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The map label for this gene is yagR [H]

Identifier: 78046770

GI number: 78046770

Start: 1360274

End: 1362571

Strand: Reverse

Name: yagR [H]

Synonym: XCV1214

Alternate gene names: 78046770

Gene position: 1362571-1360274 (Counterclockwise)

Preceding gene: 78046771

Following gene: 78046766

Centisome position: 26.31

GC content: 65.32

Gene sequence:

>2298_bases
ATGAACGCACGCATCCCCGACCTGTCCGACAGCGCGCTGACCCCGCCGGTTGCCGACAGCGGCACCGGCTATCGCCCCAC
CGGCACCGGCGTCACGCGCATCGACGGACGCGCAAAAGTCACCGGCCAGGCGCGTTATGCCGCCGAATGGCCGGTGCCGG
ACTTGGCCTATGGCGTGGTGGTCAACAGCAGCATTGCCAAGGGTGAGATCGTTGCCTTCCATCTGGATGCAGCACGCGCA
GTCCCCGGCGTGCTGGAGATCGTCACCCATGAAAACCGCCCGCACATGCGCGGCATGGACCTGTTCTACAAGGACATGAC
GGCGCCGGCCGGCTCGCCGTTCCGTCCGTTGTACGACAACAAGATCTTGTACAGCGGCCAGCCCATCGCGCTGGTGGTTG
CCGAGACCTTTGAAGCGGCGCGCCATGCCGCGCATCTGGTGGAAGTGGAGCTGTTGCAGGACCCGCACGACACCAACCTG
ATGACCAACCTGGACCGTGCACACGCGCCCAAGCCGCTGAAGGCCGGATTTTCGCCGCCGCCCAAGGACAAGGGCGATCC
GCAGAGCGCATTCGACAATGCCGCGTGCCAGGTACAGGCCGACTACTACAGCGGCGTCGAGCACCACAACCCGATGGAAT
TGTTCGCTTCCACCGTCATCCGCGACGCCGACGGCCATTTCACCATTTACGACAAAACCCAGGGTTCGCAGAACAGCCGC
TGGTACGTGTCGCACGTGTTCGGGCTGAGCAAGCGCAAGGTGACCGTGCGCAACCCGTACGTGGGAGGCGCGTTCGGCTC
CGGGCTGCGCCCGCAGTATCAGTTGCCGCTGGCGGTGATGGCGTCGATCCTGCTGGATCGCTCGATGCGCGTGGTGCTGA
CGCGACAACAGATGTTCACCTTCGGCCACCGCCCGGAAACGCTGCAGCGGCTCAAGCTCGGCGCAGACCGCGACGGCACC
TTGCGCTCGGTCTGGCATGAAGCCATCGCCGAAACCTCGCGCATCGAAGACTACGTGGAGGTAGTGGTCAACTGGAGCGG
TCAGTTGTACGCCTGCGACAACGTGCACCTGGGCTACAAGCTGGTGAGTCTGGACCAATACAGCCCCATCGACATGCGTG
CGCCCGGCGCCGCGCATGGTGTGCATGCGCTGGAAGTGGCGATGGACGAGTTGGCCTATGAGGTCGGCATCGATCCGTTG
GCACTGCGCCTGAAGAACTACGCCGAGGTCAATCCGGCCGACGACAAGCCCTACTCTACCAAGGCGCTGCGCCAGTGTTA
CGAGCAAGGGGCAGAGCGCTTCGGTTGGGCGCAACGCCCCCTGCAACCGCGCGCGCGCAAGGAAGGCAGCGAGTGGGTGG
GCTGGGGCATGGCCACCGGGCAGTGGGATGCGATGCAGATGTTCGCGCGCGCACATGCGGCGCTGCATGCCGACGGCCGT
TTGGTGGTCAGCAGCGCAGCCAGCGATATCGGCACCGGCACCTACACGGTGATGGCGATGATCGCTGCCGAAGCGCTGGG
CCTGCCCTTGGAGCAGGTGACGTTTCAACTTGGCGACTCCACCTTGCCCGTTGCGCCGATCGAAGGTGGCTCCTCGCACG
TCACCACGGTGGGCTCGGCAGTGGATGGCGTGTGCGCAAAGCTGCGCGGGCGTCTATTGCGTCTGGCCCAGGCCCTGCCC
GACTCGCGCTTTGCCAAGGCCAAACCTGACGATGTGGTCTTTGCCGACGGCACGCTGGCATTGCGGGCCGATGCCGGCAG
CGCCATCGCCCTGACCGACCTGCTGCGCACTGCAGGGCTGGAGCAGATCGAAGATAAGTTCCTCCTGCTGCCGAACGTGC
TCAAGCAACGCAAATACACCCGTGCCACGCACGGCGCGGTGTTTGTGGAGGTCCGGGTGGACGAAGAACTGGGCACGGTG
CGGGTCACCCGCGTGGTCAGCGCCGTTGCCGCCGGGCGCATCCTCAATCCGATCACCGCACGCAGCCAGATTGTGGGGGG
CGTGGTCTGGGGCATCGGCCAGGCGCTGCACGAGCACACCCAATCGGACCATCGCTTCGGCCGCTTCATGAATCACGACC
TGGCGCTGTATCACGTCTCCGCCAACGCCGACATTCACGACATCGACGTGATCTTCGCCGACGAAGACGACCGCGTCGTC
AGCAGCCTGGGTGCGAAGGGCGTGGGCGAGATCGGCCTGGTCGGCGTGTCTGCGGCGATCTGCAACGCCATCTTCCACGC
CACCGGCAAGCGCATCCGCAGCACGCCGATGACGCCGGACAAGGTGATGGCGGACTGA

Upstream 100 bases:

>100_bases
AGCTGCCGCTGGCACGCCGCGCCATCGTGCGCGCATTGAGCGTTGCGCGCGAGGGCACCATCGACAACCGCGGGCGCACC
AGTGCGCTGGAGGAATCGCC

Downstream 100 bases:

>100_bases
CCTGCAGCGTACGTTGCGCTTGCAGGCAATGCTTGGCGCCTTGGGTAGTGAAGTGAAGTGATCCCAACAGTCGGGCCCAA
TGCAGCGATGCATTGGGCCC

Product: xanthine dehydrogenase, molybdenum-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MNARIPDLSDSALTPPVADSGTGYRPTGTGVTRIDGRAKVTGQARYAAEWPVPDLAYGVVVNSSIAKGEIVAFHLDAARA
VPGVLEIVTHENRPHMRGMDLFYKDMTAPAGSPFRPLYDNKILYSGQPIALVVAETFEAARHAAHLVEVELLQDPHDTNL
MTNLDRAHAPKPLKAGFSPPPKDKGDPQSAFDNAACQVQADYYSGVEHHNPMELFASTVIRDADGHFTIYDKTQGSQNSR
WYVSHVFGLSKRKVTVRNPYVGGAFGSGLRPQYQLPLAVMASILLDRSMRVVLTRQQMFTFGHRPETLQRLKLGADRDGT
LRSVWHEAIAETSRIEDYVEVVVNWSGQLYACDNVHLGYKLVSLDQYSPIDMRAPGAAHGVHALEVAMDELAYEVGIDPL
ALRLKNYAEVNPADDKPYSTKALRQCYEQGAERFGWAQRPLQPRARKEGSEWVGWGMATGQWDAMQMFARAHAALHADGR
LVVSSAASDIGTGTYTVMAMIAAEALGLPLEQVTFQLGDSTLPVAPIEGGSSHVTTVGSAVDGVCAKLRGRLLRLAQALP
DSRFAKAKPDDVVFADGTLALRADAGSAIALTDLLRTAGLEQIEDKFLLLPNVLKQRKYTRATHGAVFVEVRVDEELGTV
RVTRVVSAVAAGRILNPITARSQIVGGVVWGIGQALHEHTQSDHRFGRFMNHDLALYHVSANADIHDIDVIFADEDDRVV
SSLGAKGVGEIGLVGVSAAICNAIFHATGKRIRSTPMTPDKVMAD

Sequences:

>Translated_765_residues
MNARIPDLSDSALTPPVADSGTGYRPTGTGVTRIDGRAKVTGQARYAAEWPVPDLAYGVVVNSSIAKGEIVAFHLDAARA
VPGVLEIVTHENRPHMRGMDLFYKDMTAPAGSPFRPLYDNKILYSGQPIALVVAETFEAARHAAHLVEVELLQDPHDTNL
MTNLDRAHAPKPLKAGFSPPPKDKGDPQSAFDNAACQVQADYYSGVEHHNPMELFASTVIRDADGHFTIYDKTQGSQNSR
WYVSHVFGLSKRKVTVRNPYVGGAFGSGLRPQYQLPLAVMASILLDRSMRVVLTRQQMFTFGHRPETLQRLKLGADRDGT
LRSVWHEAIAETSRIEDYVEVVVNWSGQLYACDNVHLGYKLVSLDQYSPIDMRAPGAAHGVHALEVAMDELAYEVGIDPL
ALRLKNYAEVNPADDKPYSTKALRQCYEQGAERFGWAQRPLQPRARKEGSEWVGWGMATGQWDAMQMFARAHAALHADGR
LVVSSAASDIGTGTYTVMAMIAAEALGLPLEQVTFQLGDSTLPVAPIEGGSSHVTTVGSAVDGVCAKLRGRLLRLAQALP
DSRFAKAKPDDVVFADGTLALRADAGSAIALTDLLRTAGLEQIEDKFLLLPNVLKQRKYTRATHGAVFVEVRVDEELGTV
RVTRVVSAVAAGRILNPITARSQIVGGVVWGIGQALHEHTQSDHRFGRFMNHDLALYHVSANADIHDIDVIFADEDDRVV
SSLGAKGVGEIGLVGVSAAICNAIFHATGKRIRSTPMTPDKVMAD
>Mature_765_residues
MNARIPDLSDSALTPPVADSGTGYRPTGTGVTRIDGRAKVTGQARYAAEWPVPDLAYGVVVNSSIAKGEIVAFHLDAARA
VPGVLEIVTHENRPHMRGMDLFYKDMTAPAGSPFRPLYDNKILYSGQPIALVVAETFEAARHAAHLVEVELLQDPHDTNL
MTNLDRAHAPKPLKAGFSPPPKDKGDPQSAFDNAACQVQADYYSGVEHHNPMELFASTVIRDADGHFTIYDKTQGSQNSR
WYVSHVFGLSKRKVTVRNPYVGGAFGSGLRPQYQLPLAVMASILLDRSMRVVLTRQQMFTFGHRPETLQRLKLGADRDGT
LRSVWHEAIAETSRIEDYVEVVVNWSGQLYACDNVHLGYKLVSLDQYSPIDMRAPGAAHGVHALEVAMDELAYEVGIDPL
ALRLKNYAEVNPADDKPYSTKALRQCYEQGAERFGWAQRPLQPRARKEGSEWVGWGMATGQWDAMQMFARAHAALHADGR
LVVSSAASDIGTGTYTVMAMIAAEALGLPLEQVTFQLGDSTLPVAPIEGGSSHVTTVGSAVDGVCAKLRGRLLRLAQALP
DSRFAKAKPDDVVFADGTLALRADAGSAIALTDLLRTAGLEQIEDKFLLLPNVLKQRKYTRATHGAVFVEVRVDEELGTV
RVTRVVSAVAAGRILNPITARSQIVGGVVWGIGQALHEHTQSDHRFGRFMNHDLALYHVSANADIHDIDVIFADEDDRVV
SSLGAKGVGEIGLVGVSAAICNAIFHATGKRIRSTPMTPDKVMAD

Specific function: Unknown

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=779, Percent_Identity=23.7483953786906, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI91823271, Length=773, Percent_Identity=21.9922380336352, Blast_Score=100, Evalue=7e-21,
Organism=Escherichia coli, GI1786478, Length=735, Percent_Identity=38.2312925170068, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1789230, Length=758, Percent_Identity=27.9683377308707, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1789246, Length=772, Percent_Identity=26.4248704663212, Blast_Score=152, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24647199, Length=697, Percent_Identity=21.9512195121951, Blast_Score=113, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24647193, Length=743, Percent_Identity=22.207267833109, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647201, Length=696, Percent_Identity=21.8390804597701, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17737937, Length=739, Percent_Identity=23.9512855209743, Blast_Score=91, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 83094; Mature: 83094

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARIPDLSDSALTPPVADSGTGYRPTGTGVTRIDGRAKVTGQARYAAEWPVPDLAYGVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCEEEEECCCCCCCEEHEE
VNSSIAKGEIVAFHLDAARAVPGVLEIVTHENRPHMRGMDLFYKDMTAPAGSPFRPLYDN
EECCCCCCCEEEEEECHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
KILYSGQPIALVVAETFEAARHAAHLVEVELLQDPHDTNLMTNLDRAHAPKPLKAGFSPP
EEEECCCCEEEEEHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCC
PKDKGDPQSAFDNAACQVQADYYSGVEHHNPMELFASTVIRDADGHFTIYDKTQGSQNSR
CCCCCCCHHHHCCCEEEEEEHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
WYVSHVFGLSKRKVTVRNPYVGGAFGSGLRPQYQLPLAVMASILLDRSMRVVLTRQQMFT
EEEEEHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHEEEEHHHHHH
FGHRPETLQRLKLGADRDGTLRSVWHEAIAETSRIEDYVEVVVNWSGQLYACDNVHLGYK
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEECEE
LVSLDQYSPIDMRAPGAAHGVHALEVAMDELAYEVGIDPLALRLKNYAEVNPADDKPYST
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCH
KALRQCYEQGAERFGWAQRPLQPRARKEGSEWVGWGMATGQWDAMQMFARAHAALHADGR
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCE
LVVSSAASDIGTGTYTVMAMIAAEALGLPLEQVTFQLGDSTLPVAPIEGGSSHVTTVGSA
EEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCCEEEHHHH
VDGVCAKLRGRLLRLAQALPDSRFAKAKPDDVVFADGTLALRADAGSAIALTDLLRTAGL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHCCH
EQIEDKFLLLPNVLKQRKYTRATHGAVFVEVRVDEELGTVRVTRVVSAVAAGRILNPITA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHH
RSQIVGGVVWGIGQALHEHTQSDHRFGRFMNHDLALYHVSANADIHDIDVIFADEDDRVV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCEEEEEEEEECCCHHHH
SSLGAKGVGEIGLVGVSAAICNAIFHATGKRIRSTPMTPDKVMAD
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHCCC
>Mature Secondary Structure
MNARIPDLSDSALTPPVADSGTGYRPTGTGVTRIDGRAKVTGQARYAAEWPVPDLAYGVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCEEEEECCCCCCCEEHEE
VNSSIAKGEIVAFHLDAARAVPGVLEIVTHENRPHMRGMDLFYKDMTAPAGSPFRPLYDN
EECCCCCCCEEEEEECHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
KILYSGQPIALVVAETFEAARHAAHLVEVELLQDPHDTNLMTNLDRAHAPKPLKAGFSPP
EEEECCCCEEEEEHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCC
PKDKGDPQSAFDNAACQVQADYYSGVEHHNPMELFASTVIRDADGHFTIYDKTQGSQNSR
CCCCCCCHHHHCCCEEEEEEHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
WYVSHVFGLSKRKVTVRNPYVGGAFGSGLRPQYQLPLAVMASILLDRSMRVVLTRQQMFT
EEEEEHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHEEEEHHHHHH
FGHRPETLQRLKLGADRDGTLRSVWHEAIAETSRIEDYVEVVVNWSGQLYACDNVHLGYK
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEECEE
LVSLDQYSPIDMRAPGAAHGVHALEVAMDELAYEVGIDPLALRLKNYAEVNPADDKPYST
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCH
KALRQCYEQGAERFGWAQRPLQPRARKEGSEWVGWGMATGQWDAMQMFARAHAALHADGR
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCE
LVVSSAASDIGTGTYTVMAMIAAEALGLPLEQVTFQLGDSTLPVAPIEGGSSHVTTVGSA
EEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCCEEEHHHH
VDGVCAKLRGRLLRLAQALPDSRFAKAKPDDVVFADGTLALRADAGSAIALTDLLRTAGL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHCCH
EQIEDKFLLLPNVLKQRKYTRATHGAVFVEVRVDEELGTVRVTRVVSAVAAGRILNPITA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHH
RSQIVGGVVWGIGQALHEHTQSDHRFGRFMNHDLALYHVSANADIHDIDVIFADEDDRVV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCEEEEEEEEECCCHHHH
SSLGAKGVGEIGLVGVSAAICNAIFHATGKRIRSTPMTPDKVMAD
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]