVNGFGTETAAAFGAGLQLWNYVQMPAMAVGAACSSMAAQNVGAGLWPRVDA
VARTGIAANFLMTGLLIVLLILFDRWTLALFLPEGSATLEVARHLNHIAIWSFLLFGVSFVVSGVVRATGAVIPPLLILA
FSLWGVRVPLANALLPHLGADAVWWSFPISSACSMLLSLAYYRWGGWRKARMLTAPTHPSDACGCSGSTRASGLTGRRPG
PAHRRTRRAASIADTAALVTFAAAYRRVRSHPEHTRLEPS

Sequences:

>Translated_520_residues
MPKSAVLTEGPIGKNLLLFALPIMAGNIAQSLNGSINAIWIGRYLGEEALTAAANANSIMFFLIGSVFGIGMASTILIGQ
AMGARDIAQARKVMGTSASFFGGLSAVIAVLGWYLAPHLLTAMGTPAASQTLAEDYLRVIFLAMPTLYLFAFLSAALRGT
GDARTPFRFLLLSVLLDIVFNPLLLFGIGPFPALGIAGAAWATLIAQVVALAGLLVYLRNKRHVLWLGRSDLRLFRIDPA
ILRALIVKGVPMGLQMVMISLSMIAMLSLVNGFGTETAAAFGAGLQLWNYVQMPAMAVGAACSSMAAQNVGAGLWPRVDA
VARTGIAANFLMTGLLIVLLILFDRWTLALFLPEGSATLEVARHLNHIAIWSFLLFGVSFVVSGVVRATGAVIPPLLILA
FSLWGVRVPLANALLPHLGADAVWWSFPISSACSMLLSLAYYRWGGWRKARMLTAPTHPSDACGCSGSTRASGLTGRRPG
PAHRRTRRAASIADTAALVTFAAAYRRVRSHPEHTRLEPS
>Mature_519_residues
PKSAVLTEGPIGKNLLLFALPIMAGNIAQSLNGSINAIWIGRYLGEEALTAAANANSIMFFLIGSVFGIGMASTILIGQA
MGARDIAQARKVMGTSASFFGGLSAVIAVLGWYLAPHLLTAMGTPAASQTLAEDYLRVIFLAMPTLYLFAFLSAALRGTG
DARTPFRFLLLSVLLDIVFNPLLLFGIGPFPALGIAGAAWATLIAQVVALAGLLVYLRNKRHVLWLGRSDLRLFRIDPAI
LRALIVKGVPMGLQMVMISLSMIAMLSLVNGFGTETAAAFGAGLQLWNYVQMPAMAVGAACSSMAAQNVGAGLWPRVDAV
ARTGIAANFLMTGLLIVLLILFDRWTLALFLPEGSATLEVARHLNHIAIWSFLLFGVSFVVSGVVRATGAVIPPLLILAF
SLWGVRVPLANALLPHLGADAVWWSFPISSACSMLLSLAYYRWGGWRKARMLTAPTHPSDACGCSGSTRASGLTGRRPGP
AHRRTRRAASIADTAALVTFAAAYRRVRSHPEHTRLEPS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=303, Percent_Identity=21.7821782178218, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 55307; Mature: 55176

Theoretical pI: Translated: 11.17; Mature: 11.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKSAVLTEGPIGKNLLLFALPIMAGNIAQSLNGSINAIWIGRYLGEEALTAAANANSIM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCHHHHHHHCCCCHHH
FFLIGSVFGIGMASTILIGQAMGARDIAQARKVMGTSASFFGGLSAVIAVLGWYLAPHLL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TAMGTPAASQTLAEDYLRVIFLAMPTLYLFAFLSAALRGTGDARTPFRFLLLSVLLDIVF
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NPLLLFGIGPFPALGIAGAAWATLIAQVVALAGLLVYLRNKRHVLWLGRSDLRLFRIDPA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECHH
ILRALIVKGVPMGLQMVMISLSMIAMLSLVNGFGTETAAAFGAGLQLWNYVQMPAMAVGA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ACSSMAAQNVGAGLWPRVDAVARTGIAANFLMTGLLIVLLILFDRWTLALFLPEGSATLE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHH
VARHLNHIAIWSFLLFGVSFVVSGVVRATGAVIPPLLILAFSLWGVRVPLANALLPHLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAVWWSFPISSACSMLLSLAYYRWGGWRKARMLTAPTHPSDACGCSGSTRASGLTGRRPG
CHHEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PAHRRTRRAASIADTAALVTFAAAYRRVRSHPEHTRLEPS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PKSAVLTEGPIGKNLLLFALPIMAGNIAQSLNGSINAIWIGRYLGEEALTAAANANSIM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCHHHHHHHCCCCHHH
FFLIGSVFGIGMASTILIGQAMGARDIAQARKVMGTSASFFGGLSAVIAVLGWYLAPHLL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TAMGTPAASQTLAEDYLRVIFLAMPTLYLFAFLSAALRGTGDARTPFRFLLLSVLLDIVF
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NPLLLFGIGPFPALGIAGAAWATLIAQVVALAGLLVYLRNKRHVLWLGRSDLRLFRIDPA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECHH
ILRALIVKGVPMGLQMVMISLSMIAMLSLVNGFGTETAAAFGAGLQLWNYVQMPAMAVGA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ACSSMAAQNVGAGLWPRVDAVARTGIAANFLMTGLLIVLLILFDRWTLALFLPEGSATLE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHH
VARHLNHIAIWSFLLFGVSFVVSGVVRATGAVIPPLLILAFSLWGVRVPLANALLPHLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAVWWSFPISSACSMLLSLAYYRWGGWRKARMLTAPTHPSDACGCSGSTRASGLTGRRPG
CHHEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PAHRRTRRAASIADTAALVTFAAAYRRVRSHPEHTRLEPS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]