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The map label for this gene is echA17 [H]

Identifier: 78046836

GI number: 78046836

Start: 1436265

End: 1437035

Strand: Reverse

Name: echA17 [H]

Synonym: XCV1280

Alternate gene names: 78046836

Gene position: 1437035-1436265 (Counterclockwise)

Preceding gene: 78046838

Following gene: 78046835

Centisome position: 27.75

GC content: 68.74

Gene sequence:

>771_bases
ATGAGCATCCAGATCTTAGACCATGGCCGTCTTCGCGAAATCCGTCTGGCGCGTCCGCCGGTCAATGCGCTGGACAGCGC
GTTGTGCCAGGCGTTGAGCGTCGCGGTCCAGCAGGCGGGCGAGGAAGTCGATGGCATCGTGCTGTCGGGCAGCGAGCGGA
TTTTTTCCGGCGGCATGGATGTGCCGCATCTGCTGGCGCACGGTACCGACCGCGCCGCGCTACTGGCCAGTTGGACCGCG
TTCTTCGATGCGGCGCAGGCGCTGGCCAACAGCCGCGTGCCGGTGGTGGCGGCCATCGGCGGGCATGCGCCGGCCGGCGG
CTGCGTGCTGGCGCTGTGCTGCGACTACCGGGTGATGGCACGCAGTGCCGATACCGCAAGACCCTATACGATCGGCCTCA
ACGAGGTGCAGGTTGGCCTTGCTGCGCCAGAGGGGATCCAACGCCTATTGCGCCGCGTGGTGGGCGCGCACCGCGCCGAA
CGCCTGCTGATCTCCGGGCAACTGCTGCCGGCCGAACAGGCGGTGGCGATCGGGCTGGTGGACGAACTGGTCGATGGCGA
GCTGGTCACCGCGCGTGCGGTGGCGTGGCTCCAGGAGCTGCAGCAGCTCCCCCGCCAACCGATGTTGACCACGCGCGCGA
TTGCGCGTGCCGACCTGCGCGCGGCATTGGCGCCGGAGTTGATCCAGCTGGAGCGTTTCATCGATGGCTGGTACGCGCCG
GATGCGCAGGCCGCGCTGCATGGCCTGGTGGCGCGCCTGCAAAAGGCCTGA

Upstream 100 bases:

>100_bases
GCACTTGCCACCAGCGCCAACGCCGCGAGCACCACGCCGGCACACCTAACCCGCCTGCTTCGACTGCCGTCTATCATGAC
CTGACCTCCAGGAGCCCCGA

Downstream 100 bases:

>100_bases
GCCCTGCCTCGCGGCGCCCATTGGGCGGGCCGGTATACTCGCGTTCCGTCGCATGTCCAGGCCAGCCCCTTGTCCGCCAC
CGCCGAACCCGTCGTCTCCG

Product: putative enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSIQILDHGRLREIRLARPPVNALDSALCQALSVAVQQAGEEVDGIVLSGSERIFSGGMDVPHLLAHGTDRAALLASWTA
FFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMARSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAE
RLLISGQLLPAEQAVAIGLVDELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
DAQAALHGLVARLQKA

Sequences:

>Translated_256_residues
MSIQILDHGRLREIRLARPPVNALDSALCQALSVAVQQAGEEVDGIVLSGSERIFSGGMDVPHLLAHGTDRAALLASWTA
FFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMARSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAE
RLLISGQLLPAEQAVAIGLVDELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
DAQAALHGLVARLQKA
>Mature_255_residues
SIQILDHGRLREIRLARPPVNALDSALCQALSVAVQQAGEEVDGIVLSGSERIFSGGMDVPHLLAHGTDRAALLASWTAF
FDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMARSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAER
LLISGQLLPAEQAVAIGLVDELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAPD
AQAALHGLVARLQKA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI62530384, Length=251, Percent_Identity=30.6772908366534, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI295842266, Length=251, Percent_Identity=26.6932270916335, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI68989263, Length=199, Percent_Identity=32.1608040201005, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI194097323, Length=250, Percent_Identity=26, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790281, Length=185, Percent_Identity=31.8918918918919, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787659, Length=186, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583165, Length=258, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19921018, Length=189, Percent_Identity=33.8624338624339, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45550169, Length=257, Percent_Identity=29.1828793774319, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129971, Length=187, Percent_Identity=30.4812834224599, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24653477, Length=187, Percent_Identity=30.4812834224599, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27257; Mature: 27126

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQILDHGRLREIRLARPPVNALDSALCQALSVAVQQAGEEVDGIVLSGSERIFSGGMD
CEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCEEEECCCHHHCCCCC
VPHLLAHGTDRAALLASWTAFFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAERLLISGQLLPAEQAVAIGLV
CCCCCCCCEEECHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
DELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAQAALHGLVARLQKA
CHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIQILDHGRLREIRLARPPVNALDSALCQALSVAVQQAGEEVDGIVLSGSERIFSGGMD
EEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCEEEECCCHHHCCCCC
VPHLLAHGTDRAALLASWTAFFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAERLLISGQLLPAEQAVAIGLV
CCCCCCCCEEECHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
DELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAQAALHGLVARLQKA
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA