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The map label for this gene is yeaE [H]

Identifier: 78046797

GI number: 78046797

Start: 1393677

End: 1394531

Strand: Reverse

Name: yeaE [H]

Synonym: XCV1241

Alternate gene names: 78046797

Gene position: 1394531-1393677 (Counterclockwise)

Preceding gene: 78046798

Following gene: 78046796

Centisome position: 26.93

GC content: 65.15

Gene sequence:

>855_bases
ATGTCCGAATCGTCTTCCCCTTCCTGCGCACAGGTGCGCCTGCGCAACGGGCGTCGCGTGCCCGCATTAGGTCTGGGCTC
CTGGAACCTGGGCCAGGGCCGGCATGCGCCCGAGCAGGAAATTCAGGCGCTGCAACTCGGTCAGCAATTGGGGATGCAGC
TGATCGACACCGCCGAGATGTACGGCAATGGCCGCTCTGAGCAACTGATCAGCCAGGCCATCGGCCGTGCGCAGCCGCCC
TACGTGGTGTCCAAGGTGTTGCCCGGCAATGCCAGCGCCCGCGGAATCGCACGCGCCTGCGAAGCCAGCCTGCAACGGCT
GGGGGTGCGCACCTTGGATCTGTATTTGCTGCACTGGCGTGGCGGCAGCGATCTGGCCGAAGTGGTGGATGCATTCGAAG
CACTACGCGATGCCGGCAAGATCCGCGATTGGGGCGTGTCCAACTTCGATGTCGATGACATGGAGGAGCTCTGGGCAATC
GATGGCGGCTCGCGTTGCCTGGTCAACCAGGTGCTGTACCACGCTGGCAGCCGCGGTATCGAATTCGACCTGTTGCCGTG
GTGCGCCGCGCACGAGGTGGCCGTGATGGCCTATTCGCCGCTTGGCAGCCGCGCGTTGCTGGATCATCCGGTCTTGCACG
CCATCGGCGAGCGTCGTGGCGTTGCAGCCACCGCGGTGGCGCTTGCGTGGGCGATCCGCAGCGGCAATGTCATCGCCATT
CCCGAATCCGGAACGCCGGCGCATGTGCGTGCCAATGCCGCGGCCTGCACGCTGCAATTGCACGCAGACGATCTTGCCGA
GATCGATCGCGCCTTCGCGCCGCCTACCCGCAAACAGCCGCTGGATCTGCTGTAA

Upstream 100 bases:

>100_bases
TGCAGACACTGCGACAACATCGGTGCAGCCATCGTCGCCGTGACAGGGCGATCGGTGTGATGCGACCGCCACCCTCATTC
CAACGCGACAGGAACCCATC

Downstream 100 bases:

>100_bases
AACATGGATAGTCGCGCCCGCTTGTCTGCGCATCTGCACGGCTGCGCGTGTGCGTGCTCGTGATCGCTGCAACATGCAAC
TGCGACGTCGCGCAATGTTT

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSESSSPSCAQVRLRNGRRVPALGLGSWNLGQGRHAPEQEIQALQLGQQLGMQLIDTAEMYGNGRSEQLISQAIGRAQPP
YVVSKVLPGNASARGIARACEASLQRLGVRTLDLYLLHWRGGSDLAEVVDAFEALRDAGKIRDWGVSNFDVDDMEELWAI
DGGSRCLVNQVLYHAGSRGIEFDLLPWCAAHEVAVMAYSPLGSRALLDHPVLHAIGERRGVAATAVALAWAIRSGNVIAI
PESGTPAHVRANAAACTLQLHADDLAEIDRAFAPPTRKQPLDLL

Sequences:

>Translated_284_residues
MSESSSPSCAQVRLRNGRRVPALGLGSWNLGQGRHAPEQEIQALQLGQQLGMQLIDTAEMYGNGRSEQLISQAIGRAQPP
YVVSKVLPGNASARGIARACEASLQRLGVRTLDLYLLHWRGGSDLAEVVDAFEALRDAGKIRDWGVSNFDVDDMEELWAI
DGGSRCLVNQVLYHAGSRGIEFDLLPWCAAHEVAVMAYSPLGSRALLDHPVLHAIGERRGVAATAVALAWAIRSGNVIAI
PESGTPAHVRANAAACTLQLHADDLAEIDRAFAPPTRKQPLDLL
>Mature_283_residues
SESSSPSCAQVRLRNGRRVPALGLGSWNLGQGRHAPEQEIQALQLGQQLGMQLIDTAEMYGNGRSEQLISQAIGRAQPPY
VVSKVLPGNASARGIARACEASLQRLGVRTLDLYLLHWRGGSDLAEVVDAFEALRDAGKIRDWGVSNFDVDDMEELWAID
GGSRCLVNQVLYHAGSRGIEFDLLPWCAAHEVAVMAYSPLGSRALLDHPVLHAIGERRGVAATAVALAWAIRSGNVIAIP
ESGTPAHVRANAAACTLQLHADDLAEIDRAFAPPTRKQPLDLL

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=294, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI93277124, Length=298, Percent_Identity=26.1744966442953, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI24497577, Length=301, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI5174391, Length=301, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI310109922, Length=275, Percent_Identity=26.1818181818182, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5453543, Length=295, Percent_Identity=25.4237288135593, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI45446745, Length=295, Percent_Identity=25.4237288135593, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4503285, Length=295, Percent_Identity=25.4237288135593, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI310109920, Length=295, Percent_Identity=25.4237288135593, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI291291012, Length=251, Percent_Identity=28.6852589641434, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI24497585, Length=304, Percent_Identity=24.3421052631579, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI24497583, Length=295, Percent_Identity=25.7627118644068, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4502049, Length=296, Percent_Identity=26.0135135135135, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI5174695, Length=302, Percent_Identity=23.5099337748344, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI300116273, Length=280, Percent_Identity=24.2857142857143, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1788081, Length=271, Percent_Identity=46.4944649446494, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082198, Length=265, Percent_Identity=28.3018867924528, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786400, Length=270, Percent_Identity=28.8888888888889, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788070, Length=301, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081735, Length=308, Percent_Identity=26.9480519480519, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787674, Length=281, Percent_Identity=27.4021352313167, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552492, Length=275, Percent_Identity=30.1818181818182, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17561298, Length=283, Percent_Identity=27.5618374558304, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17538386, Length=279, Percent_Identity=27.9569892473118, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17537077, Length=295, Percent_Identity=26.4406779661017, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17561300, Length=266, Percent_Identity=25.9398496240602, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537075, Length=295, Percent_Identity=26.1016949152542, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17550248, Length=301, Percent_Identity=23.9202657807309, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=24.5487364620939, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324694, Length=286, Percent_Identity=27.6223776223776, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320079, Length=285, Percent_Identity=24.9122807017544, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24662789, Length=302, Percent_Identity=29.8013245033113, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24644950, Length=306, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45553081, Length=292, Percent_Identity=26.027397260274, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356425, Length=299, Percent_Identity=24.7491638795987, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24657054, Length=292, Percent_Identity=25, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129731, Length=288, Percent_Identity=26.3888888888889, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24663317, Length=309, Percent_Identity=23.9482200647249, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30548; Mature: 30417

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESSSPSCAQVRLRNGRRVPALGLGSWNLGQGRHAPEQEIQALQLGQQLGMQLIDTAEM
CCCCCCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YGNGRSEQLISQAIGRAQPPYVVSKVLPGNASARGIARACEASLQRLGVRTLDLYLLHWR
HCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEC
GGSDLAEVVDAFEALRDAGKIRDWGVSNFDVDDMEELWAIDGGSRCLVNQVLYHAGSRGI
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
EFDLLPWCAAHEVAVMAYSPLGSRALLDHPVLHAIGERRGVAATAVALAWAIRSGNVIAI
EEECCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
PESGTPAHVRANAAACTLQLHADDLAEIDRAFAPPTRKQPLDLL
CCCCCCCEEECCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SESSSPSCAQVRLRNGRRVPALGLGSWNLGQGRHAPEQEIQALQLGQQLGMQLIDTAEM
CCCCCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YGNGRSEQLISQAIGRAQPPYVVSKVLPGNASARGIARACEASLQRLGVRTLDLYLLHWR
HCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEC
GGSDLAEVVDAFEALRDAGKIRDWGVSNFDVDDMEELWAIDGGSRCLVNQVLYHAGSRGI
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
EFDLLPWCAAHEVAVMAYSPLGSRALLDHPVLHAIGERRGVAATAVALAWAIRSGNVIAI
EEECCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
PESGTPAHVRANAAACTLQLHADDLAEIDRAFAPPTRKQPLDLL
CCCCCCCEEECCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]